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GcL

@grosscol.bsky.social

Programming and human genetics. Working with TOPMED data and providing a view into human variation via BRAVO (bravo.sph.umich.edu)

143 Followers  |  93 Following  |  69 Posts  |  Joined: 29.10.2024  |  2.3804

Latest posts by grosscol.bsky.social on Bluesky

For the first time, I'm glad I don't work with the Ruby ecosystem anymore.

30.10.2025 20:48 โ€” ๐Ÿ‘ 1    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

Still less frustration than dealing with pulse audio.

30.10.2025 17:59 โ€” ๐Ÿ‘ 0    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

There isn't a good way of conveying the depth of groan emitted when reading this in a way that would match the satisfaction you likely derive from knowing it happened.

30.10.2025 16:38 โ€” ๐Ÿ‘ 1    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

Physical terminal is rad.

28.10.2025 18:53 โ€” ๐Ÿ‘ 1    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

/s has been around at least since the 90s which was only like ten years.... Oh no.

25.10.2025 15:22 โ€” ๐Ÿ‘ 1    ๐Ÿ” 0    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 0

This was a useful list. Nice that this platform facilitates blocking lists of bad actors.

20.10.2025 15:03 โ€” ๐Ÿ‘ 0    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

You're the Pratchett quoting guy that rattles on about politics.

19.10.2025 15:30 โ€” ๐Ÿ‘ 0    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

If you rip off my post without liking it, you owe me two dollars.

16.10.2025 20:44 โ€” ๐Ÿ‘ 1    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

As always, your taste in eyewear is excellent.

13.10.2025 01:42 โ€” ๐Ÿ‘ 0    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

That's a heck of a Lego endeavor! Impressive is an understatement.

08.10.2025 22:45 โ€” ๐Ÿ‘ 0    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

Reminds me of a project that had to satisfy a requirement of a contact specifying the solution needed to use machine learning.

We found a linear regression model that worked well enough, and made sure we never clarified beyond "supervised machine learning implementation" in the docs.

07.10.2025 15:54 โ€” ๐Ÿ‘ 0    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

@katmabu.bsky.social keep it up. Good luck!

04.10.2025 16:49 โ€” ๐Ÿ‘ 1    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

@bcdreyer.social how do you edit copy? I thought paste took care of that?! /S

04.10.2025 01:18 โ€” ๐Ÿ‘ 1    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

Excellent. More great work of yours that I will unabashedly yoink for my own collaborative story telling with friends. Thank you.

04.10.2025 00:39 โ€” ๐Ÿ‘ 1    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

@@cherylrofer.bsky.social I came across a post of yours, checked your profile, and found that I liked both.

I have heard a lot about thorium reactors in recent years. What are your thoughts on thorium and thorium reactors?

03.10.2025 17:05 โ€” ๐Ÿ‘ 1    ๐Ÿ” 0    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 0

Watched this yesterday in the background. While nodding along, the offhand comment that you've written a compiler in assembly got my full attention. That's one of the projects where curiosity and masochism share a border.

02.10.2025 16:48 โ€” ๐Ÿ‘ 1    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
Preview
How Fascism Works - Wikipedia

Most people don't have the ability to point out the hallmarks of fascism. My go-to recommendation is en.m.wikipedia.org/wiki/How_Fas...

30.09.2025 22:28 โ€” ๐Ÿ‘ 0    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
Preview
How Fascism Works - Wikipedia

Most people don't have the ability to point out the hallmarks of fascism. My go-to recommendation is en.m.wikipedia.org/wiki/How_Fas...

30.09.2025 21:55 โ€” ๐Ÿ‘ 0    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

Trimming the hedges around the base of the tent helps as well.

30.09.2025 15:35 โ€” ๐Ÿ‘ 1    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

Unfortunately for us on this side of the border, that is a safer and saner stance for you.

28.09.2025 19:37 โ€” ๐Ÿ‘ 0    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

Tipsy women lazing about in pubs handing out cubes is no basis for a system of government!

28.09.2025 13:12 โ€” ๐Ÿ‘ 0    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

*it was originally written in the 1970s
*It has a learning curve
*It is a command line interface

It's blazingly fast to execute and works even when the input has millions of lines.

27.09.2025 13:09 โ€” ๐Ÿ‘ 2    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

Had no clue who you or Heather were, but "commie podcast hags" sold me on following both of you immediately.

25.09.2025 21:14 โ€” ๐Ÿ‘ 0    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

Using an ai generated image for the design feels bad.

25.09.2025 21:12 โ€” ๐Ÿ‘ 0    ๐Ÿ” 0    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 0

This post reads like it was written by an LLM

25.09.2025 14:36 โ€” ๐Ÿ‘ 1    ๐Ÿ” 0    ๐Ÿ’ฌ 2    ๐Ÿ“Œ 0

Those that know history are done to watch everyone else repeat it.

20.09.2025 03:56 โ€” ๐Ÿ‘ 2    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

Being able to hear the disk drive grinding and grumbling away as it reads the floppy disk is an important part of the authentic Oregon Trail experience. Also, where in the world is Carmen Sandeigo?

20.09.2025 02:51 โ€” ๐Ÿ‘ 2    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

Interesting read. I do enjoy surprises in sufficiently powered well conducted research as they often elucidate the presence of previously unknown mechanisms.

Regarding science reporting , I wish the article had direct citations for the studies and links to relevant publications.

17.09.2025 15:54 โ€” ๐Ÿ‘ 0    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

My desire to remain informed is at odds with my desire to remain sane.

16.09.2025 12:16 โ€” ๐Ÿ‘ 4    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

Your cutting edge comics are always on point.

14.09.2025 19:37 โ€” ๐Ÿ‘ 5    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

@grosscol is following 20 prominent accounts