Stem Cell Reports

Learn why Stem Cell Reports Early Career Editor Harsha Devalla values serving on the early career editorial team, and consider submitting an application to join! Applications are due 13 March. https://www.isscr.org/stem-cell-reports/#eceb ISSCR

Check out ISSCR's society journal, Stem Cell Reports!

I am delighted to share that I have been appointed as Early Career Editor for @stemcellreports.bsky.social, the official journal of the International Society for Stem Cell Research @isscr.org! 🔬🌍
I look forward to seeing your research in the field of stem cells!
Submit here: invt.io/1bxb9kpdtfj 👍

New research published in Stem Cell Reports! Histone methyltransferase Setd8 safeguards mouse retinal progenitor cell (RPC) identity by maintaining RPC-specific chromatin accessibility, thereby ensuring proper retinal development. https://ow.ly/Iql150Y6jaV

ISSCR

Expand your network and understanding of the editorial review process by serving as an Early Career Editor for ISSCR's open access, peer reviewed journal, Stem Cell Reports. Applications are due 13 March. https://ow.ly/xSe050XWaC6 Bruno Di Stefano

Online now in Stem Cell Reports! Human neuronal networks on micro-electrode arrays as a tool to assess genotype-phenotype correlation in CACNA1A-related disorders. https://ow.ly/ZIxE50Y1mut

Cell Press | The Gairdner Foundation | SickKids Foundation | ISSCR

New study from King's College London: Generation and characterization of iPSC models from HIV-1-positive individuals with divergent clinical outcomes. Resource supports lentiviral vector transduction and replicating HIV-1 studies https://ow.ly/s81Z50Y1m16

ISSCR | Cell Press

Ludovic Vallier, (Vallier Lab) Stem Cell Reports Associate Editor, is attending Biotherapy Days 2026 in Toulouse, France starting today! Connect with him to discuss whether your research is a fit for publishing in Stem Cell Reports!

Online now in Stem Cell Reports! Charting the translational pathway: ISSCR Best Practices for PSC-derived therapies. A comprehensive global framework guiding academia and industry through the translational pipeline and key decision points. https://ow.ly/orgU50Y1mle

ISSCR | Cell Press

Aging-associated changes in the composition of the microbiota result in reduced canonical Wnt signaling through Ascl2 in intestinal stem cells (ISC), which causes a decline in the regenerative potential of aged ISCs in vivo. https://ow.ly/Mh3x50Y1mc0

ISSCR | Cell Press

New #organoid research: Distinct SOX9 single-molecule dynamics characterize adult differentiation and fetal-like reprogrammed states in intestinal organoids https://ow.ly/b0H650Y1lRz

Cell Press | The Gairdner Foundation | SickKids Foundation | Universität Bayreuth

Meet Associate Editor Ludovic Vallier at the 4th Dubai Stem Cell Congress, February 7-8 2026. Connect with Dr. Vallier to discuss whether your research is a fit for publishing in Stem Cell Reports!

Aspartoacylase human iPSC-derived neural progenitor cells transplantation can effectively reverse established Canavan disease pathology, suggesting therapeutic potential for treating symptomatic patients https://ow.ly/2aAO50Y1lH1

The Gairdner Foundation | SickKids Foundation

Stem Cell Reports Early Career Editor Amy Wong 🇨🇦 shares how serving as an Early Career Editor for ISSCR's society journal has impacted her career. Applications are open now through 13 March to serve on the Stem Cell Reports Early Career Editorial team. Learn more: https://ow.ly/6L9850XWajH

Meet Early Career Editor Harsha Devalla at the New Cardiology: Engineering, Vascular, and Molecular Insights meeting in Heidelberg, Germany in February. Connect with Dr. Devalla to discuss whether your research is a fit for publishing in Stem Cell Reports!

New #xenotransplation research from KU Leuven: Aβ plaques induce local pre-synaptic toxicity in human iPSC-derived neuron xenografts. https://ow.ly/tFqn50XSA6e

ISSCR | Cell Press | The Gairdner Foundation | SickKids Foundation

New #organoid research! Differential synaptic signaling responses in human cortical organoids after photon & proton irradiation. Findings underscore distinct biological effects of spread-out Bragg peak protons & their potential impact on the developing brain. https://ow.ly/hGFW50XVBE5

ISSCR

Improvements to iPSC-based somatosensory disease models by generating and validating a genetic toolset to fluorescently label all or distinct (nociceptor, low threshold mechanoreceptor, and proprioceptor) somatosensory subtypes. https://ow.ly/bp0j50XSAgZ

Ludovic Vallier, Stem Cell Reports Associate Editor, is attending Biotherapy Days 2026 in Toulouse, France 28-30 January 2026. Connect with him to discuss whether your research is a fit for publishing in Stem Cell Reports!

Stem Cell Reports is calling for applications to serve on its editorial team as an Early Career Editor, a prestigious opportunity for outstanding, early-career scientists to help shape the future of stem cell publishing. The deadline to apply is 13 March 2026. https://ow.ly/8iiP50XWscj

New #cardiomyocyte research maps temporal alternative splicing regulation during cardiac regulation and uncovers altered splicing events in iPSC-cardiomyocytes, providing insights into the limitations of these models in cardiovascular research. https://ow.ly/kr4550XSzCS

New research from National Institute of Environmental Health Sciences: Rbm25 governs embryonic stem cell identity and fate through transcriptional regulation of pluripotency and epigenetic programs https://ow.ly/FNNw50XSznN

ISSCR | Cell Press | The Gairdner Foundation | SickKids Foundation

New research from UC Berkeley and NIH! Evidence for a latent activated stem cell state in which a subset of quiescent olfactory epithelial stem cells are epigenetically primed to support injury-induced regeneration. https://ow.ly/fkpG50XVBmo

The Gairdner Foundation | SickKids Foundation | ISSCR

Comparative lipidomics show that iPSC-derived microglia differentiation methods have a major impact on microglial lipidomes & warrant attention when studying #Alzheimers and neuroinflammatory processes involving lipids. https://ow.ly/aesW50XVB4Y

The Gairdner Foundation | SickKids Foundation | ISSCR

Chaperonin proteins CCT5 and CCT7 epigenetically restrict the transition from pluripotency to totipotency in embryonic stem cells, underlining the role of CCT5 and CCT7 in maintaining telomere integrity and regulating pluripotent state dynamics. https://ow.ly/13K950XSzcb

Transitioning from human primordial germ cells to embryonic germ cells. New research applies multi-omic profiling to resolve their pluripotent & epigenetic dynamics, providing new insights into potential mechanisms underlying human germ cell tumorigenesis. https://ow.ly/XhAs50XSz3Y

Hsp70-Bim as a potential therapeutic target for chronic myeloid leukemia (CML) stem cells. Inhibition of Hsp70-Bim blocks mitophagy, leading to differentiation of leukemic stem cells (LSC) and loss of quiescence & LSC self-renewal potential. https://ow.ly/ZHUU50XSyQL

Elevated Spy1 drives sustained expansion of neural stem cells, increases stemness characteristics, decreases differentiation, and increases susceptibility to oncogenic transformation. #neuralstemcells #braindevelopment https://ow.ly/c7AR50XSyaf

ISSCR | The Gairdner Foundation | SickKids Foundation

New research using ex vivo vibrissae explant and skin #organoids identifies IGF1R as a potential regulator of Merkel cell formation, which likely exerts its effects through the AKT pathway #skinorganoid https://ow.ly/zsgS50XS7sg

ISSCR | The Gairdner Foundation | SickKids Foundation | Cell Press

New review on hematopoietic #organoids summarizes recent progress in HO construction, explores their potential applications, & discusses opportunities & challenges in modeling human hematopoiesis & diseases in vitro. https://ow.ly/Ku0z50XS7fX

ISSCR | The Gairdner Foundation | SickKids Foundation

Anne Grapin-Botton, Stem Cell Reports Associate Editor, is attending the Organoids from stem cells to diseases modeling in Paris, France in January 2026. Connect with her there to discuss whether your research is a fit for publishing in Stem Cell Reports!