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Stem Cell Reports

@stemcellreports.bsky.social

For scientists. By scientists. The official journal of the @isscr.org | Editor-in-Chief: Janet Rossant, CC, PhD

169 Followers  |  67 Following  |  101 Posts  |  Joined: 20.02.2025  |  1.6851

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tRF-23 promotes osteogenic differentiation of hBMSCs & protects against bone loss in ovariectomized mice, providing a foundation for characterizing the pathogenesis of osteoporosis & seeking new therapeutic targets. https://ow.ly/ApFk50X5TMC

ISSCR | The Gairdner Foundation | SickKids Foundation

09.10.2025 14:15 β€” πŸ‘ 1    πŸ” 1    πŸ’¬ 0    πŸ“Œ 0

I will be at #NACFC25! Let’s connect and discuss how your research may be a good fit for the Stem Cell Reports journal!

08.10.2025 23:21 β€” πŸ‘ 1    πŸ” 1    πŸ’¬ 0    πŸ“Œ 0
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New #organoid research from Michigan Medicine uses a whole-transcriptomic approach to find that retinoic acid signaling guides the efficiency of inner ear organoid-genesis & governs sensory-nonsensory fate specification https://ow.ly/MtWn50X5TI8 ISSCR | The Gairdner Foundation | SickKids Foundation

08.10.2025 14:01 β€” πŸ‘ 1    πŸ” 1    πŸ’¬ 0    πŸ“Œ 0
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Early Career Editor Amy Wong (Amy Wong πŸ‡¨πŸ‡¦) is presenting at the upcoming North American Cystic Fibrosis Conference in Seattle, USA later this month. Connect with her to discuss whether your research is a fit for publishing in Stem Cell Reports!

08.10.2025 12:01 β€” πŸ‘ 0    πŸ” 1    πŸ’¬ 0    πŸ“Œ 1
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RNA-seq study maps iPSC-derived motor neurons with C9orf72, FUS, TARDBP or SOD1 mutations. Reveals early synaptic dysfunction & RBP dysregulation in ALS gene mutations. A key resource for #ALS pathogenesis. https://ow.ly/tAnL50X5ToH

ISSCR | The Gairdner Foundation | SickKids Foundation

07.10.2025 21:00 β€” πŸ‘ 1    πŸ” 2    πŸ’¬ 0    πŸ“Œ 0
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New study finds a miRNA-TF-mRNA regulatory network associated with cellular #senescence in #osteoporosis (OP). miR-22-3p-ESR1 axis drives OP development, offering a promising mechanistic foundation for future therapeutic strategies https://ow.ly/qEJ750X5Tah

ISSCR

06.10.2025 19:00 β€” πŸ‘ 1    πŸ” 1    πŸ’¬ 0    πŸ“Œ 0
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Check out ISSCR's society journal, Stem Cell Reports!

We're excited to share that our Director @bertiegottgens.bsky.social has joined the Editorial Board of Stem Cell Reports! @isscr.org Submit your stem cell-related research now: invt.io/1ixbug4i0lt

03.10.2025 16:17 β€” πŸ‘ 4    πŸ” 2    πŸ’¬ 0    πŸ“Œ 0

Our center director, Dr. Thomas Rando, is among the 13 distinguished researchers who have joined the Stem Cell Reports Editorial Board! πŸ“–

03.10.2025 17:19 β€” πŸ‘ 3    πŸ” 1    πŸ’¬ 0    πŸ“Œ 0

Congratulations to BU's Darrel Kotton, MD, who has joined 12 other distinguished researchers on the editorial board for Stem Cell Reports, the official journal of the International Society for Stem Cell Research.

03.10.2025 17:30 β€” πŸ‘ 2    πŸ” 1    πŸ’¬ 0    πŸ“Œ 1
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Check out ISSCR's society journal, Stem Cell Reports!

As a member of the editorial board for @stemcellreports.bsky.social, I am excited to share that we are looking for submissions in the field of stem cell research! I invite you to submit your work for consideration. invt.io/1bxb3we64y1 @isscr.org

03.10.2025 21:29 β€” πŸ‘ 7    πŸ” 3    πŸ’¬ 0    πŸ“Œ 0
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Check out ISSCR's society journal, Stem Cell Reports!

As a member of the editorial board for @stemcellreports.bsky.social, I am excited to share that we are looking for submissions in the field of stem cell research! I invite you to submit your work for consideration. invt.io/1bxbz2ji4db @isscr.org #stemcell #DevBio #hPSCs #regeneration

03.10.2025 21:42 β€” πŸ‘ 6    πŸ” 2    πŸ’¬ 0    πŸ“Œ 0
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Associate editor April Pyle is presenting at the 2025 Frontiers in Myogenesis Conference today in Oregon, USA. Connect with her to discuss whether your research is a fit for publishing in Stem Cell Reports!

06.10.2025 12:01 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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Join @stemcellreports.bsky.social and @bacell3d.bsky.social on 4 November to learn how organoid models are being used to study human development, infection, tissue dynamics, and cancer across various organ systems. Features Short Talk Winners! Register todayπŸ‘‰ bit.ly/4o46DzZ

03.10.2025 14:23 β€” πŸ‘ 4    πŸ” 5    πŸ’¬ 0    πŸ“Œ 0
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New Leiden University Medical Center study shows that mutant APOL1 affects mitochondrial function in podocytes and may open up avenues for designing targeted treatments for patients with AMKD. https://ow.ly/9bZY50X5SQr

ISSCR | The Gairdner Foundation | SickKids Foundation | Cell Press

03.10.2025 14:20 β€” πŸ‘ 2    πŸ” 1    πŸ’¬ 0    πŸ“Œ 0
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Stem Cell Reports welcomes new researchers to its Editorial Board. Their appointments reinforce the Board’s commitment to championing the journal, raising its global visibility, and ensuring rigorous, high-quality peer review. Read more: ow.ly/YicL50X5QJF

02.10.2025 21:32 β€” πŸ‘ 3    πŸ” 2    πŸ’¬ 0    πŸ“Œ 2
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New study evaluates hPSC metadata using FAIR (findable, accessible, interoperable, reusable) principles. Highlights role of national stem cell registries and biobanks and calls for stronger global collaboration to align stem cell infrastructures. https://ow.ly/J2I450X4lLr

ISSCR | Cell Press

02.10.2025 13:40 β€” πŸ‘ 2    πŸ” 1    πŸ’¬ 0    πŸ“Œ 0
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Human macula formation forms via two waves of RA suppression by CYP26A1, controlling cell cycle exit and cone subtype specification. FGF8 is not involved in macular formation, in contrast to other species https://ow.ly/4SHX50X4leb

ISSCR | Cell Press | The Gairdner Foundation | SickKids Foundation

01.10.2025 16:01 β€” πŸ‘ 1    πŸ” 1    πŸ’¬ 0    πŸ“Œ 0
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Associate editor April Pyle is presenting at the Aegean 6th International Conference on Stem Cells today in Crete, Greece. Connect with her to discuss whether your research is a fit for publishing in Stem Cell Reports!

01.10.2025 11:20 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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New research models an in vitro cortical network & shows that a proper excitatory/inhibitory ratio is required to develop synchronized network activity in mouse cortical cultures https://ow.ly/663A50X4mfa

Scuola Normale Superiore | ISSCR | Cell Press | The Gairdner Foundation | SickKids Foundation

30.09.2025 21:45 β€” πŸ‘ 5    πŸ” 2    πŸ’¬ 0    πŸ“Œ 0
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New study from @uclamcdb.bsky.social shows MECP2 loss in #Rettsyndrome neurons triggers DNA damage & senescence via #PARP1 dysregulation. Restoring PARP1 reverses neuronal defects; potential therapeutic target https://ow.ly/guLJ50X4k2P

UCLA Broad Stem Cell Research Center | ISSCR

30.09.2025 14:00 β€” πŸ‘ 2    πŸ” 1    πŸ’¬ 0    πŸ“Œ 0
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Online now! iPSC-derived hepatic #organoids reveal ICAM-1-IL-1Ξ² crosstalk supports hepatocyte proliferation. These organoids can be applied to model liver injury and stellate cell activation in vitro. ow.ly/Z8bu50WZsc6

@isscr.org
@gairdnerawards.bsky.social
@sickkidsvs.bsky.social

25.09.2025 16:04 β€” πŸ‘ 2    πŸ” 1    πŸ’¬ 0    πŸ“Œ 0
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Check out ISSCR's society journal, Stem Cell Reports!

Excited to present at the CSHL Cell Fate Conversions 2025 meeting! Connect with me there to discuss whether your research is a fit for publishing in @stemcellreports.bsky.social. invt.io/1bxba296yhc #cshldirect

25.09.2025 15:24 β€” πŸ‘ 4    πŸ” 2    πŸ’¬ 0    πŸ“Œ 0
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Drivers and implications of lineage-specific cancer-related mutations in human pluripotent and adult stem cells Jung and Benvenisty identify cancer-related mutations in about 18% and 41% of mesenchymal and neural adult stem cells, respectively. They demonstrate a lineage-specific profile of cancer genes correla...

New research highlights need for genetic screening in PSCs & adult stem cells. Cancer-related mutations found in mesenchymal (18%) and neural (41%) #stemcells. ow.ly/QqCv50WZryY

@hebrewuniversity.bsky.social @isscr.org @cellpress.bsky.social @gairdnerawards.bsky.social @sickkidsvs.bsky.social

24.09.2025 16:24 β€” πŸ‘ 1    πŸ” 1    πŸ’¬ 0    πŸ“Œ 0
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New #hematopoiesis research maps single-cell dynamics of endothelial-to-hematopoietic transition from iPSCs & integrates it with human embryo datasets to identify ligand-receptor interactions that drive developmental regulation. ow.ly/B1Tu50WZquR
@fredhutchprotons.bsky.social
@uwiscrm.bsky.social

23.09.2025 14:26 β€” πŸ‘ 2    πŸ” 1    πŸ’¬ 0    πŸ“Œ 0
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Checkout the new podcast on VEGF-induced HSC mobilization.
Listen here tinyurl.com/f5x5z3cf or wherever you get your favorite podcasts. For all the details, check out their paper tinyurl.com/4c4jn25k.

@isscr.org
@ucscscience.bsky.social

22.09.2025 19:51 β€” πŸ‘ 2    πŸ” 1    πŸ’¬ 0    πŸ“Œ 0
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Optimized signaling pathway-based culture conditions stabilizes canine iPSCs & improves differentiation potential, including differentiation into cardiomyocytes. Valuable resource for future #diseasemodeling cell.com/stem-cell-re...

@isscr.org
@ucdavisvetmed.bsky.social

22.09.2025 19:06 β€” πŸ‘ 2    πŸ” 2    πŸ’¬ 0    πŸ“Œ 0
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New research from @danafarber.bsky.social!
Satellite glial contact enhances differentiation and maturation of human iPSC-derived sensory neurons providing a better model for investigating human peripheral neuropathies #neuropathy #neuron #glia ow.ly/zv6X50WZpnh

@harvardmed.bsky.social @isscr.org

19.09.2025 15:07 β€” πŸ‘ 2    πŸ” 1    πŸ’¬ 0    πŸ“Œ 0
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Advances in intravital imaging of adult neurogenesis in mice Stem-cell-derived neurons are added throughout life in distinct areas of the mammalian brain. Here, we review recent advances using intravital imaging to study adult neurogenesis and discuss future di...

Our review on in vivo optical imaging of adult neurogenesis in mice is now out. :)
@stemcellreports.bsky.social

www.cell.com/stem-cell-re...

13.09.2025 08:08 β€” πŸ‘ 2    πŸ” 1    πŸ’¬ 0    πŸ“Œ 0
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Trophoblast stem cell derivation from naive & primed hPSC enables ELF5 functional analysis; ELF5 is dispensable for maintenance of hPSC-derived TSC-like cells. Provides transcriptional data & a new platform to model the placenta & study gene function. ow.ly/Y3gy50WVg3X

@isscr.org

12.09.2025 15:54 β€” πŸ‘ 2    πŸ” 2    πŸ’¬ 0    πŸ“Œ 0
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New study profiles the matrisome of skeletal muscle-resident cells and identified quiescent muscle #stemcells as key #ECM producers.β€―Injury shifts muscle stem cells from ECM production to remodeling and motility. ow.ly/2GZB50WVfNt

@isscr.org
@gairdnerawards.bsky.social
@sickkidsvs.bsky.social

11.09.2025 15:21 β€” πŸ‘ 1    πŸ” 1    πŸ’¬ 0    πŸ“Œ 0

@stemcellreports is following 20 prominent accounts