Cytosurge AG

🏆 Dr. Gabriel Giger @ethz.ch (2025 Origins Federation @harvard.edu PhD Prize) used #FluidFM for groundbreaking artificial #endosymbiosis research!
🎬 👇
His @nature.com paper: 56K+ accesses, 99th percentile impact️ https://go.nature.com/4jPwdYa
More customer #stories ▶️ https://bit.ly/4pMCxT3

#anniversary #crispr #crispr #celledit #fluidfm #crispr #celledit | CellEDIT Service #Anniversary Today, we celebrate The Nobel Prize awarded in 2020 to Emmanuelle Charpentier and Jennifer Doudna for developing #CRISPR‑Cas9 as a programmable gene-editing tool. Their breakthrough turne...

#Anniversary #CRISPR @nobelprize.bsky.social

www.linkedin.com/posts/celled...

4/
Thanks to the #BiotechnetSwitzerland team, #CSEM, University of Applied Sciences and Arts Northwestern Switzerland @fhnw.ch for organizing this nice event.

#DataScience #LifeSciences #SingleCell #SameCell #LiveSeq

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• Longitudinality: True cell-level data pairs, not correlations
• Causality: #Samecell trajectories reveal perturbation → effect
• Multimodality: Connects phenotype, context & function with transcriptome 👇

2/ Live-cell sequencing #Liveseq stands out in this regard and may exhibit just the opposite: small datasets, yet highly informative. 👇

Great insights from "Life Science Industry Meets Data Science 2025" #BiotechnetSwitzerland.
@dossola.bsky.social
One concept came up a few times: "Lots of Data ≠ Lots of Information". This rings especially true in #NGS and #scRNAseq, where massive datasets often yield vague correlations. 👇

Static snapshots → pseudotime inference misses fast/rare/non-monotonic transitions. #LiveSeq tracks the same living cell over time, real trajectories, not assumptions. Within-cell causality for drug resistance, differentiation, and stress responses. Reach out + #webinar 👇 QR codes below. #SingleCell

See you there!

Join our #webinar to learn more > events.teams.microsoft.com/event/06737e...

Ever wonder what the butterfly effect looks like in molecular biology? 🦋
With #LiveSeq you can follow the same living cell over time — from tiny molecular flutter to dramatic transformation.
From correlation ➝ causation.

#SingleCell #CellBiology #ButterflyEffect #MolecularBiology #Transcriptomics

EMT is heterogeneous; endpoint scRNA seq = correlation. Live seq + #FluidFM follows the same living cell over time—imaging + longitudinal RNA → causation. @institutcurie.bsky.social applies it to EMT in #TNBC (chemo, MET, future multi omics). Read: www.cytosurge.com/blog/company...
#SingleCell

Cytosurge and Lexogen Announce Live-seq Workflow Readiness Live-seq brings longitudinal, non-destructive cell sequencing to every lab, revealing new insights into cellular behavior

6/ LINKS in the announcement 👉 cytosurge.com/blog/press-r...

5/ Researchers are invited to an upcoming #webinar and encouraged to apply for Cytosurge’s Live-seq Access Program, which offers proof-of-principle studies for selected projects.💻 LINKS👇

4/ By preserving cell viability, researchers can repeatedly sample RNA from the same living cells, unlocking true longitudinal, time-resolved transcriptomics and causally linked molecular and phenotypic data for applications in #developmentalbiology, #cancerresearch, and #drugdiscovery.

3/ Developed through a year of joint effort, the workflow integrates Cytosurge’s #FluidFM® OMNIUM platform for minimally invasive cytoplasmic sampling, with #Lexogen’s LUTHOR HD kit for ultra-sensitive #RNAlibraryprep, plus comprehensive sequencing and data analysis support.

2/ This breakthrough enables labs of any size to repeatedly sequence the same living cells, directly observing how #geneexpression shapes cellular behavior over time. #singlecell

Cytosurge and #Lexogen announce that their integrated Live-seq workflow is now available to academic researchers and industry partners worldwide.

From collab to publication: #CellEDIT helped Dr. Siniuk @leibnizfli.bsky.social validate a p53 site KO in U2OS via vector-free intranuclear #CRISPR. @natgenet.nature.com (Jan 2025) reframes transcriptional interference, showing #CoCoProms as dynamic gene regulators. #FluidFM #SingleCell

Dr. Voorberg van der Wel @bprc-eu.bsky.social uses #FluidFM OMNIUM to target #hypnozoites, the dormant liver stage behind relapsing #malaria. #Singlecell nanoinjection/extraction + #Liveseq longitudinal RNA, with reduced animal use.
Customer stories playlist ▶️ https://bit.ly/4gwzbQ4

Stay ahead in single-cell research 🧬✨
• Real-time updates → Follow us
• Insights & events → Website
• Exclusive content → Newsletter: https://www.linkedin.com/newsletters/fluidfm-update-newsletter-7120776447593431041/

#LiveSeq #FluidFM #SingleCell #Transcriptomics #Webinars #Events

#ThrowbackThursday #TBT Our team swapped lab benches and desks for puzzles, trains, and lake views. The best part? Time together! 📸🌅

#TeamBuilding #TeamWork #LifeAtCytosurge #CompanyCulture #SummerEvent

Have a stubborn cell line? Let us know which ones you struggle with!

#FluidFM #CRISPR #GeneEditing #SingleCellEngineering #HardToTransfect #PrimaryCells #IntraNuclearInjection #RNP #CellEDIT @tobias-a-beyer.bsky.social

What it unlocks 👇

When viral delivery, lipofection, or electroporation fall short, CellEDIT’s FluidFM-based intra nuclear injection offers a different path: force-controlled nanopipettes place CRISPR RNPs directly into the nucleus of a single cell, gently, precisely.

#CellEDIT101 Chapter 4: Overcome the “hard” in hard-to-transfect cells

FluidFM Customer Stories: Real Research, Real Results - YouTube Discover how researchers around the world are pushing scientific boundaries with FluidFM technology. This playlist features authentic testimonials from leadi...

More customer stories ▶️ bit.ly/4mX11an

#CancerResearch #CoreFacility #MSKCC #SingleCell #LiveSeq #DrugResponse #mRNAExtraction

💬"Because our FluidFM system was housed in a core facility, we could assist many researchers. In particular, it allowed us to extract RNA from live cells to study gene expression changes without causing cell damage. This precision opened new doors for drug response studies at the #singlecell level."

At MSKCC, Dr. Kim: 🔬
- Set up FluidFM as a resource serving multiple research groups
- Enabled cytoplasm extractions to study gene expression without cell damage
- Supported drug response studies at #singlecell resolution

Dr. Young Hun Kim shares her experience establishing and operating FluidFM at the Molecular Cytology Core Facility during her time at @mskcancercenter.bsky.social 👇🎬

Day #2 #Symposium2050 #UZH