Maria Bohnert Lab

Yayyy 😊 @sfb1348.bsky.social

08.11.2025 13:22 — 👍 0    🔁 0    💬 0    📌 0

The next #DGZ Focus Workshop on #Cilia & #Centrosomes will take place November 25 (end of October is our DGZ meeting in HD). Join us for a great speaker line-up, and big thanks to David Mick @mick-lab.bsky.social & Dagmar Wachten @wachtenlab.bsky.social for organizing!

11.10.2025 12:54 — 👍 11    🔁 8    💬 1    📌 1

Lipid droplet growth is orchestrated by the seipin complex, which provides a structural platform for droplet nucleation and expansion. The microprotein adipogenin fine-tunes seipin’s conformation, remodeling its architecture to regulate lipid storage capacity. This modulation results in the formation of fewer but larger lipid droplets, revealing a key mechanism in lipid homeostasis.

Fat storage in the body relies on specialized structures called lipid droplets. In a new Science study, researchers identified the microprotein adipogenin as a regulator of adipocyte lipid droplet size, revealing a key mechanism in lipid homeostasis.

Learn more this week: https://scim.ag/4nFEGO7

06.11.2025 19:05 — 👍 73    🔁 21    💬 1    📌 2

Wonderful to see our paper on the #organelle signatures of #neurons and #astrocytes out in final form - congratulations, Shannon Rhoads and team!🎉 t.co/BPxKlbU6Ou

17.09.2025 17:37 — 👍 99    🔁 40    💬 6    📌 1

FSP1-mediated lipid droplet quality control prevents neutral lipid peroxidation and ferroptosis - Nature Cell Biology Lange et al. identify a lipid droplet quality control pathway in which FSP1 safeguards stored neutral lipids from lipid peroxidation, thereby preventing the induction of ferroptosis.

Excited to share our study out in @natcellbio.nature.com! Led by @mikelangelipid.bsky.social, we identify the first #LipidDroplet lipid quality control pathway: LD-localized FSP1 protects stored lipids from oxidative damage and prevents LD-initiated #ferroptosis.
www.nature.com/articles/s41...

29.10.2025 17:21 — 👍 115    🔁 38    💬 6    📌 1

Exciting question! Lipid droplets within one cell can have distinct surface proteomes and lipidomes. The answer may be linked to this phenomenon of lipid droplet heterogeneity. Shout-out to @for5815 “Lipid Droplet Heterogeneity” who are looking into these aspects of lipid droplet biology.

07.11.2025 15:20 — 👍 1    🔁 0    💬 1    📌 0

Thank you Mike 😁

07.11.2025 14:51 — 👍 0    🔁 0    💬 0    📌 0

The Myo2 adaptor Ldm1 and its receptor Ldo16 mediate actin-dependent lipid droplet motility Zhao et al. identify the molecular machinery for lipid droplet motility, consisting of the type V myosin Myo2, the Myo2 adaptor protein Ldm1, and its surface receptor Ldo16. They uncover a molecular l...

Proud to share our study on #LipidDroplet #Motility #Mitochondria #MembraneContactSite now in Cell Reports @cp-cellreports.bsky.social! Big thanks to @rwedlichsoldner.bsky.social, @flofroehlich.bsky.social, @ruferbus.bsky.social, Daniel Kümmel lab, Thomas Becker lab! www.cell.com/cell-reports...

07.11.2025 14:06 — 👍 19    🔁 9    💬 3    📌 1

Finally made it here as well 😊🥰

06.11.2025 13:51 — 👍 0    🔁 0    💬 0    📌 0

🎉 Huge congrats to Maya Schuldiner from the Weizmann Institute (Israel) for the 🏅 Otto Warburg Medal 2026!
Her work on how proteins find their way to organelles and how these organelles talk to each other has reshaped how we think about cells 🧬✨
#OWM #WeizmannInstitute @elsevierconnect.bsky.social

27.10.2025 09:28 — 👍 52    🔁 17    💬 0    📌 3