Greg Harrison

UChicago Microbiology is searching for tenured or tenure-track faculty working in host-pathogens interactions, viral and bacterial pathogenesis, and emerging infectious diseases. Come join our vibrant Department! microbiology.uchicago.edu
Apply here apply.interfolio.com/174404

Faculty Professor Associate - Full-Time | Vaughn Cooper We are recruiting Faculty microbiologists in three (3) different, complementary, and collaborative areas at the University of Pittsburgh associated with the School of Medicine. 1) Fundamental researc...

🚨 Microbiologists! We are recruiting Assistant / Associate Professors in 3 collaborative areas of our U. Pittsburgh School of Medicine.
1) MMG (my dept): fundamental research in med micro
2) Peds ID / I4Kids institute
3) Center for Vaccine Research
🔗 to all 3 w/info: www.linkedin.com/posts/vaughn...

Fantastic meeting! Heard about SO MUCH groundbreaking work and met so many incredible people! Such a great community 😃

Rich Losick’s Farewell Publication Reexamines a Molecular Biology Milestone - Harvard University - Department of Molecular & Cellular Biology Richard Losick, Maria Moors Cabot Professor of Biology, Emeritus in Harvard’s Department of Molecular and Cellular Biology, is about to publish what he describes as his “last paper”—though […]

Rich Losick’s Farewell Publication Reexamines a Molecular Biology Milestone 🧪 🧬 #AcademicSky #higherEd
www.mcb.harvard.edu/department/n... @cryptogenomicon.bsky.social @craigphunter.bsky.social @rachellegaudet.bsky.social @harvardmagazine.bsky.social @naoshigeuchida.bsky.social

Analysis of essential genes in Clostridioides difficile by CRISPRi and Tn-seq | Journal of Bacteriology Clostridioides difficile is an opportunistic pathogen for which better antibiotics are sorely needed. Most antibiotics target pathways that are essential for viability. Here, we use saturation transpo...

Analysis of essential genes in Clostridioides difficile by CRISPRi and Tn-seq | Journal of Bacteriology journals.asm.org/doi/10.1128/...

NEW: Don't ask too many questions, but...

NIH may not re-terminate the 900ish grants at issue in the main NIH lawsuits after all.

To the PIs of reinstated grants, SPEND NOW!

🧵 Here's what NIH is probably thinking. Bear with me:

Conservation of sporulation genes and a transmembrane-containing Spo0B variant in Paenibacillus Sporulation is a strategy employed by many bacteria to survive harsh environmental conditions. The genus Paenibacillus includes spore-forming species notorious for spoiling pasteurized dairy products ...

Here we show that >90% of Paenibacillus encode a unique Spo0B with a transmembrane domain! TM domain helps it interact with its phosphorelay partners. Congrats to @isabellalin.bsky.social who left for grad school this week and her mentor @cassidyprints.bsky.social! www.biorxiv.org/content/10.1...

Post a non-religious photo you think of as holy.

A novel two-component system controls vancomycin resistance in epidemic Clostridioides difficile The glycopeptide antibiotic vancomycin is the frontline treatment for C. difficile infection in the UK. There have been only sporadic reports of resistance in the clinic but testing is rare so the tru...

New preprint from us! The latest part of our C. difficile vancomycin resistance story. We identified a new two-component system (VnrRS) that can control expression of the vanG pathway - just needs one amino acid change

@buddlejess.bsky.social @brockhurstlab.bsky.social @claireyt.bsky.social

😔

We are hiring! The Dept of Microbiology and Molecular Genetics is looking for faculty at the Assistant or Associate professor level (tenure track). Please consider joining our vibrant microbiology and immunology community at the University of Pittsburgh School of medicine

Elio Schaechter was one of my heroes. His 1958 paper with Ole Maaløe and Niels Kjeldgaard (fondly known as “SMK”) is a North Star for so much work in my group. A wonderful scientist, great communicator, and a very kind person. May his memory be a blessing.

On Aug. 1, ASM & partner societies filed an expanded amicus brief with SCOTUS to defend scientific integrity & protect early-career researchers. The brief highlights the harm caused by NIH grant terminations, including canceling the MOSAIC program. asm.org/press-releas...

The CspC:CspA heterodimer transduces germinant and co-germinant signals during Clostridioides difficile spore germination. https://www.biorxiv.org/content/10.1101/2025.08.01.668244v1

Excited to share this collaborative study with @ritatamayo.bsky.social showing that E. faecalis influences C. diff morphology through the phase variable CmrRST system! This work was co-led by the amazing team of @ashleyweiss.bsky.social and Jilarie Santos-Santiago!

Excited to post our first S. aureus preprint on biorxiv! Big congrats to co-first authors, postdocs @anjali20anil.bsky.social and Rezia Braza, and really enjoyed the collaboration with @torreslab.bsky.social !

NIH Open Letter of Support — STAND UP FOR SCIENCE Add your name now!

NIH employees issued a declaration on June 9 highlighting the need for resources that NIH uses to protect the public, innovate science and research important health issues Americans are facing. Read the declaration and consider signing the support letter: www.standupforscience.net/bethesda-dec...

Enzymatic Activity of PBP1B Compensates for β-lactam Mediated Inhibition of PBP2 in Cells Overproducing ppGpp The alarmone (p)ppGpp (ppGpp) accumulates in response to starvation and other stress, leading to inhibition of multiple biosynthetic pathways and, at high concentrations, suppression of bacterial grow...

Joint effort from lab alumnus Dr. Sarah Anderson and her fantastic undergraduate Isabella Mack on #ppGpp mediated control of cell wall synthesis in E. coli and the consequences for #AMR now up on @biorxiv-microbiol.bsky.social

www.biorxiv.org/content/10.1...

This is shameful

Join the 22,339 people who have joined to support our NIH colleagues. Let's get this to 50,000 RT

ADD YOUR NAME: Sign the Open Letter in Support of NIH Staff Join the courageous and committed National Institutes of Health (NIH) public servants by adding your name now.

What does 18,000+ brave signatories look like standing together in massive solidarity with the #NIH heroes of the historic Bethesda Declaration??...

Find out by adding YOUR NAME to our #NIHLove letter here! -

actionnetwork.org/forms/add-na...

#StandUpForScience
#BethesdaDeclaration
#StopTrump

Thank you, @liztansposon.bsky.social !!

Here Are the Nearly 2,500 Medical Research Grants Canceled or Delayed by Trump (Gift Article) Some cuts have been starkly visible, but the country’s medical grant-making machinery has also radically transformed outside the public eye.

This is your health on MAGA.

Oops “its” not “it’s”! Every time 😭

In spite of the daily deluge of devastating news about science/the world, I’m excited to preprint some of my postdoc work (supported by an IRACDA grant-now terminated). Probing PBP1 function we uncovered unexpected features of the #Cdif #divisome 😄 We think it’s divisome could be a great drug target

Pride Month: Guerrino Macori Pride Month takes place annually during the month of June – honouring and celebrating those within the LGBTQIA+ community, recognising their ongoing fight for equal rights and acceptance. To…

It’s Pride Month! We’re celebrating the LGBTQIA+ community and their ongoing fight for equality. Last year, Irish Division & Members Panel member @guerrinomacori.bsky.social‬ shared a blog on why this month matters: microb.io/3X7vsAJ 🏳️‍🌈 #PrideMonth #LGBTQIA

The MAHA Report Has Been Updated With Fresh Errors One psychologist who is newly cited in the report said the updated reference misconstrues his research.

The MAHA repot has also cited an article of which I am first author wrongly
www.notus.org/health-scien...

The goal is plainly and literally to cut the number of people involved in basic science in the US by 70%

NSF, NASA and NIH budgets per year, inflation adjusted from 2000-2025 along with the proposed cuts. NSF includes research component only. Massive cuts across all sectors, well below support spanning 25 years.

How bad will it be? Catastrophic.

Proposed cuts to #NSF, #NIH, and #NASA will set the US R&D landscape back 25 yrs+, cause economic and job loss now, and undermine innovations to come.

But, this is the WH's *proposed* budget.

Speak up now before it is too late.

(inflation adjusted $-s below)