yoonji kim

Lithium deficiency and the onset of Alzheimer’s disease - Nature Lithium has an essential role in the brain and is deficient early in Alzheimer’s disease, which can be recapitulated in mice and treated with a novel lithium salt that restores the physiological level.

Nature research paper: Lithium deficiency and the onset of Alzheimer’s disease

go.nature.com/4ftdsb2

A genetically tractable non-vertebrate system to study complete camera-type eye regeneration Nature Communications - Accorsi et al. show that the apple snail Pomacea canaliculata has eyes similar to humans and can fully regenerate them. They then developed genetic tools to establish these...

Evolution’s eye game is wild, but mollusks take it to another level

CRISPR in apple snails gives us a new model to dissect how nature rebuilds complex organs like the camera-type eyes we humans possess

It turns out Evolution doesn’t just innovate, it rewinds, remixes, & regenerates

rdcu.be/ezw0t

Cell surface crowding is a tunable energetic barrier to cell-cell fusion Nature Communications - Cell-cell fusion is fundamental to physiological processes such as muscle formation and viral infection. Here, the authors show that the proteins embedded on the plasma...

Check out our most recent published paper in @natcomms.nature.com about the effects of cell surface crowding in cell-cell fusion: rdcu.be/ezCOF

Chromatin heterogeneity modulates nuclear condensate dynamics and phase behavior Nature Communications - Chromatin heterogeneity in the cell nucleus modulates the size, mobility, and formation of biomolecular condensates; decreasing chromatin heterogeneity correlates with...

Congrats to Jing @jesszhiyuezhao.bsky.social‬
& @dnamystrom.bsky.social‬ on cool manuscript!!! Reveals how cell nucleus is a heterogeneous material, w chromatin organization controlling formation & phase behavior of nuclear condensates. #CellBiology #Chromatin #PhaseSeparation rdcu.be/evWxR

Super excited for @dnamystrom.bsky.social ✨huge congrats and can’t wait for all the cool science and discoveries to come 🔎🥳💚💜

🥳💚💜💚💜🥳

If heterochromatin is really a liquid-like condensate, why is it not spherical?
We investigated whether mechanical interactions between a condensate and a fiber network can explain the variety of morphologies seen in phase-separated nuclear compartments
www.biorxiv.org/content/10.1...

Awesome paper alert! Learn about spectrum of chromatin condensate morphologies due to elastocapillary effects (no, liquids do not need to be spherical!), from amazing duo @dnamystrom.bsky.social & Hongbo Zhao, w/ important contributions from co-authors Jorine Eeftens, Mikko Haataja, Andrej Kosmrlj.

Princeton's new Omenn-Darling Bioengineering Institute is hiring! New building opening this Fall, & Princeton is an awesome place to live & do amazing research at intersection of engineering & life sciences. **Please spread the word*** bioengineering.princeton.edu/join/open.

Start of 2025 @mblscience.bsky.social Physiology course! This is the second year of Amy @gladfelterlab.bsky.social and I co-Directing this absolutely amazing and life-changing course: www.mbl.edu/education/ad...

🦟 Join us at the #VosshallLab @RockefellerUniv
and @HHMI as a postdoctoral scientist! We're seeking a creative individual who is enthusiastic about our research in mosquito neurogenetics.
Apply: hhmi.wd1.myworkdayjobs.com/en-US/Extern...

Some of our 2025 cool science>

Postdoctoral Scientist - Vosshall Lab Primary Work Address: 1230 York Avenue, New York, NY, 10065 Current HHMI Employees, click here to apply via your Workday account. We have an outstanding opportunity for a Postdoctoral Scientist to joi...

Join the #VosshallLab as a postdoctoral scientist. Fully funded, right here in New York City @rockefelleruniv.bsky.social
hhmi.wd1.myworkdayjobs.com/en-US/Extern...

Nucleoli as biomolecular bubble tea! Congrats to former Princeton ugrad Holly Cheng (now GS @MIT) ->Holly's senior thesis work, a close collab w Roggeveen Wang & @zs-biophys.bsky.social‬ &Stone. Come for the cool movies & stay for the viscoelasticity! www.pnas.org/doi/10.1073/pnas.2407423122

Our work on lipid domain pattern formation is now published in Soft Matter as part of the themed collection "Pioneering Investigators": pubs.rsc.org/en/content/a...

Grateful for my advisor Andrej Košmrlj for his mentorship, and for our collaborators for teaching us a lot about membranes!

Genome-wide mapping of mesoscale neuronal RNA organization and condensation Subcellular RNA organization can affect critical cellular functions. However, our understanding of RNA microenvironments, particularly biomolecular condensates, remains limited, largely due to a lack ...

What drives cytoplasmic mRNA organization? We created unbiased, genome-wide maps of mesoscale RNA-RNA spatial proximity, revealing impact of encoded protein function. Fantastic work from @lindsayabecker.bsky.social @sofiquinodoz.bsky.social @davidaknowles.bsky.social www.biorxiv.org/content/10.1...

✨🦟✨HOW DO MOSQUITOES HAVE SEX? ✨🦟✨

Join us for a wild journey into hidden female control, rapidly evolving stimulation devices, fierce species competition, and DEADLY MOSQUITOES!

www.biorxiv.org/content/10.1...

WOW!! A new pre-print rethinking how mosquitoes, the world's deadliest animal, mates. Amazing work from Leah @leahhouri.bsky.social (former PhD student in my lab) conducted in @leslievosshall.bsky.social's lab. Huge implications (see below) www.biorxiv.org/content/10.1...

Large-scale control over collective cell migration using light-activated epidermal growth factor receptors Programmable control over tissue movement is a fundamental challenge for tissue engineering and wound healing. Suh, Thornton, et al. discovered that a light-controlled EGF receptor controls long-range...

I'm so happy to report that our preprint on light-induced collective cell migration has now been published in Cell Systems! This project was a lot of fun and will be the basis for a lot of our ongoing & future work.

Princeton's Omenn-Darling Bioengineering Institute is looking for a Cell Engineering facility Director. A tremendous opportunity to join our growing community, in brand-new building & brand new Institute! Please spread the word!!! bioengineering.princeton.edu. puwebp.princeton.edu/AcadHire/app...

BIG NEWS! The Mosquito Cell Atlas preprint is live! 🦟🧬 My first senior author paper! Massive and accessible snRNA-seq dataset and a lot of cool mosquito biology. A true collaborative achievement! #MCA
biorxiv.org/content/10.1...
See @oliviagoldman.net thread here

Photos of Aedes aegypti female (left) and male (right). Numbers indicate location of collected tissues (listed in legend boxes). Photos by Alex Wild.

I am thrilled to present the Mosquito Cell Atlas! We analyzed 367K nuclei from 19 tissues in male & female mosquitoes, creating a comprehensive resource for vector biology & infectious disease research.

Plus we made some surprising discoveries! 🦟🧵

biorxiv.org/content/10.1...

1/n

Leslie Vosshall awarded the 2025 Scolnick Prize in Neuroscience - MIT McGovern Institute Today the McGovern Institute at MIT announces that the 2025 Edward M. Scolnick Prize in Neuroscience will be awarded to Leslie Vosshall, the Robin Chemers Neustein Professor at The Rockefeller Univers...

Kavli NSI @rockefelleruniv.bsky.social member & former Director Leslie Vosshall has been awarded the 2025 Scolnick Prize in Neuroscience for her groundbreaking work on the neural mechanisms of mosquito behavior. 🦟🔬

Congrats, Dr. Vosshall! 🎉 #Neuroscience #KavliNeuro
mcgovern.mit.edu/2025/03/03/l...

Senior Director - Scientific Officer Current HHMI Employees, click here to apply via your Workday account. The Howard Hughes Medical Institute (HHMI) advances the discovery and sharing of scientific knowledge to benefit us all. As a biom...

HHMI Science Department is hiring! We are looking for an outstanding immunologist/ cancer biologist to join our senior leadership team. Remote work eligible, 24 weeks a year onsite, possibility of running a small lab with HHMI support

@hhmi.bsky.social

hhmi.wd1.myworkdayjobs.com/External/job...

Really nice issue of RNA this month featuring many Perspective pieces on RNA in disease. rnajournal.cshlp.org/content/31/3...

Ancient origin of an urban underground mosquito Understanding how life is adapting to urban environments represents an important challenge in evolutionary biology. Here we investigate a widely cited example of urban adaptation, Culex pipiens form m...

Ancient origin of an urban underground mosquito www.biorxiv.org/content/10.1...

BuzzWatch: uncovering multi-scale temporal patterns in mosquito behavior through continuous long-term monitoring Understanding the temporal dynamics of mosquito behavior is essential for developing effective interventions against pathogen transmission. However, limited knowledge exists about the environmental, p...

Thrilled to share 'BuzzWatch', my post-doc work with Felix Hol and @lambrechtslab.bsky.social

➡️Filming mosquitoes in a cage with a €15 camera but for 700h(1month) revealed fascinating insights into their behavior⌛🦟🎥⏳

preprint🔍 doi.org/10.1101/2025...
DIY guide 🛠️ theomaire.github.io/buzzwatch
🧵⬇️

Attention all you fantastic and energetic student and postdocs!!!!!

Physiology: Modern Cell Biology Using Microscopic, Biochemical and Computational Approaches | Marine Biological Laboratory This course is at the forefront of new tools — molecular, computational, biophysical — as it prepares students to tackle emerging biological questions.

The deadline to apply for the MBL Physiology course is fast approaching, January 27th! Consider applying to this amazing, life-changing research discovery experience in Woods Hole! www.mbl.edu/education/ad...

Mysterious Blobs in Cells Are Changing the Way We Understand Life Tiny specks called biomolecular condensates are leading to a new understanding of the cell

Excited to see this (cover) article on condensates come out in Scientific American. Nice quotes from me and many folks in the field. www.scientificamerican.com/article/myst...

A flyer for the MBL's 2025 Physiology course

🔔Upcoming deadline!🔔

January 27 is the last day to submit applications to the MBL's 2025 Physiology Course. This seven-week lab course has educated generations of leading biologists and fostered groundbreaking discoveries.

Learn more: bit.ly/3BZSj9c
#ScienceStartsHere