Busquets-Garcia Lab

Very happy and honored that our ERASE project has been proposed to be funded by the @ageinves.bsky.social . 3 exciting years ahead to further investigate the brain substrates of emotion recognition in normal and pathological aging. #PID2024

The wildfire touching Marseille prevented me to be in the symposium, to share our project linking astrocytes, cannabinoid drugs and Alzheimer disease and to attend to the interesting @gliameeting.bsky.social ! I am sure the symposium conducted by @murphyroyallab.org has been a success!

Together with Ciaran @murphyroyallab.org, from the Université de Montreal, we are co-chairing today the Symposium "Understanding the roles of astrocytes in cognition and behaviour across the lifespan" in the @gliameeting.bsky.social in Marseille.

Recycle your poster, share your research! New #Neuroscience event at @researchmar.bsky.social

🗓️ July 24 ⏰15:15h 📍Marie Curie Room
👩‍🔬 Keynote by Dr. Sara Mederos (@sainsburywellcome.bsky.social)

🔗 Register: forms.office.com/Pages/Respon...

👉 researchmar.net/agenda/968

@bgarcialab.bsky.social

🧠 How does the brain make decisions based on indirect associations between stimuli?

🔬 A new @pnas.org study led by Dr. Busquets @bgarcialab.bsky.social (@researchmar.bsky.social)
sheds light on the role of the amygdala and cortical circuits

👉 researchmar.net/news/732/

@hospitaldelmar.bsky.social

Our postdoc @carlarduaso.bsky.social will show her postdoctoral results during the Poster session during the morning of Sunday 29th. (P1.7): Astrocytes in action: sex-, genotype-, and cannabinoid-dependent mechanisms in Alzheimer’s Disease.

Our PhD student @imanzanaressierra.bsky.social will show her PhD results during the Poster session during the morning of Sunday 29th. (P1.5): A new behavioral protocol to study positive psychotic-like states induced by Delta-9-tetrahidrocannabinol (THC) in mice.

Together with our postdoc Sílvia Castany, we will be chairing the Symposium "The immune mind: how immunity shapes mood and behavior" with very interesting talks by @murphyroyallab.org, @caromenard666.bsky.social, @agnesnadjar.bsky.social and Sílvia on Sunday 29th at 11:30h.

Heading to the @ebbsociety.bsky.social meeting in Bordeaux to enjoy 4 days in a fantastic city, meeting colleagues and friends and enjoying a great scientific program. Our lab will contribute showing our different research lines.

Our PhD Jose Antonio González Parra and postdoc Irene Ayuso are attending the European Social Club meeting in Coimbra. Today, during the poster session, we have shown our interesting results on the brain circuits controlling emotion recognition in mice. #socialbehavior #mousebehavior #neuroscience

Our results, performed in the @researchmar.bsky.social, may help understand how inferential learning circuits are altered in trauma-related or neuropsychiatric disorders.

Check out the full paper here: pnas.org/doi/10.1073/...

#Neuroscience #Learning #Amygdala #Rodents #Behavior

Finally, by manipulating LEC→BLA projections during odor-taste associations we show that this pathway is crucial for proper inferential responses.

🧠 These findings offer new insight into the circuits behind complex learning.

Using TRAP2 mice + chemogenetics + viral tracing we showed that:

✅ The basolateral amygdala (BLA) is activated and necessary during the encoding of odor-taste associations.

✅ The lateral entorhinal cortex (LEC) → BLA projections are engaged during this associations.

In our new paper published in @pnas.org, led by our PhD student Jose Antoni González Parra, we used a sensory preconditioning task to study how mice learn associations between odors and tastes and how they later use that information to guide behavior.

Did you ever wonder why we often feel ungrounded attraction or aversion by certain places, smells, or foods?
Our brain does that by infering value from indirect associations in a process called higher-order conditioning.

🧵Here’s what we found using an specific paradigm in mice:

💼 Becoming a PI – how to get funding 💶

🗣️  @bgarcialab.bsky.social, Mara Dierssen, @sdelcilab.bsky.social & @marcsuarezcalvet.bsky.social 

📆 June 3 - ⏰ 15:00 CET
 📍#PRBB Marie Curie room

ℹ️ Registration: bit.ly/careermonth25

Our paper is out as a reviewed preprint on @elife.bsky.social together with the reviewers' comments . We plan to address most of the constructive comments in the weeks/months.

Dorsal hippocampus mediates light-tone sensory preconditioning task in mice doi.org/10.7554/eLif...

New lab group photo with a seagull included! @bgarcialab.bsky.social @researchmar.bsky.social @prbb.org

Projecting neurons from lateral entorhinal cortex to basolateral amygdala mediate the encoding of incidental odor-taste associations Daily choices are determined by prior direct or indirect associations between low-salience cues and reinforcers. In this study, we used a mouse odor-taste sensory preconditioning task combined with ge...

And today, happy to share the second preprint from the lab: Projecting neurons from lateral entorhinal cortex to basolateral amygdala mediate the encoding of incidental odor-taste associations www.biorxiv.org/content/10.1...

Dorsal hippocampus mediates light-tone sensory preconditioning task in mice Daily choices are often influenced by environmental cues that are not directly linked to reinforcers. This process is known as higher-order conditioning and can be measured using sensory preconditioni...

Happy to share our new preprint from the lab: Dorsal hippocampus mediates light-tone sensory preconditioning task in mice
www.biorxiv.org/content/10.1...