Claire Martin

Les astrocytes jouent un rôle inattendu dans l’obésité En modulant l’activité des astrocytes dans le cerveau de souris obèses, des chercheurs ont montré que ces cellules influent sur la flexibilité cognitive et sur le métabolisme corporel.

www.pourlascience.fr/sd/biologie/...

Notre article dans The Conversation France : Ces cellules du cerveau qui pourraient aider à lutter contre l’obésité
#astrocyte

Striatal astrocytes modulate behavioral flexibility and whole-body metabolism in mice - Nature Communications Striatal neural circuits control reward-associated behaviors but the role of astrocytes is still unclear. Here, the authors show that chemogenetic manipulation of striatal astrocyte in mice restore ob...

New publication out
Led by Enrica Montalban, who did a fantastic work, our new paper demonstrate a role for striatal astrocytes in the context of diet-induced obesity in both metabolic and cognitive processes. Thanks to all the collaborators for their work!

www.nature.com/articles/s41...

Thank you so much for your visit to the lab, Ciaran! It was a pleasure to see such nice astrocyte data and discuss with you.

J'ai eu le plaisir d'animer un atelier sur l'anosmie pour l'association Anosmie.org pendant le festival "les chemins du parfum" dans le cadre magnifique de la Faculté de Médecine de @umontpellier.bsky.social
Un grand merci à Isabelle Parrot pour son accueil
#anosmie

Examining the biological causes of eating disorders to inform treatment strategies Nature Reviews Neuroscience - Recent years have seen a growth in our understanding of the biological drivers of eating disorders and their interactions with environmental and psychosocial factors....

Writing this was like any other act of love - awkward at the start, frustrating at times, but something to be proud of. Very grateful to Dr Kristi Griffiths for agreeing to take on this challenge with me for @natrevneuro.nature.com
www.nature.com/articles/s41...

Bonjour,

Avec 60 scientifiques de 54 institutions et 17 pays, nous avons réactualisé le suivi des indicateurs clés du changement climatique et de l'influence humaine jusqu'à fin 2024,
1/...

A food-sensitive olfactory circuit drives anticipatory satiety - Nature Metabolism The authors describe a sensory circuit involving the medial septum (MS), where MS glutamatergic neurons integrate food odours to prime satiety and regulate nutrient intake.

📢 🤩Excited to share our latest paper👃🧠! Huge thanks to the amazing first author @janice-bulk.bsky.social‬ and all co-authors, especially @andreas-t-schaefer.bsky.social and ‪@tobiasackels.bsky.social‬ 🙌! ‬‬
www.nature.com/articles/s42...

DREAM Olfactory Mixtures Prediction Challenge 2025 'DREAM Olfactory Mixtures Prediction Challenge 2025' (Synapse ID: syn64743570) is a project on Synapse. Synapse is a platform for supporting scientific collaborations centered around shared biomed...

With a contemporary smartphone, capturing, transmitting, and replicating sounds and visuals is a breeze, yet replicating scents remains elusive. If you want to change this, consider joining the 2025 DREAM Olfaction Challenge at www.synapse.org/Synapse:syn6....
@oldbap.bsky.social

🎉Congratulations #AChemS2025 Career Award Winners! Don't miss their award presentations tonight at 7 PM.

Astrocytes This book gathers methods essential for investigating the multifaceted roles of astrocytes in both physiology and pathological conditions.

Very happy to share several common protocols used in our lab for the second edition of the book "Astrocytes: Methods and Protocols"
@lewisholt.bsky.social @astroantho.bsky.social

Thanks @dibenedetto-lab.bsky.social for being a very patient editor!

link.springer.com/book/10.1007...

A hypothalamic circuit underlying the dynamic control of social homeostasis Nature - New data on brain-wide circuits centred around two interconnected hypothalamic neuron populations provide significant mechanistic insights into the emergence of social need during social...

Our latest findings on social behavior circuits is out: how does the brain responds to social isolation? Terrific work by @dingliu.bsky.social et al. uncovering a circuit with similar neural architecture as physiological needs (hunger, thirst, sleep..). Detailed thread soon.
rdcu.be/ebo63

13* 1/2 Un monde sans odeur : Jean-Michel Maillard, Président de Anosmie.org avec l'éclairage médical de Véronique Marché | Ausha Pour ce mois de février, j'ai souhaité mettre un coup de projecteur sur un handicap méconnu et souvent passé sous silence l'anosmie... Qu'est-ce que l'anosmie ? Ce mot vous rappelle peut-être vagu...

Un monde sans odeur : Jean-Michel Maillard, Président de Anosmie.org avec l'éclairage médical de Véronique Marché

podcast.ausha.co/sens-figure/...

Special Issue: Glial omics: Unraveling mechanisms in health and disease: Glia: Vol 73, No 3 Glia is the top neurobiology journal for research into glial cells (also called gliocytes or neuroglia). Articles cover all aspects of glial cell biology in health and disease.

#GliaPapers #GliaSpecialIssue
SPECIAL COVER

SPECIAL ISSUE: Glial omics: unraveling mechanisms in health and disease
onlinelibrary.wiley.com/toc/10981136...

Editorial Unboxing “Omics” in Glial Biology to Understand Neurological Disease here - onlinelibrary.wiley.com/doi/10.1002/...

The Effect of Olfactory Disorder (and Other Chemosensory Disorders) on Perception, Acceptance, and Consumption of Food People with changes in the overall sensory experience of food often complain of taste disturbances, although the problem is normally caused by the loss of aroma in the food (thus an olfactory disorder...

Alexander Fjaeldstad and I have a new chapter in the book Smell, Taste, Eat: The Role of the Chemical Senses in Eating Behaviour, edited by @LorenzoDStafford. Lots of great insights here.

From our chapter, it’s clear that smell loss and its impact on ingestion remain vastly underexplored."

Bluesky’s science takeover: 70% of Nature poll respondents use platform Roughly 6,000 readers answered our poll, with many declaring that Bluesky was nicer, kinder and less antagonistic to science than X.

Roughly 6,000 readers answered our poll, with many declaring that Bluesky was nicer, kinder and less antagonistic to science than X

https://go.nature.com/42tH8Ai

⚠️ Un poste de MCU en Maths-Info-Stats s'ouvre bientôt à Sorbonne Université pour rejoindre mon équipe (background computationnel et experience en analyse de données de neurosciences experimentales souhaités + qualification requise). Contactez-moi pour plus d'infos!

Please RP!

Join us February 19 from 11:00 AM - 12:00 PM ET for the next Career Networking Seminar on Unraveling Mechanisms Regulating Odor Receptor Expression in Health and Repression in Disease!

Register now registration is free: achems.org/web/seminars...

Sex differences in olfactory behavior and neurophysiology in Long Evans rats | Journal of Neurophysiology In many species, olfactory abilities in females are more acute than those in males. Studies in humans show that women have lower olfactory thresholds and are better able to discriminate and identify odors than men. In mice, odorants elicit faster activation from a larger number of olfactory bulb glomeruli in females than in males. Our study explores sex differences in olfaction in Long Evans rats from a behavioral and electrophysiological perspective. Local field potentials (LFPs) in the olfactory bulb (OB) represent the coordinated activity of bulbar neurons. Olfactory gamma (65–120 Hz) and beta (15–30 Hz) oscillations have been functionally linked to odor perception. Spontaneous and odor-evoked OB LFPs were recorded from awake rats at the same time for 12 days. Odors used included urine of both sexes and monomolecular odorants characterized previously for correlation of volatility with behavior and OB oscillations. Sampling duration in a habituation context, baseline gamma and beta power, and odor-elicited beta and gamma power were analyzed. We find that females sample odorants for a shorter duration than males (just over 1-s difference). Although baseline gamma and beta power do not show significant differences between the two sexes, odor-elicited gamma and beta power in females is significantly lower than in males. Neither sampling duration nor beta and gamma power in females varied systematically with day of estrus. We further verify that variance of these behavioral and physiological measures is not different across sexes, adding to growing evidence that researchers need not be concerned about often-claimed additional variance in female subjects. NEW & NOTEWORTHY Olfaction plays a large role in evolutionary processes. However, we know little about sex differences in olfactory bulb neurophysiology, and many scientists believe that females are more variable because of estrus. We show that female rats sniff odors for shorter durations than males and have lower power in neural oscillations related to cognition. Estrus was not related to variance in any measures. Finally, males and females show equal variance on these behavioral and physiological processes.

It's out! Awesome study by @kruthikamaheshwar.bsky.social.
We found that female rats sample for shorter times in odor habituation. Gamma and beta oscillations in the olfactory bulb are lower amplitude for females, but only during odor sampling. #ChemSenses #neuroskyence 🧪
doi.org/10.1152/jn.0...

After years of nice staining and images we're having troubles with cFos antibodies from Synaptic Systems 😪.
Do you have any suggestions for other anti-cFos for immunofluorescence on free-floating mouse brain sections?
Thanks 🙏

Proud of this society 🤩!
We really try to do our best to promote our young scientists because they are the present and the future of our field.

Mobilisons-nous pour défendre les sciences et l’université publique Plus d’un tiers des membres de l’Institut universitaire de France appellent à une mobilisation pour dénoncer le sous-financement de la recherche et l’enseignement supérieur publics et la remise en cau...

Avec plus de 280 collègues de l'IUF j'ai co-signé cette tribune.

"Mobilisons-nous pour défendre les sciences et l’université publique".

Si vous n'êtes pas abonnés n'hésitez pas à me contacter pour lire le contenu.

www.liberation.fr/idees-et-deb...

🎉 The #AChemS2025 Preliminary Program is now LIVE! 🎉

Get a sneak peek at what's in store and start planning your trip to Bonita Springs! 🌴✨

Check out the full details here: achems.org/2025/

#AChemS2025 #ChemicalSciences #BonitaSprings

A background in physics, and his own curiosity, have helped Dmitry Rinberg tackle the complexities of the neuroscience of smell. More on Rinberg sniffing out the mysteries of olfaction.

By Lina Zeldovich

www.thetransmitter.org/olfaction/sn...

Perceptual constancy for an odor is acquired through changes in primary sensory neurons Learning-induced changes in primary sensory neurons support concentration-invariant perception of an odor.

We have a fresh new paper!
The PhD project of the talented Mark Conway.

A learning-induced change in the sensitivity of olfactory receptor neurons enables consistent perception of an odor. #olfaction #neuroscience

www.science.org/doi/10.1126/...

« L’expérimentation animale n’est pas toujours nécessaire mais demeure indispensable » TRIBUNE. Dans une tribune au « Monde », un collectif de 2 829 chercheurs et universitaires, dont huit présidents d’université, dénonce les contrevérités avancées par des parlementaires pour taxer les ...

www.lemonde.fr/sciences/art...

Les #cellules #gliales sont à l’honneur dans la Lettre des Neurosciences qui vient de sortir !!!!
👉 www.neurosciences.asso.fr/lalettre/ind...

Imagine seeing a disease's impact on every cell in the body. Now, you can! We introduce MouseMapper, an AI tool to reveal system-wide disease perturbations. It reveals obesity-induced changes in facial nerves & body-wide inflammation 👉🧵https://biorxiv.org/content/10.1101/2024.08.18.608300v1.full.pdf

Could one envision a synthetic receptor technology that is fully programmable, able to detect diverse extracellular antigens – both soluble and cell-attached – and convert that recognition into a wide range of intracellular responses, from gene expression and real-time fluorescence to modulation..