Biancastella Cereser

Submissions are open for the EACR - @themarkfdn.bsky.social Postdoctoral Fellowships until 20 August!

This funding is awarded for a period of three years to support excellent postdoctoral researchers in laboratories throughout Europe 🌍

Learn more: eacr.org/eacr-fellows...

Effect of gluten and wheat on symptoms and behaviours in adults with irritable bowel syndrome: a single-centre, randomised, double-blind, sham-controlled crossover trial Many patients with irritable bowel syndrome (IBS) believe gluten or wheat triggers their symptoms. We compared symptomatic responses to wheat and glut…

#GastroEdPick Effect of gluten and wheat on symptoms and behaviours in adults with irritable bowel syndrome: a single-centre, randomised, double-blind, sham-controlled crossover trial. @lancetgastrohep.bsky.social www.sciencedirect.com/science/arti...

NEW content online!

📢 New genome for the Andean condor!
🦅A rare species — the world’s largest soaring bird — facing major threats like habitat loss, persecution & poisoning

🌎The work, led by IEGEBA (UBA-CONICET) with CNAG, opens new opportunities for its conservation

📎 onlinelibrary.wiley.com/doi/10.1111/...

Grateful to have been one of 30 women selected by @helloeacr.bsky.social to join the Women in Leadership workshop.
Highlights included a powerful keynote by Prof. Caroline Dive and an inspiring discussion with Prof. @johannajoyce.bsky.social, @msmelanoma.bsky.social, Elaine Mardis, and Erica Sloan.

… with the new bluesky user @anastasiaalataki.bsky.social ☺️

Representing Imperial and our amazing (imho) studies at the #EACR25 @helloeacr.bsky.social ! @ninamoderau.bsky.social Anastasia Alataki in Lisbon 🍷☀️🧬

Excited to be at #EACR in Lisbon with @ninamoderau.bsky.social and @anniebaker.bsky.social!!!
☀️🧬
Too much choice of excellent talks! #EACR2025 @helloeacr.bsky.social

Such interesting work! Congratulations to the entire team!

Single-cell transcriptomics uncovers that cell-to-cell communication controls p53 activation Conventional chemotherapy remains a cornerstone of cancer treatment and is highly effective in the adjuvant and neoadjuvant settings. However, therapeutic resistance, especially in the metastatic cont...

🚨 pre-print alert 🚨
Very excited to share our work on how chomotherapy affects cell-to-cell communication. If you are interesting in #p53, #DNAdamage, #scRNA-seq have a read! Thanks to all authors 🤩 @biorxiv-cancer.bsky.social

www.biorxiv.org/content/10.1...

One month left to register for the 2025 Early Career Researchers Conference!

In its fifth edition, this virtual conference has become a must-attend for early career researchers to discuss critical aspects of a scientific career in cancer research.

Don't miss it: eacr.org/conference/e...

Higher or Senior Scientific Officer in Sutton | The Institute of Cancer Research View details and apply for this Higher or Senior Scientific Officer vacancy in Sutton. Salary : Salary from 39,805 to 49,023 Reporting to: Prof Trevor Graham Duration of ...

Single cell whizz with green fingers for molecular genomics? Want to develop and apply new technologies for profiling #cancer #evolution? Like single cell WGS + ATAC: www.biorxiv.org/content/10.1...

Perhaps our senior scientific officer role is for you?

jobs.icr.ac.uk/vacancies/12...

@icr.ac.uk

Hoping that peer-reviewers don’t rely on AI to review these papers…. 😕

Clonal tracing with somatic epimutations reveals dynamics of blood ageing - Nature The discovery that DNA methylation of different CpG sites can serve as digital barcodes of clonal identity led to the development of EPI-Clone, an algorithm that enables single-cell lineage tracing through cellular differentiation at scale.

Nature research paper: Clonal tracing with somatic epimutations reveals dynamics of blood ageing

https://go.nature.com/43NOe1R

There are only a few more days left to secure the discounted early registration rate for the EACR 2025 Congress!

Don't miss this opportunity to join us in Lisbon this June for Europe's premier cancer research event, set to be bigger and better than ever before 🤩

2025.eacr.org/register

A redefined InDel taxonomy provides insights into mutational signatures - Nature Genetics This paper describes a framework for classifying small insertions and deletions from genomic data and applies it to a large dataset comprising seven tumor types. The analysis highlights new insertion ...

PAPER OUT!! 🥳🎉💃🏻🕺🏻💃🏻🕺🏻

A redefined InDel taxonomy provides insights into mutational signatures @NatureGenet

Brainchild of the amazing #GeneKoh
(Sir Jeffrey Cheah ECR)

Tweetorial below!! 👇

1/n

www.nature.com/articles/s41...

After a sold-out 2023 event, Goodbye Flat Biology has moved to a larger venue in Essen, Germany to make sure more of you can join us for what promises to be another fantastic event!

Join us for 3 days of excellent science and networking:
eacr.org/conference/g...

A phylogeny of the 7 ape genomes that have now been completed from "T2T", with Homer Simpson representing mankind.

A project five years in the making, we've now published complete "T2T" genomes for six additional ape species! It turns out that finishing (and analyzing) six genomes is slightly more work than one... doi.org/10.1038/s415...

Where do proteins go in cells? Next-generation methods map the molecules’ hidden lives Spatial proteomics is helping biologists to uncover how cells work by mapping where proteins operate.

If you want to understand how cells function, you have to work out what proteins interact with — and where

https://go.nature.com/4hYLaol

🌟 Exciting #PhD Opportunity! Join my lab in beautiful #Vienna. We are studying tumor-immune interactions in #metastasis using #singlecell and #spatial omics! ⏰ Apply by 04/25 bit.ly/3l7WMhs more infos 👉 winklerlab.org

What is vibe coding, should you be doing it, and does it matter? The rise of large language models like ChatGPT that can churn out computer code has led to a new term - vibe coding - for people who create software by asking AI to do it for them

Welcome to the era of "vibe coding", where people are using ChatGPT and other AI tools to help write code, even if they don't know anything about software.

Sometimes we need variety in our cancer sources, and we feel inspired by “slightly” older specimens of benign lesions in dinosaurs - our commentary on the advances of paleoproteomics is now out in Biology! 🦕
www.mdpi.com/3254540

Tumor-derived arachidonic acid reprograms neutrophils to promote immune suppression and therapy resistance in triple-negative breast cancer How tumor cells overcome anti-tumor immune responses and drive cancer recurrence is not well understood. Yu et al. demonstrate how therapy-resistant breast cancer cells synthesize and secrete arachido...

'Herein, we discover that TNBC cells surviving anti-PD-1 and chemotherapy treatment accumulate neutral lipids. Disrupting lipid droplet formation in cancer cells reverses resistance and mitigates the immunosuppressive microenvironment.'
#Immunology #Immunotherapy

Very interesting piece for anyone producing and sharing genomics data

Researcher in Computational Biology and Cancer Epigenetics  (275425) | University of Oslo Job title: Researcher in Computational Biology and Cancer Epigenetics  (275425), Employer: University of Oslo, Deadline: Monday, March 31, 2025

We are hiring! A 3-year Researcher in #Computational #Biology and #Cancer #Epigenetics in University of Oslo, Norway and co-supervised by @amathelier.bsky.social . You will be part of @cancelluio.bsky.social. We focus on #Sarcoma. Find out more and apply here: shorturl.at/gM1CG

Award details | Funding and scholarships for students | University of Exeter

We have a funded PhD position available in Exeter @exeter.ac.uk
Gene Regulation in Brain Development and Disease 🧬
Please share / repost

www.exeter.ac.uk/study/fundin...

We offer three new positions to join BCA Phase 0:
1. A full-stack developer to work on the BCA database with @ebi.embl.org
2. A senior research technician to develop sc methods
3. A bioinformatician to analyze new atlases with @sangerinstitute.bsky.social

Details below.

Please, share and repost.

The transcriptomic architecture of common cancers reflects synthetic lethal interactions - Nature Genetics Tumor cells upregulate compensatory buffering genes following tumor suppressor loss. These genes may represent new synthetic lethal partners that could be harnessed therapeutically.

We show transcriptomic buffering of tumour suppressor loss via syn. lethal genes is not anecdotal but a cancer hallmark. Buffering also seen in BRCAness, predicts penetrant syn leth effects and outcome. @icr.ac.uk @cancerresearchuk.org @breastcancernow.bsky.social www.nature.com/articles/s41...

Rita Levi-Montalcini defied fascism, which excluded her from university due to her jewish ancestry, by setting up a clandestine lab in her own bedroom. During 1940-42 she carried out experiments that set the foundations for her Nobel-prize-winning research a decade later.
nautil.us/a-lab-of-her...

Thank you to all participants and speakers at our virtual conference this week, The Systemic Consequences of Cancer! A fascinating range of sessions and flash talks from our poster presenters 👏