Happy about our new paper in Nature rdcu.be/eukUB
The GluA3 structure provides a framework for understanding this disease-prone glutamate receptor - novel interfaces will provide targets for modulator development
02.07.2025 07:24 — 👍 23 🔁 9 💬 0 📌 0
The 3rd Berlin Single Molecule Biophysics Course will run from 8th to 12th September at the HU-Berlin, Institute of Biology.
Learn about single channels, single molecule TIRF, theory and analysis. Apply by 7th July at bsmbc@icloud.com. Fee waivers and bursaries available.
! Please share widely !
05.06.2025 20:35 — 👍 30 🔁 28 💬 2 📌 4
Hopkins researchers use cryoEM microscopy to advance understanding of glutamate AMPA receptor action. Article link: www.oneneurojhu.org/2025/04/02/b...
02.04.2025 19:29 — 👍 7 🔁 4 💬 0 📌 0
Today!!! Support our trainees!! Register here: us02web.zoom.us/webinar/regi...
26.03.2025 14:49 — 👍 5 🔁 5 💬 0 📌 0
Congrats!!!
26.03.2025 18:52 — 👍 4 🔁 0 💬 1 📌 0
Here's our newest study: we reveal the molecular principles of neuronal excitation by glutamate, and how physiological temperatures influence this process.
www.nature.com/articles/s41...
www.nature.com/articles/d41...
Led by @anish-mondal07.bsky.social, published in @natureportfolio.nature.com
26.03.2025 16:29 — 👍 60 🔁 24 💬 4 📌 1
Nav1.7 structure and severe pain: join our next worldwide sodium channel seminar on March 25th by Goragot Wisedchaisri (Seattle, US) on the “Structural basis for severe pain caused by mutations in Nav1.7”
www.sodiumchannelseminars.org for link and infos. See you there!
#ionchannel #WSCS
17.03.2025 07:25 — 👍 9 🔁 2 💬 1 📌 0
Needed a break from the anti-science, anti-NIH administration. Dingle peninsula in Ireland.
19.03.2025 14:35 — 👍 3 🔁 0 💬 0 📌 0
The Channels, Receptors & Transporters Subgroup of the @biophysicalsoc.bsky.social is excited to announce the final program for our 2025 Symposium. Please join us on Feb 15 to hear from @willowcoyote.bsky.social @drcontrexin.bsky.social @corrylab.bsky.social and others 👇Thanks to our sponsors!
19.01.2025 23:01 — 👍 16 🔁 14 💬 0 📌 3
Direct visualization of electric-field-stimulated ion conduction in a potassium #ionchannel - Cell https://buff.ly/3WfbsLe
12.01.2025 11:39 — 👍 4 🔁 3 💬 0 📌 0
Our January issue is here ✨ https://buff.ly/3DFIr4N The cover shows agonist-induced #ionchannel opening of human NMDA receptors assayed using single channel outside-out patches to detect varied activation delays and failures. From Miaomiao He & @lwollmuth.bsky.social (https://buff.ly/3W6IQ6J).
06.01.2025 15:04 — 👍 11 🔁 6 💬 0 📌 1
I always said that I will not win a Nobel Prize because I like to drink. Well there goes that theory.
21.12.2024 02:33 — 👍 2 🔁 0 💬 1 📌 0
There is a postdoctoral position available in cryoET and FIB/SEM of Parkinson's disease available in at the Franklin!
See details here: opportunities.rfi.ac.uk/vacancy/post...
This work is in collaboration with our partners at MSD and their London Discovery Centre.
Please share!
20.12.2024 15:28 — 👍 19 🔁 8 💬 1 📌 0
Grateful for having contributed to this work by the Isabelle Baconguis group, who solved eleven (!) new structures of hASIC1a to show that open states require linear transmembrane helices, while desensitized states display a dazzling structural diversity
www.biorxiv.org/content/10.1...
#ionchannels
13.12.2024 13:47 — 👍 33 🔁 10 💬 3 📌 0
Dear ion channel community - come and join us for an exciting talk by @corrylab.bsky.social next Tuesday on sodium channel fast inactivation. Do you still believe in ball-and-chain? Or rather rings obliterating the pore? Something else? Then come and discuss with us at the #WSCS! #ionchannels #Nav
14.12.2024 15:15 — 👍 14 🔁 9 💬 1 📌 0
A good reason to bring out the brown alcohol. A former UG/MS student in the lab (far left. Now MD/PhD at Albert Einstein) stopped by for random visit. Others made the bad decision to work in my lab. Always fun.
14.12.2024 01:30 — 👍 4 🔁 0 💬 0 📌 0
Voltage and concentration dependence of Ca2+ permeability in recombinant glutamate receptor subtypes
You have to enable JavaScript in your browser's settings in order to use the eReader.
So receptors with only Glutamine (Q) present are permeable to potassium and sodium about equally well, and they actually prefer calcium. We show this in the preprint, others like @lwollmuth.bsky.social have shown this.
dx.doi.org/10.1113/jphy...
12/n
06.12.2024 11:05 — 👍 3 🔁 1 💬 1 📌 0
At McGill visiting Derek. Wonderful science here. Lots of synaptic physiology. Very elegant. #iglur. #ionchannels
05.12.2024 14:05 — 👍 7 🔁 0 💬 0 📌 1
Book rec: Neanderthal Man by 2022 @nobelprize.bsky.social laureate Svante Pääbo. A fascinating dive into sequencing ancient 🧬. Captures the thrills, setbacks, and Pääbo’s personal vulnerabilities during groundbreaking science.
02.12.2024 23:23 — 👍 52 🔁 6 💬 2 📌 0
Important article that challenges the classic view of axons as simple tubes. To what extent they fluctuate in diameter is up for debate - see some thoughts in this commentary piece in @science.org. Exciting time for axon scientists!
02.12.2024 10:33 — 👍 106 🔁 34 💬 5 📌 0
Happy to share our new review on the structural pharmacology of TRP channels!
Check out the supplementary table, which includes a list of all ligands, corresponding PDBs of complexes with TRP channels, and reported affinity values.
www.sciencedirect.com/science/arti... #ionchannel #TRPchannel (1/5)
01.12.2024 03:00 — 👍 28 🔁 7 💬 1 📌 1
Looks fantastic!!! Jealous of the resolution.
29.11.2024 21:28 — 👍 1 🔁 0 💬 0 📌 0
TRPM8 #ionchannel mutations Associated With Persistent Pain After Surgical Injury of Corneal Trigeminal Axons | Neurology Genetics
More from Waxman!
HT @rohacstibor.bsky.social
https://www.neurology.org/doi/10.1212/NXG.0000000000200206
29.11.2024 13:23 — 👍 3 🔁 1 💬 0 📌 0
Nav computer modelling as tool to understand fast inactivation: join us for the next worldwide sodium channel seminar given by Ben Corry on December 17th. More info on www.sodiumchannelseminars.org. Mark your calendar and join in! #ionchannels #WSCS
29.11.2024 17:43 — 👍 14 🔁 9 💬 0 📌 1
Join the LMB's PhD programme!
Applications now open for October 2025
Deadline 3rd December 2024
Considering a PhD in molecular biology?
There’s still time to apply to join the LMB in October 2024.
Applications close on 3rd DEC.
Visit our website for more info: www2.mrc-lmb.cam.ac.uk/students/int...
22.11.2024 16:00 — 👍 8 🔁 14 💬 0 📌 0
This is a wonderful paper with a ton of difficult single channel measurements on NMDA receptors in non-equilibrium conditions. Fundamental information, presented without hype and with care.
27.11.2024 20:08 — 👍 8 🔁 2 💬 0 📌 0
@jgenphysiol.bsky.social
Also the experience at JGP was fantastic. Several reviewers really had incredible suggestions that were very helpful.
24.11.2024 15:52 — 👍 2 🔁 0 💬 0 📌 1
News reporter at @sciam.bsky.social (posts are my fault). Book person, cat person, etc. Georgetown alumna, SHERP34. In NYC. Signal: mbartels.07. she/her http://meghanbartels.github.io/portfolio/
Scientist. Cook. Research Faculty at the University of Michigan. Membrane protein paparazzi. Dining enthusiast. Immigrant.
Scientist. Structure and function of cell-cell communication with a special interest in neurons & cryo-EM. All opinions are my own.
Neuroscientist. And more.
👩🔬Neuroscientist interested in cellular excitability/in vitro models-often found patching sensory or autonomic neurons. Postdoc at WolfsonSPaRC, King's College London | iPSC-neurons | patch clamp | ion channels| neuro-cardiac interactions
Laboratory of structural biology of macromolecular assemblies and cytoskeletal proteins at CSIR-CCMB, Hyderabad, India. Previously at Stony Brook University(2018-2021).
Psychiatrist, MD PhD, at Johns Hopkins studying synaptic plasticity in psychiatric disease
https://gerberlab.org/
Computational protein research group of Prof Ben Corry.
We love molecular dynamics and all kinds of membrane proteins including ion channels, transporters and immune receptors
~Posts by group members
Hi there! I’m a psychiatrist with a research hobby/obsession. I work with a lot of ideas of scale, from molecular biophysics to social dynamics. I keep my feed active, so say hello! Happy to chat!
The Channels, Receptors & Transporters Subgroup of the Biophysical Society promotes the exchange of ideas and information pertaining to the study of biological membranes.
Sensory neurobiologist fascinated by temperature sensitivity and ion channels from many species. TRPM8 | Cold-sensing | Cold-evoked behaviors | Assoc. prof. at University of Bucharest, Romania.
Neurobiologie pour commencer, psychiatrie pour continuer. Quelque part entre le CNRS et l'APHP.
https://www.sorbonne-universite.fr/portraits/marc-gielen
Preclinical biologist at small biopharmas following cool ion channel and receptor targets to neuro, renal, and immune indications. Likes electrophysiology (still), fine z-primes, and serial commas. Bostonian by choice (oof). He/him
Neurogeneticist, transposonophile, drosophilophile, eonophile, foodie, husband, father, kayaker, dog in training, #BLM, anti fascist. 🛑 the GENOCIDE! Free Palestine 🇵🇸!
Postdoctoral Fellow at Gereau Lab studying ion channel, pain and plasticity. Former Graduate student at Rohacs Lab. #DSPAN Scholar
