(p)ppGpp-dependent activation of gene expression during nutrient limitation | mBio Bacteria often experience nutrient limitation and, in response, attenuate energetically costly metabolic processes like protein synthesis. At the same time, however, they stimulate the expression of a subset of proteins that facilitate survival under ...

(p)ppGpp-dependent activation of gene expression during nutrient limitation

#mBio from Jonathan Dworkin

journals.asm.org/doi/10.1128/...

Man Charged With Assaulting Federal Agent With Sandwich in D.C.

Is it assault with a deadly weapon if the weapon is only deadly when eaten?

What caught my attention was the mention of yocH, which we showed a while back was a prkC regulated gene

did you ever try PrkC mutant?

Simultaneous measurements of translation rate and transcriptome in single bacterial cells by scTR-seq uncovers linked regulation within a specialized active cell population. https://www.biorxiv.org/content/10.1101/2025.04.22.649982v1

Cool work from the @jonathandworkin.bsky.social lab : new riboswitch-based in vivo (p)ppGpp reporter systems for Bacillus subtilis!

Bacillus subtilis MurJ and Amj Lipid II flippases are not essential for growth | Journal of Bacteriology The assembly of peptidoglycan (PG), the typically essential polymer that provides structural integrity to bacterial cells, begins with the synthesis of the Lipid II monomer in the cytoplasm and along ...

Bacillus subtilis MurJ and Amj Lipid II flippases are not essential for growth

#JBacteriol by Kiera Englehart & Jonathan Dworkin

journals.asm.org/doi/10.1128/...