Jeremy Borniger

A Quiet Policy Shift That Could Devastate American Science Why NIH’s sudden move to multi-year grant funding should alarm every principal investigator and university

A little known - but hugely consequential - part of the government’s changes to science funding:

open.substack.com/pub/sciencea...

Evil shithead.

T cell receptor cross-reactivity prediction improved by a comprehensive mutational scan database Banerjee et al. present a comprehensive T cell receptor cross-reactivity database and a hierarchical Bayesian framework to predict T cell receptor targets. Together, they reveal structural and biochem...

Check out how we tackled one of the fundamental challenges in immunology, out today @cp-cellsystems.bsky.social: www.cell.com/cell-systems.... Our major innovations are BATCAVE and BATMAN, two new players to get us closer to solving TCR-pMHC predictions!

May the odds be ever in your favor.
4% payline at the NCI.

www.cancer.gov/grants-train...

Neutrophils drive vascular occlusion, tumour necrosis and metastasis - Nature Neutrophils actively induce tumour necrosis, driving vascular occlusion, pleomorphic necrosis and metastasis.

I’m happy to share our latest work on tumour necrosis! During my time in the @megeblad.bsky.social lab, we found that tumour necrosis is not a passive phenomenon secondary to tumour growth, but an active phenomenon driven by neutrophils and NETs! Thread below: (1/13)
www.nature.com/articles/s41...

Prasad is UCSFs failure

YouTube video by National Institutes of Health (NIH) Director’s Desk: The Future of Animal Models in Research | NIH’s Dr. Nicole Kleinstreuer

A discussion of the use of animals in research.

www.youtube.com/watch?v=iSvk...

1/n

(Warning: Rant coming)

Fear and loathing on study section: Reviewing grant proposals while the system is burning As grants are canceled, delayed and subject to general uncertainty, participating in study sections can feel futile. But it’s more important than ever.

i wrote an essay for @thetransmitter.bsky.social about what it feels like to serve on an NIH grant review panel (study section) right now

www.thetransmitter.org/craft-and-ca...

immigration is good actually.

Visiting Santiago Ramon y Cajal’s house in Barcelona featuring @erikherzog.bsky.social , Charo Robles & Luis de Lecea :))) neuroscience pilgrimage

Former NOAA official Monica Medina says the scale of death and destruction from catastrophic flooding in Texas was "entirely preventable," faulting budget cuts for hampering preparedness.

"Many of those lost lives could have been saved if links in our disaster response chain hadn't been broken."

#chronobiologyGRC in Barcelona

ICE now has a budget bigger than the United States Marine Corps.

ICE now has a budget bigger than what we spend on biomedical research in America.

This is sociopathic to the extreme.

Nazi Germany did literally ban Nature:

"Articles are often published in the London weekly scientific journal Nature containing outrageous and vile attacks on German science and the national socialist state.

The journal must therefore be excluded from general use in the scientific libraries."

RFK Jr. Says AI Will Approve New Drugs at FDA 'Very, Very Quickly'

This is a catastrophe in the making

gizmodo.com/rfk-jr-says-...

Center of Rho ophiuchi cloud complex, 7.5h LRGB. #astrophotography

Congrats on a beautiful study!

We have already received many interesting abstracts for the Cancer Neuroscience EACR Conference in Bilbao, Spain....

...and we are looking forward to reading *yours*! 🧠🔬

📢 Abstract Deadline June 30th 📢

#cancerneuroscience #neuroscience #cancer @helloeacr.bsky.social

ICE Has Deported at Least 70 U.S. Citizens GAO confirms ICE deported U.S. citizens due to systemic failures — and the agency still doesn’t know how many more it’s wrongly targeting

Wow: ICE Has Deported at Least 70 U.S. Citizens

NYT story about Judge Young’s ruling

Peter Gleick Image courtesy of Curtis Lomax.

In Nature Human Behaviour, Peter Gleick calls on scientists who are able and willing to do so to speak out publicly against the Trump administration’s attack on science, and argues that although dissent carries risks, it is riskier to stay silent. go.nature.com/3FIV7cC 🧪

House approves Trump's request to cut funding for NPR, PBS and foreign aid The House has voted to cut about $9.4 billion in spending as President Donald Trump’s administration looks to follow through on work by the Department of Government Efficiency when it was overseen by Elon Musk.

BREAKING: House approves President Trump's request to cancel $9.4 billion in previously approved foreign aid and funding for NPR and PBS.

FULL clip of agents throwing Sen. Alex Padilla to the ground and handcuffing him.

Officers threw him and held him to the ground even while he is seen as not resisting.

Footage from Sen. Padilla’s staff

It’s completely insane that US troops are illegally deployed to suppress domestic opposition and it’s not uniformly condemned by the press and political elite.

Pretending it does not exist will not alter reality. 🧪🔌💡☀️💨🔋

Don’t miss our latest 📝 with @chrislisgaras.bsky.social & Rick Staba on high-frequency oscillations in preclinical 🧠 disease models, with guidelines for recording, detection and analysis. journals.sagepub.com/doi/10.1177/...

Confirmed protest sites

Mass protests planned for June 14, everyone hit the streets. Every city, every capital. Resist and defend. #3E #HandsOff #Indivisible #FiftyFiftyOne #StopICE #NoKingsProtest

Find a confirmed location here (more protests exist but are not listed): nokings.org#map

Supreme Court allows DOGE team to access Social Security systems with data on millions of Americans The Supreme Court is clearing the way for the Department of Government Efficiency to access Social Security systems containing personal data on millions of Americans.

The Supreme Court allows DOGE to access Social Security systems containing personal data on millions of Americans.

Feroze is the definition of hero

Straight up Gestapo.