Dafne Campigli Di Giammartino

🚨For chromatin, epigenetics and non-coding RNA lovers: only two more weeks left to apply!

Check out our lab page and if interested don't hesitate to apply 3d-chrom.iit.it

Research Technician
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Senior Researcher-Technologist
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29.09.2025 14:10 — 👍 1    🔁 0    💬 0    📌 1

🎯 Our lab at the Italian Institute of Technology 3d-chrom.iit.it has a technician position available

If you are a scientist, interested in chromatin 🧬 epigenetics and non-coding RNAs and you are looking to work in a stimulating environment don’t hesitate to apply
👇
app.ncoreplat.com/jobposition/...

04.08.2025 14:41 — 👍 2    🔁 0    💬 0    📌 0

🚨 Last Call for Applications! 🚨
If you're passionate about chromatin 🧬 and non-coding RNAs, you have only a few days left to apply:

Three fully-funded positions in my lab to study the cross-talk between epigenetics and 3D chromatin architecture.

Application links are available in the post below 👇

27.03.2025 09:47 — 👍 1    🔁 1    💬 0    📌 0

I am so happy to see this work finally out 🎉 authors.elsevier.com/c/1kqIJ_Oylr...

Thanks to all the authors for the incredible teamwork!!!

27.03.2025 09:43 — 👍 4    🔁 1    💬 1    📌 0

To all chromatin and RNA enthusiasts 🧬 🧬 🧬

Our lab 3d-chrom.iit.it has several openings!

Looking for a well-paid position in a stimulating environment?

Apply here 👇

Senior Bioinformatician
iit.taleo.net/careersectio...

Senior Molecular Biology Researcher
iit.taleo.net/careersectio...

27.02.2025 16:05 — 👍 3    🔁 3    💬 0    📌 1

Deletion of a single CTCF motif at the boundary of a chromatin domain with three FGF genes disrupts gene expression and embryonic development Chromatin domains delimited by CTCF can restrict the range of enhancer action. However, disruption of some domain boundaries results in mild gene dysr…

Here is the peer-reviewed version of our study showing how some TAD borders are essential for gene regulation and development.

Loss of a single CTCF motif is sufficient to cause embryonic lethality.

www.sciencedirect.com/science/arti...

26.02.2025 21:21 — 👍 134    🔁 40    💬 8    📌 1

Post-mitotic transcriptional activation and 3D regulatory interactions show locus- and differentiation-specific sensitivity to cohesin depletion Prior studies showed that structural loops collapse upon acute cohesin depletion, while regulatory enhancer-promoter (E-P) loops largely persist, consistent with minimal transcriptional changes. Howev...

New preprint from the lab investigating the role of cohesin in the establishment of chromatin loops and transcriptional programs after cell division or during cell fate transitions. Study led by @ukjinlee.bsky.social. Grateful to the whole team and NIH for support!

24.02.2025 23:27 — 👍 25    🔁 11    💬 1    📌 0

Enhancer Mechanics and Enhanceropathies Join us for the highly anticipated third EMBO workshop on Enhancer Mechanics and Enhanceropathies! Building on the success of our previous meetings in Santander (2021) and Marseilles (2023), this eve…

Together with @smandrup.bsky.social and Minna Kaikkonen we are happy to announce the 3rd Edition of the EMBO Workshop on #Enhancers and #Enhanceropathies. This time we will meet during the beautiful Danish summer (June 16-21).

Book the dates and register soon!!!

meetings.embo.org/event/25-enh...

31.01.2025 14:35 — 👍 57    🔁 33    💬 0    📌 7

Very cool collaboration with @andersshansen.bsky.social's lab on how to calibrate Micro-C using our labs' previous live-cell estimates of looping probability!

17.01.2025 13:18 — 👍 14    🔁 3    💬 1    📌 0

Enhancer scrambling strategy

We are happy to share our enhancer scramble story, a strategy to create hundreds of stochastic deletions, inversions, and duplications within mammalian gene regulatory regions and associate these new architectures with gene expression levels 🧵
www.biorxiv.org/content/10.1...

15.01.2025 20:32 — 👍 182    🔁 77    💬 3    📌 2