Dana Fakhreddine

Hierarchical lineage architecture of human and avian spinal cord revealed by single-cell genomic barcoding The formation of neural circuits depends on the precise spatial and temporal organisation of neuronal populations during development. In the vertebrate spinal cord, progenitors are patterned into mole...

Thrilled to share my main postdoc work with @jamesbriscoe.bsky.social

We used genomic barcoding + scRNAseq in chick & human embryos to reveal a lineage architecture that reshapes how we understand neural tube development & cell fate decisions
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www.biorxiv.org/content/10.1...

Of all the wild things that could have happened on viva day, I never expected to be in a badge-off with Paul Nurse 🤣

It has been a pleasure and a privilege being @cohouart.bsky.social and @zenahadjivasiliou.bsky.social's joint PhD student!
Can't wait for what's next!

Another week, another Houart lab image🔬

This week, it's a 3D image of a multiplex, in-situ of a chick forebrain by @danafd.bsky.social who studies early forebrain development in vertebrates & uses HCR to show the expression patterns of gene products instrumental in pallial/subpallial specification.

This week's image is by @joseriveraz.bsky.social who's tracing the lineage of progenitors in the human developing cortex.

Here, José shows the building blocks of the developing cortex at 10pcw with SOX2 (apical progenitors), CTIP2 & TBR1(neuronal markers), NESTIN (radial glial fibers), and DAPI.

It has been an absolute pleasure for our lab to attend #ECCN2025 for the first time this year.

We had meaningful discussions and learned a lot from a vibrant community tackling tough questions on brain evolution and development! Super excited for what lies ahead!

This is probably the coolest conference poster I've ever seen.