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Grocott Lab

@grocottlab.bsky.social

Dr Tim Grocott's research group, University of East Anglia UK. 🐣 embryology & new adventures in human development via stem cells. Modelling in silico/vitro. Fascinated by signalling networks, patterning, all things early development and the eye.

1,914 Followers  |  2,167 Following  |  16 Posts  |  Joined: 07.10.2023  |  1.8273

Latest posts by grocottlab.bsky.social on Bluesky

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I am SO incredibly excited to announce the launch of a global list of Inspiring Black Scientists. You can use this list to nominate and connect with researchers. Please share and join us in highlighting these outstanding scientists for #BlackHistoryMonth and beyond!

www.wiley.com/en-us/resear...

05.02.2026 17:36 β€” πŸ‘ 134    πŸ” 78    πŸ’¬ 3    πŸ“Œ 8

The frustrating thing about working with people who do not understand the scientific method is when they want you to prove their hypothesis... What they want to believe.

The way science *SHOULD WORK* is that you form a hypothesis and then work like hell to try and break that hypothesis.

04.02.2026 20:45 β€” πŸ‘ 19    πŸ” 5    πŸ’¬ 1    πŸ“Œ 0

The University of Sheffield is hiring:
Research Associate in Developmental Biology

02.02.2026 21:59 β€” πŸ‘ 2    πŸ” 1    πŸ’¬ 0    πŸ“Œ 1
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This developing quail embryo looks like it's thinking fiery thoughts for #FluorescenceFriday 🐣πŸ”₯πŸ§ͺ. Imaged by the fantastic @vanderspuy.bsky.social

30.01.2026 03:34 β€” πŸ‘ 91    πŸ” 18    πŸ’¬ 0    πŸ“Œ 1
A cartoon with a woman in a labcoat looking in a microscope saying "The best part of science is knowing, for a moment, something that nobody else in the world knows."

A cartoon with a woman in a labcoat looking in a microscope saying "The best part of science is knowing, for a moment, something that nobody else in the world knows."

Still true

27.01.2026 15:38 β€” πŸ‘ 41    πŸ” 9    πŸ’¬ 0    πŸ“Œ 3
Neural crest cell-derived DKK1 and NEDD4 modulate Wnt signalling in theΒ second heart field to orchestrate outflow tract development - Nature Communications Neural crest cells have been implicated in heart development, yet the mechanisms by which they act have remained elusive. Here, the authors show neural crest cells modulate Wnt signalling in cardiac p...

Excited to share our recent publication in which we identify new roles for neural crest cells in directing heart development, and new pathological mechanisms underpinning congenital heart disease!

www.nature.com/articles/s41...

27.01.2026 23:58 β€” πŸ‘ 1    πŸ” 1    πŸ’¬ 0    πŸ“Œ 0

These are one of the many ways @biologists.bsky.social and its flagship journals support our community. Take advantage of them and then consider publishing with there, rather than in the fifth step-down journal of the robber barons

23.01.2026 12:17 β€” πŸ‘ 15    πŸ” 7    πŸ’¬ 0    πŸ“Œ 0
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Job alert🚨I am advertising a 2-year postdoctoral position to work on the mathematics of plant morphogenesis @mpipz.bsky.social. Candidates with interests in mathematical modelling, mechanics, or biophysics are strongly encouraged to apply. 🌱Reposts are appreciated!

jobs.mpipz.mpg.de/jobposting/4...

22.01.2026 14:34 β€” πŸ‘ 26    πŸ” 27    πŸ’¬ 0    πŸ“Œ 2
Identifying enhancers in the chicken embryo.

Identifying enhancers in the chicken embryo.

#DBfeature 🐣

With the rise of omics data, identifying tissue-specific enhancers is easier than everβ€”but validation is key. Ruth M. Williams discusses why the chicken embryo is the ideal in vivo sandbox for testing human regulatory elements in our recent review.
www.sciencedirect.com/science/arti...

22.01.2026 14:53 β€” πŸ‘ 5    πŸ” 2    πŸ’¬ 0    πŸ“Œ 0

The amount of truly stunning retinal research in avians coming out of Europe lately is making me jealous.

Such cooooool work.

22.01.2026 16:27 β€” πŸ‘ 22    πŸ” 5    πŸ’¬ 0    πŸ“Œ 0

I learned dynamical systems theory for the embryos, I learned PDEs for the embryos, I’ll learn stat mech for the embryos, I learned Julia for the embryos, might need to learn Java for the embryos … 80% of what I read is for the embryos …

17.01.2026 01:53 β€” πŸ‘ 27    πŸ” 2    πŸ’¬ 3    πŸ“Œ 0
Excitation and emission spectra

Excitation and emission spectra

mSumireF a Monomeric Violet Fluorescent Protein:
pubs.acs.org/doi/full/10....

08.01.2026 18:15 β€” πŸ‘ 17    πŸ” 5    πŸ’¬ 0    πŸ“Œ 1

There is still over a week left to apply.
Please send your documents to maik.bischoff@uni-muenster.de

06.01.2026 12:43 β€” πŸ‘ 14    πŸ” 9    πŸ’¬ 0    πŸ“Œ 0
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Marr's three levels for embryonic development: information, dynamical systems, gene networks Developmental patterning comprises processes that range from purely instructed, where external signals specify cell fates, to fully self-organized, where spatial patterns emerge autonomously through…

Throughout this work, we found it really helpful to organize our thinking along 'Marr's three levels of analysis':
1. the computational problem
2. the algorithmic solution
3. biophysical implementation

Check out our review laying out this conceptual framework here: buff.ly/NE4JEOA

05.01.2026 08:00 β€” πŸ‘ 15    πŸ” 7    πŸ’¬ 1    πŸ“Œ 0
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How can cells use information from neighboring cells to improve the spatial precision of morphogen patterns? πŸ€”

We show that cells can gain positional information by "talking" to their neighbors - how much depends critically on spatial correlations of the patterns.

buff.ly/w56OUJT

05.01.2026 08:00 β€” πŸ‘ 47    πŸ” 12    πŸ’¬ 1    πŸ“Œ 0

@devdynamics.bsky.social Welcome to Bluesky Developmental Dynamics, added to the Developmental Biology starter pack II.

You can also patch in to more #DevBio folks by checking out the first Developmental Biology start pack here:

go.bsky.app/M5AgJhn

16.11.2024 23:20 β€” πŸ‘ 89    πŸ” 41    πŸ’¬ 29    πŸ“Œ 2

Morphogenesis & Organogenesis!
Part 1 (full) in the comments πŸ‘‡

Comment if you'd like to be added (regardless of age or career stage!)

Please post your own biology-related starter packs using #BioStarterPacks

πŸ§¬πŸ”¬πŸͺ°πŸŸπŸπŸŒ±

26.06.2025 21:40 β€” πŸ‘ 35    πŸ” 21    πŸ’¬ 18    πŸ“Œ 1
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β€œThis work highlights how dynamical systems theory and nonequilibrium thermodynamics provide powerful analytical techniques to study biological complexity.”

iopscience.iop.org/article/10.1...

21.12.2025 03:40 β€” πŸ‘ 1    πŸ” 1    πŸ’¬ 0    πŸ“Œ 0

This is now a published peer-reviewed paper, in which we show, for the first time (to my knowledge) an interaction and co-operation between SALL4 and BAF (SWI/SNF). Together, they induce neural crest fate early on, by priming thousands of enhancers in the neuroectoderm.
doi.org/10.1242/dev....

19.12.2025 12:48 β€” πŸ‘ 33    πŸ” 14    πŸ’¬ 3    πŸ“Œ 0
Vascular development in the early chick embryo

Vascular development in the early chick embryo

#DBfeature 🐣

Unravelling early hematoendothelial development through the chick model: Insights and future perspectives

by Lydia Pouncey, Gi Fay Mok @gifaymok.bsky.social

www.sciencedirect.com/science/arti...

18.12.2025 14:53 β€” πŸ‘ 11    πŸ” 4    πŸ’¬ 0    πŸ“Œ 0

I've spent all day struggling to write a single page of a popular science article. I bang away at a word processor; give up; start diagramming on paper. Take some notes; draft a few sentences in pen; return to the computer...and very slowly I figure out what I was trying to say in the first place.

16.12.2025 23:41 β€” πŸ‘ 499    πŸ” 73    πŸ’¬ 11    πŸ“Œ 23
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UK to rejoin EU’s Erasmus student exchange programme Exclusive: British students will be able to participate in EU-wide scheme from January 2027, sources say

Thank goodness for that. Something that shouldn’t have happened, happened. And now it’s set to unhappen. Great for students, great for research in general and great for Britain.
www.theguardian.com/world/2025/d...

17.12.2025 08:19 β€” πŸ‘ 898    πŸ” 154    πŸ’¬ 21    πŸ“Œ 10
Medfly

Medfly

UEA campus

UEA campus

Please share πŸ“’

We have a Postdoc position available here @uniofeastanglia.bsky.social to develop innovative genetic control strategies for insect agricultural pests in collaboration with @imperialcollegeldn.bsky.social

vacancies.uea.ac.uk/vacancies/19...

15.12.2025 09:35 β€” πŸ‘ 22    πŸ” 27    πŸ’¬ 0    πŸ“Œ 1
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Keeping up with the neighbours: local synchronisation of cell fate decisions during development - EMBO Reports Even before the advent of multicellular life, unicellular creatures would communicate with their neighbours to coordinate their behaviours. Multicellular organisms have the particular challenge of orc...

Hello, here is a review I wrote about how cells sometimes try to synchronise with surrounding cells so that they can do a good job of building tissues during development. It is called "Keeping up with the neighbours"

link.springer.com/article/10.1...

#DevBio πŸ§ͺ

11.12.2025 15:19 β€” πŸ‘ 58    πŸ” 18    πŸ’¬ 0    πŸ“Œ 2
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At first glance, looks like a Gray–Scott reaction-diffusion

But it’s a fertilized starfish πŸ₯š: proteins self-organizing into spiral waves across the membrane

Same dynamics seen in ❀️/🧠/🌊, even quantum fluids. Universality in action!

#ComplexSystems

news.mit.edu/2020/growth-...

09.12.2025 21:03 β€” πŸ‘ 60    πŸ” 24    πŸ’¬ 0    πŸ“Œ 2
An image of a whole frog eye that has been labelled with a photoreceptor marker (cyan) and a nuclear marker (orange). The retinal is the striped tissue and the lens is the large round tissue with the orange interior. You can also see the optic nerve at the top middle of the picture (12:00).

An image of a whole frog eye that has been labelled with a photoreceptor marker (cyan) and a nuclear marker (orange). The retinal is the striped tissue and the lens is the large round tissue with the orange interior. You can also see the optic nerve at the top middle of the picture (12:00).

Frog eye, frog eye. Can I have a confocal microscope to play on for 12 hrs a day again please? πŸ‘‰πŸ‘ˆπŸ₯Ί 🐸

09.12.2025 19:58 β€” πŸ‘ 49    πŸ” 13    πŸ’¬ 2    πŸ“Œ 0
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Want to image cells protecting the embryo during early development? We're hiring! 1 Postdoc, 1 PhD student, and 1 Research Technician. Come to Barcelona! www.embryobioimaging.com

09.12.2025 17:44 β€” πŸ‘ 5    πŸ” 6    πŸ’¬ 0    πŸ“Œ 2
Brian Cox, Madeline Lancaster and fellow panel member sat on stage with microphones.

Brian Cox, Madeline Lancaster and fellow panel member sat on stage with microphones.

Can we build a human?

Madeline Lancaster joined Brian Cox & a panel of experts for the @crick.ac.uk & BBC Studios podcast A Question of Science, to answer this question.

Find the episode here: www.lnk.to/AQOSBioengin...

#LMBintheNews

@cellbiol-mrclmb.bsky.social @lancasterlab.bsky.social

04.12.2025 14:41 β€” πŸ‘ 7    πŸ” 5    πŸ’¬ 0    πŸ“Œ 0

Reciprocal interactions between EMT and BMP signalling drive collective cell invasion. https://www.biorxiv.org/content/10.64898/2025.12.02.691808v1

04.12.2025 18:30 β€” πŸ‘ 2    πŸ” 1    πŸ’¬ 0    πŸ“Œ 1
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Development's Pathway to Independence Programme Our grants support and encourage the sharing of knowledge throughout the community by facilitating international collaboration, event attendance and the organisation of scientific meetings, conference...

Applications are open for @dev-journal.bsky.social 2026 Pathway to Independence (PI) programme, supporting postdocs applying for group leader positions:

Mentoring
Profile raising
Leadership training
Network building

Spread the word...

www.biologists.com/grants/devel...

03.12.2025 06:56 β€” πŸ‘ 73    πŸ” 83    πŸ’¬ 0    πŸ“Œ 1

@grocottlab is following 20 prominent accounts