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Lars Bock

@larsvbock.bsky.social

Theoretical and computational physicist working on ribosomes and antibiotics - atomistic simulations, statistical physics and ML. Project leader at the MPI for Multidisciplinary Sciences https://t.co/1ecLGaOjXB ๐Ÿšด

1,491 Followers  |  796 Following  |  12 Posts  |  Joined: 19.09.2023  |  1.9085

Latest posts by larsvbock.bsky.social on Bluesky

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๐Ÿ‘‰ Don's miss your chance to join us for the 'Computer Simulation and #Theory of Macromolecules' workshop' in #Hรผnfeld to discuss recent advances in theory and application of# biomolecular #simulations. ๐Ÿ“… Online registration is open until Feb 15, 2026. More info:๐Ÿ”— www.mpinat.mpg.de/workshop/hue...

06.02.2026 14:28 โ€” ๐Ÿ‘ 6    ๐Ÿ” 3    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 0
Job advert for MD related research projects in the department of theoretical and computational biophysics @mpi-nat.bsky.social

Job advert for MD related research projects in the department of theoretical and computational biophysics @mpi-nat.bsky.social

๐Ÿง You are a physicist or chemist who wants to reveal how life works at the molecular level?

๐Ÿค“ You know how to combine computer power and theory to solve biological problems?

โค๏ธ You just love doing science?

๐Ÿ‘‰ Send us your application!
๐Ÿ”— Current job adverts www.mpinat.mpg.de/grubmueller

06.02.2026 15:09 โ€” ๐Ÿ‘ 6    ๐Ÿ” 3    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

๐Ÿ˜ฒ #Deadline is approaching... Don't miss your chance to join the @bioexcelcoe.bsky.social #summer#school on #biomolecular #simulations in #sardinia ๐Ÿ‡ฎ๐Ÿ‡น @gromacs.bsky.social #pmx #hadddock #biobb

28.01.2026 12:11 โ€” ๐Ÿ‘ 3    ๐Ÿ” 2    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
Alex Pretti, wearing a green sweater with his VA badge on.

Alex Pretti, wearing a green sweater with his VA badge on.

This is Alex Pretti.

This morning he was murdered by ICE. Six ICE agents held him down and shot him at point blank range. Alex was a nurse and researcher at the VA.

Our thoughts are with his loved ones and we stand united in action calling for the abolishment of ICE.

#ScientistsAgainstICE

24.01.2026 20:03 โ€” ๐Ÿ‘ 1643    ๐Ÿ” 778    ๐Ÿ’ฌ 27    ๐Ÿ“Œ 35
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Did you miss our 2025 scientific lecture series at the Literaturherbst in Gรถttingen? Stream most German & English talks in full-length on our website๐Ÿ’ป. From baby talk to democracy and the vaccines of the future; there is something interesting for everybody!
www.mpinat.mpg.de/4758909/media

22.01.2026 09:35 โ€” ๐Ÿ‘ 7    ๐Ÿ” 4    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 0
omiddjalili on Instagram: "๐ŸšจDue to the regime cutting off the internet last 5 days messages coming out of Iran have decreased by 99% - this one made it throuโ€ฆ" ๐ŸšจDue to the regime cutting off the internet last 5 days messages coming out of Iran have decreased by 99% - this one made it through. The scale of civilian massacre is far beyond what has been reported. The figure of 12,000 killed is described as โ€˜almost a jokeโ€™ compared to the magnitude of the catastrophe that has taken place.The regime in Iran have carried out widespread and systematic deadly violence. โ€œIt is a massacre beyond human imaginationโ€. There are subtitles so please go to the end. It is still happening. Please share widely.#IranianRevolution2026

Listen to this if you bear. Phone call from #Iran. I will transcript (pardon typos).

"You cannot even imagine. Not even in your imaginations, what is happening in Iran. Thousands and thousands of people have been killed. 1/

www.instagram.com/reel/DTgIUBt...

14.01.2026 19:08 โ€” ๐Ÿ‘ 4    ๐Ÿ” 4    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 0

๐ŸŽ‰ Now also published in @pubs.acs.org #Photonics โฉ pubs.acs.org/doi/10.1021/... #MINFLUX #microscopy #Bayes

13.01.2026 07:44 โ€” ๐Ÿ‘ 2    ๐Ÿ” 1    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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Over 100 hours of Internet and phone blackout, as the regime commits crimes against humanity. The death toll is now in the thousands. If you care *at all* about human rights, do something. Contact your representatives. Demand accountability. History will not forgive you for looking away. #Iran

12.01.2026 22:04 โ€” ๐Ÿ‘ 1    ๐Ÿ” 1    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
Client Challenge

If anyone is interested in making bacterial ribosome-nascent chain complexes and studying them using HDX-MS, we have written up a detailed protocol.
rdcu.be/eYFx4
Characterise the conformational dynamics of the ribosome, nascent polypeptide and bound chaperones, label-free and at peptide-level

12.01.2026 13:29 โ€” ๐Ÿ‘ 9    ๐Ÿ” 8    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 0

Iran has been under communications blackout for over 60 hours now. Several thousand people have been killed (numbers vary by source, I have seen between 2 and 5000 this morning). Iranians abroad don't know if their loved ones are alive or dead, have absolutely no way to communicate 1/

11.01.2026 12:30 โ€” ๐Ÿ‘ 7    ๐Ÿ” 5    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 0

As a reminder, in the 2019 protests, the Iranian regime killed about 1500 people in less than two weeks. They do this under the cover of cutting internet. This time, they have cut off the internet, phone lines, and closed airspace. This is a crisis. Don't look away.

09.01.2026 11:23 โ€” ๐Ÿ‘ 12    ๐Ÿ” 2    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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๐Ÿ“ฃ Talented PhD students wanted: The IMPRS for Genome Science @imprsgs.bsky.social and the DFG Research Training Group GรถnomiX are looking for you!

08.01.2026 08:36 โ€” ๐Ÿ‘ 3    ๐Ÿ” 7    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 0
Alchemistry Workshop in Free Energy Methods for Drug Design - Alchemistry Annual conference on Free Energy Methods in Drug Discovery

Exciting news! We have a new website: omsf.io/alchemistry

Your one-stop shop for everything related to our conference community. ๐ŸŽ‰

BTW, registration is now open, so head over to secure your spot! We'll be sharing updates and details about the event.

Bookmark it as there's plenty more to come!

05.01.2026 20:33 โ€” ๐Ÿ‘ 8    ๐Ÿ” 8    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

๐ŸšจLast chance to apply for two PhD projects in my lab, applying structural biology and single molecule biophysics to investigate gene expression in RNA viruses: www.findaphd.com/phds/?Keywor...

06.01.2026 15:56 โ€” ๐Ÿ‘ 9    ๐Ÿ” 10    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

๐Ÿ‘‰Applications will be reviewed on a rolling basis until the #postodc or #phd #position is filled. ๐Ÿ“ฉ Send us your message to explain why you are a great candidate to join the group "Computational Biomolecular Dynamics" of Bert de Groot @mpi-nat.bsky.social ๐Ÿ”— www.mpinat.mpg.de/degroot #compbiophys

14.11.2025 13:40 โ€” ๐Ÿ‘ 4    ๐Ÿ” 4    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 1

anyone got any advice on the following situation? I wrote and did a big chunk of the admin for a large MRC grant which also also awarded. I am named in the Staff breakdown on the grant as "researcher co-lead" with 100%FTE, and I am mentioned by name as "postdoctoral researcher Maria Niedernhuber"

09.12.2025 13:37 โ€” ๐Ÿ‘ 8    ๐Ÿ” 11    ๐Ÿ’ฌ 10    ๐Ÿ“Œ 1

Welcome to bluesky, Mika!

07.12.2025 10:19 โ€” ๐Ÿ‘ 1    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
Independent Research Group Leaders (f/m/d) SCALE / FIAS

The Frankfurt Institute for Advanced Studies (FIAS) and the newly funded Cluster of Excellence SCALE are seeking several Independent Research Group Leaders to drive theoretical and computational research in molecular and cellular life science.

fias.institute/de/das-fias/...

05.12.2025 17:30 โ€” ๐Ÿ‘ 11    ๐Ÿ” 10    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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๐Ÿ“œ New preprint! We developed PoGรถ, an algorithm to optimize the essential dynamics of GรถMartini proteins based on all-atom simulations: www.biorxiv.org/content/10.1...

27.10.2025 07:54 โ€” ๐Ÿ‘ 33    ๐Ÿ” 12    ๐Ÿ’ฌ 2    ๐Ÿ“Œ 3

Awesome to see this epic piece of work, led by @cecclementi.bsky.social, finally appear in @natchem.nature.com.

The development of a general coarse-grained protein forcefield to describe folding, binding and conformation changes without solvent and all-atom, has been long anticipated!

18.07.2025 11:25 โ€” ๐Ÿ‘ 31    ๐Ÿ” 6    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 0
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Dynamics and Energetics of Ribosomal Translation

๐Ÿฆ For the early birds and #ribosome #MD and #ML enthusiasts #EBSA2025: Don't miss ๐Ÿ“Œ Lars' @larsvbock.bsky.social oral presentation (O-16.1) tomorrow at 8:30 during session 16 in hall 1: "Combining #Simulations and Machine Learning with Experiments to Explore Ribosomal #Translation" ๐Ÿ”— t1p.de/ccmwk

03.07.2025 13:04 โ€” ๐Ÿ‘ 7    ๐Ÿ” 2    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

One day remaining before this closes!
bsky.app/profile/benj...

21.06.2025 04:45 โ€” ๐Ÿ‘ 6    ๐Ÿ” 1    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

๐Ÿ†•๐Ÿ“ฃ Job alert: Our department @compbiophys.bsky.social is looking for a PhD student or Postdoc specializing in theory and methods for non-equilibrium theory and atomistic simulations of complex biomolecules.
More information here: โฌ‡๏ธ

07.04.2025 11:55 โ€” ๐Ÿ‘ 4    ๐Ÿ” 1    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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๐Ÿ’ญ Would you like to contribute to projects in the field of "Theory and Methods for Non-equilibrium #Theory and Atomistic Simulations of Complex# Biomolecules"? Join our department as #PhD student or #Postdoc at @mpi-nat.bsky.social in ๐Ÿ‡ฉ๐Ÿ‡ช ๐Ÿ”— Here are more details www.mpinat.mpg.de/4965656/10-2... #job

01.04.2025 13:11 โ€” ๐Ÿ‘ 6    ๐Ÿ” 3    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 2
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Structural switching dynamically controls the doubly pseudoknotted Rous sarcoma virusโ€“programmed ribosomal frameshifting element | PNAS A hallmark of retrovirus replication is the translation of two different polyproteins from one RNA through programmed –1 frameshifting. This is a m...

Excited to share my latest research. In this paper in PNAS, I use #cryoEM and #crystallography to solve multiple new structures of a viral RNA motif that controls frameshifting.

#virus #retrovirus #structuralbiology #science #biochemistry

www.pnas.org/doi/10.1073/...

02.04.2025 16:36 โ€” ๐Ÿ‘ 18    ๐Ÿ” 6    ๐Ÿ’ฌ 2    ๐Ÿ“Œ 0
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๐Ÿง Are you a computational physicist and expert in probability theory? ๐Ÿ‘‰ Contribute to our project "Theory and Algorithms for Structure Determination from Single Molecule X-Ray Scattering Images" as PhD student or Postdoc! ๐Ÿ”— Check our job advert for more details www.mpinat.mpg.de/4988122/09-2...

01.04.2025 13:01 โ€” ๐Ÿ‘ 11    ๐Ÿ” 9    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 2

Gemma Solomon and I are looking for a postdoc to work across the two groups on modelling biological systems with a view to applications for quantum computing

More details about the project including how to apply in the link below. Deadline April 9 2025

candidate.hr-manager.net/ApplicationI...

22.03.2025 19:18 โ€” ๐Ÿ‘ 42    ๐Ÿ” 29    ๐Ÿ’ฌ 3    ๐Ÿ“Œ 1
"A screenshot of an NBC News article headline. The headline reads: 'Texas bill would make identifying as transgender a felony punishable by jail.' Below the headline, a subtext states: 'The bill, while unlikely to pass, highlights the increasing extremism of legislation targeting trans people, especially in Texas, in recent years.' The NBC News logo is visible at the top, along with a navigation bar that includes a 'WATCH' button and a user profile icon."

"A screenshot of an NBC News article headline. The headline reads: 'Texas bill would make identifying as transgender a felony punishable by jail.' Below the headline, a subtext states: 'The bill, while unlikely to pass, highlights the increasing extremism of legislation targeting trans people, especially in Texas, in recent years.' The NBC News logo is visible at the top, along with a navigation bar that includes a 'WATCH' button and a user profile icon."

I need y'all to sit with this headline and understand what is being done to our community. They're trying to criminalize our very existence.

This is a campaign of eradication.

www.nbcnews.com/nbc-out/rcna...

10.03.2025 19:32 โ€” ๐Ÿ‘ 25496    ๐Ÿ” 11180    ๐Ÿ’ฌ 675    ๐Ÿ“Œ 967
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There was a lot of #AcademicFreedom, good scholarship, and independent thought in German universities before Hitler. After Hitler had risen to power, many academics fled the country. Some resisted the Nazi regime and were persecuted. Most adapted to a new situation. Here are some examples. 1/n

20.01.2025 05:26 โ€” ๐Ÿ‘ 1737    ๐Ÿ” 898    ๐Ÿ’ฌ 64    ๐Ÿ“Œ 143

@larsvbock is following 20 prominent accounts