Simon Cleary

Useful article addressing an often-overlooked way in which research impacts the environment:

Oral Nalbuphine in Idiopathic Pulmonary Fibrosis–Associated Cough This randomized clinical trial examines the safety and efficacy of oral nalbuphine in patients with chronic cough caused by idiopathic pulmonary fibrosis.

Good news!! Oral Nalbuphine reduces cough count baseline by ~50 % in Idiopathic Pulmonary Fibrosis–Associated Cough jamanetwork.com/journals/jam...

Nice evidence for a role for the ectonucleotidase CD39 in limiting pulmonary thromboembolism in sickle cell disease with striking footage of this process!

"Does this handle survival plots too?" asked @load-dependent.bsky.social

Yes it does! See below for RECOVERY.

Only catch is it doesn't like the dotted lines that appear in some survival plots (because the PDF geometry treats this as lots of little separate lines rather than one single entry).

Thanks, odd decisions being made at a company with a focus on preventing plagiarism.

Can you link to more information on this?

Tumor-draining Lymph nodes - Online event next week!
follow the link to register

On January 13 from 11:30 – 1:00 pm ET, @thelundlab.bsky.social , Dr. Ivan Maillard, @actonlab.bsky.social , & Dr. Burkhard Ludewig will discuss lymph node remodeling in cancer:

events.cancer.gov/dcb/tdln #TLDNForums

Absolutely delighted that our latest paper is out today @natimmunol.nature.com. It has taken five years to uncover a role for cross-presentation in shaping the immune visibility of tumour antigens. A labour of love led by @drjonlim.bsky.social and Oliver Schulz. Great start of 2026!

This is cool stuff - imaging covalent drug biodistribution using tissue clearing methods

I am reminded of @charlottesummers.bsky.social presenting images taken on gamma scanners made from pre-war steel, the only steel free from contamination with fallout from nuclear weapons tests...

Please check out our job post @biologists.bsky.social!

We are recruiting a Postdoc Scientist to develop cutting-edge tools and techniques for bioengineering human lymphatic networks, as part of an interdisciplinary collaboration with the group of Prof Dame Molly Stevens!

bit.ly/3La9idq

Enjoyed learning about the importance of Batf3 for IL-17-producing γδ T cell responses that protect neonates during influenza infection! Congrats Pedro and colleagues!

Are you an emerging clinical academic leader in respiratory medicine?
Come and join @vpd-hlri.bsky.social and @royalpapworth.bsky.social and build your career!
Get in touch if you’d like to discuss.

www.cam.ac.uk/jobs/assista...

Love these 3D renderings of the extracellular matrix cages surrounding megakaryocytes!

bsky.app/profile/wcla...

Fun revisiting this study and looking at the eLife peer review system for this postLight:

Heading to BSI congress? Plan on attending this all-star session, Thursday at 11AM, chaired by @doreenlau.bsky.social and me!

Doctoral INPhINIT fellowships - Incoming Call 2026 We grant 30 fellowships for researchers of any nationality who wish to pursue a doctorate in a STEM discipline at research centres of excellence in Spain or Portugal.

Outstanding PhD fellowship call OPEN for excellent students.

lacaixafoundation.org/en/doctoral-...

This is for students incoming from outside Spain. And it is VERY well supported (ie at European levels).

If you’re interested in doing a PhD in our lab @irbbarcelona.org, reach out!!!!

Looking forward to chairing a session with @doreenlau.bsky.social at the British Society for Immunology Congress next week!

Great line-up of speakers. Send an email if you would like to meet at or around the conference.

Reader in/Professor of Immunobiology | King's College London

We are recruiting a Reader/Professor of Immunobiology at @kingslsm.bsky.social . This is a unique opportunity to shape basic immunology at @kingscollegelondon.bsky.social . Please RP.
www.kcl.ac.uk/jobs/131447-...

Getting distracted like @bryanwelm.bsky.social states above - the slide drawn by the Family Guy animators has incompatible gears that would either never or always grind and are not in contact with each other. Weak, distracting messaging.

'B' frequently happens and would grind my gears if it weren't so funny.

Great to hear good news on reproducibility!

Nice! Interesting that the screenshot seems to reference the 'arsenic life' paper but not mentioned in the blog post, what's the story behind that?

DNGR-1 signalling limits dendritic cell activation for optimal antigen cross-presentation | The EMBO Journal imageimageDNGR-1 (CLEC9A) is a C-type lectin receptor of type-1 conventional dendritic cells (cDC1s) with an important role in cross-presentation of dead cell antigens. This study explores how it equips cDC1s with the ability to cross-present such ...

Delighted that this study is finally out @embojournal.org. A detailed analysis of how DNGR-1/CLEC9A signals to promote cross-presentation of dead cell-associated antigens yet does not activate dendritic cells.
www.embopress.org/doi/full/10....

Assaying lung samples using spectral flow cytometry? Check out AutoSpectral:

Membrane Perturbations and Assay Interferences by Ivermectin Explain Its In Vitro SARS-CoV-2 Antiviral Activities and Lack of Translatability The antiparasitic drug ivermectin was proposed as a repurposed drug for the treatment of SARS-CoV-2 infection based on in vitro studies, but proved ineffective in high-quality clinical trials. When ex...

Some good weekend reading. If you thought we’d put the final nails in the coffin of ivermectin as a Covid treatment, you’d be right. But this Perspective goes the extra mile to put the coffin in a lead-lined box and sink it to the bottom of the ocean. 🧵

It’s official! 🎉
Our latest paper on the role of the extracellular matrix (ECM) in megakaryopoiesis is out in @elife.bsky.social !
🔗 elifesciences.org/articles/104...
I’m thrilled to share this story with you in a short thread 👇

Bioimage Analysis Specialist | King's College London

BioImage analysis friends - King's are recruiting for a full-time, permanent facility position! Come and work with fun microscopes and fun people (and me!) - please share! www.kcl.ac.uk/jobs/126345-...

Image of a fluorescently labeled adult mouse kidney showing AQP2 staining of collecting ducts and connecting segment in green and alpha SMA staining of the arterial tree in magenta. The collecting ducts look like squiggly branches.

For this #FluorescenceFriday, a gorgeous image of an adult mouse kidney labeled with AQP2 and alpha SMA antibodies. AQP2 (green) marks the collecting duct and distal connecting segment while SMA marks the arterial tree. Courtesy of talented postdoc Sarah McLarnon.

Enhancing pulmonary vascular function to heal injured lungs - MRC DTP To develop improved treatments for inflammatory diseases, we need a better understanding of how pro-inflammatory leukocyte responses resolve. During inflammatory resolution, some recruited leukocytes ...

PhD scholarships available incl. a project with me & Alex Ivetic at King's College London - great programme, facilities, city, colleagues!

Please forward to any suitable undergraduates/MSc students/research assistants.

Info: kcl-mrcdtp.com/project/enha...