Chang Jiang

😆

29.01.2026 17:50 — 👍 0    🔁 0    💬 0    📌 0

Grant rejections. Pressure from every direction.
Then an undergraduate leading a project tells me after a 1:1,
“Joining your lab was the best decision I made.”
Tears came out.
This is why I do it.

29.01.2026 17:32 — 👍 0    🔁 0    💬 0    📌 0

Induced ubiquitination bypasses canonical ERAD to drive ER protein degradation Heterobifunctional proteolysis-targeting chimeras (PROTACs) have emerged as a powerful strategy to degrade disease-relevant proteins, enabling targeting of previously "undruggable" proteins. Current d...

New preprint out! We show that PROTAC-induced ubiquitination can bypass canonical ERAD to degrade ER membrane proteins. Wonderful collaboration w/ @dannomura.bsky.social and huge credit to grad student superstar Sydney Tomlinson!
www.biorxiv.org/content/10.1...

01.12.2025 17:14 — 👍 41    🔁 15    💬 0    📌 0

Tumor nutrient stress gives rise to a drug tolerant cell state in pancreatic cancer Cytotoxic chemotherapy remains the standard-of-care treatment for patients with pancreatic ductal adenocarcinoma (PDAC). However, chemotherapy only has modest effects at improving patient survival due...

Super excited to share our new preprint from @cssheehan.bsky.social on how the tumor microenvironment causes drug resistance in pancreatic cancer: www.biorxiv.org/content/10.1...

09.09.2025 21:38 — 👍 32    🔁 9    💬 1    📌 0

New PI life: competing with the “big labs” for rotation students feels like bringing a salad to a pizza party. 🍕🥗 No takers this round, but we’ll keep cooking 💪— the right students will come🫵

10.09.2025 00:30 — 👍 2    🔁 0    💬 0    📌 0

Congratulations!🎉🍾🎈

23.07.2025 02:16 — 👍 0    🔁 0    💬 0    📌 0

The Jiang Lab are having a great time at #ASBMB25 in Chicago!

16.04.2025 01:56 — 👍 6    🔁 1    💬 0    📌 0

The Jiang lab@Moffitt is attending @ASBMB! If you are interested in redox biology and cancer metabolism, check out our posters as listed below on Monday, April 14th, 2025! See you in Chicago! We are hiring now!

12.04.2025 18:55 — 👍 8    🔁 1    💬 0    📌 0