Our new preprint reveals that 🪰's Cnn and 🪱's SPD-5 both form condensates in vitro, but assemble via divergent mechanisms in vivo. We show how phosphorylation unlocks Cnn’s autoinhibited scaffold and identify conserved features in 🚶♂️'s CDK5RAP2.
05.10.2025 04:19 — 👍 6 🔁 3 💬 0 📌 0
Centrioles generate two scaffolds with distinct biophysical properties to build mitotic centrosomes
Spd-2 organizes the assembly of two distinct centriole-scaffolds to build mitotic centrosomes in Drosophila.
Exciting news! Our latest paper reveals that Spd-2 (CEP192) recruits Polo & Aurora A to build two scaffolds—Polo-dependent Cnn (for strength) & Aurora A–dependent TACC (for protein concentration)—crucial for centrosome assembly in Drosophila. #CellBiology #Centrosome www.science.org/doi/10.1126/...
08.02.2025 05:04 — 👍 15 🔁 8 💬 2 📌 0
EMBO and HFSP postdoctoral fellow in the Paul Nurse Lab @crick.ac.uk. Biophysicist studying biology from single molecules to the systems level. Alumnus of @reyes-lab.bsky.social @mcgill.ca 🇨🇦
Marine plankton, home educator, biology undergrad, autistic, non binary. Norfolk UK. Runs The Plankton Project
linktr.ee/elizabethbeston
Associate Prof. at WashU School of Medicine; biophysics/biochem/evolution of intrinsically disordered proteins. How does nature encode function without a stable structure? We work in vivo / in vitro / in silico. He/him.
https://www.holehouselab.com/
Group Leader @MRC_LMB /Structural Biologist/Biochemist. Amateur baker in free time #RNAworld #spliceosome #telomerase #telomeres #cryoEM #Xraycrystallography
Not-for-profit publisher of Development, Journal of Cell Science, Journal of Experimental Biology, Disease Models & Mechanisms and Biology Open. Host of community sites the Node, preLights and FocalPlane. Supporting biologists and inspiring biology.
Developing data intensive computational methods • PI @ Seoul National University 🇰🇷 • #FirstGen • he/him • Hauptschüler
Scientist by day (drummondlab.org), artist by night (dadrummond.art). Sculpture, drawings, and other works. Obsessed with the details of the natural world. Lab posts at @drummondlab.bsky.social 🧪
professor at UCSF, engineer turned cell biologist, wants to know how cells solve geometry problems
Professor at UCSF. Physical cell biologist exploring life. Cell size, shape and division. Cytoplasm. Fungi. Views are my own. 🌈
Science and fun from the lab of Tony Hyman at the MPI-CBG @mpicbg.bsky.social. Tweets by Hymanlab members.
https://hymanlab.org/
Non-profit research and educational institution at the forefront of molecular biology, cancer, neuroscience, plant biology, and genetics.
https://www.cshl.edu/
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Research, news, and commentary from Nature, the international science journal. For daily science news, get Nature Briefing: https://go.nature.com/get-Nature-Briefing
Cell Press partners with scientists across all disciplines to publish and share work that will inspire future directions in research. #ScienceThatInspires
The European Molecular Biology Laboratory drives visionary basic research and technology development in the life sciences. www.embl.org
🌐 Internationally renowned #Research Center
🏥 State-of-the-art Hospital Group
🇨🇵 France's leading #cancer center
curie.fr
Hamamatsu Photonics is a leading manufacturer of devices for visible, infrared, ultraviolet, and x-rays. We are dedicated to enhancing life through light-based technologies.
https://www.hamamatsu.com/
Bioengineering, Biophysics, Computational Biology and Molecular and Cell Biology. Account run by students/post-docs.
Lab website: https://fletchlab.berkeley.edu/
Cutting-edge research, news, commentary, and visuals from the Science family of journals. https://www.science.org
