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Isaac Wong

@isaacsiuwong.bsky.social

Cell Biologist

109 Followers  |  112 Following  |  1 Posts  |  Joined: 02.11.2024  |  1.3802

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Centrioles generate two scaffolds with distinct biophysical properties to build mitotic centrosomes Spd-2 organizes the assembly of two distinct centriole-scaffolds to build mitotic centrosomes in Drosophila.

Exciting news! Our latest paper reveals that Spd-2 (CEP192) recruits Polo & Aurora A to build two scaffolds—Polo-dependent Cnn (for strength) & Aurora A–dependent TACC (for protein concentration)—crucial for centrosome assembly in Drosophila. #CellBiology #Centrosome www.science.org/doi/10.1126/...

08.02.2025 05:04 — 👍 15    🔁 8    💬 2    📌 0

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