CGM at MGH

@cgm-mgh.bsky.social faculty Chris Anderson and team found polygenic risk scores, combined w/ clinical predictors, can help identify patients most likely to develop atrial fibrillation after stroke loom.ly/QQQFp8s

05.02.2025 14:02 — 👍 0    🔁 0    💬 0    📌 0

🚨🚨🚨 In collaboration with @pnatarajanmd.bsky.social we are excited to launch gVasc, a new biobank focused on the genetics of spontaneous coronary artery dissection (SCAD)! with a participant-facing enrollment portal,
👉 gvascstudy.org 👈

09.01.2025 00:02 — 👍 41    🔁 15    💬 1    📌 0

A special congratulations to Konrad Karczewski, Siwei Chen, @ksamocha.bsky.social and Mike Guo for all their hard work on these publications. Read more about this work at www.nature.com/articles/d41... (2/2)

06.12.2023 18:21 — 👍 3    🔁 1    💬 0    📌 0

🚨New paper out in Nature Mental Health from my work with @erindunnscd.bsky.social at #MassGeneral! We found that childhood adversity leads to #epigenetic changes that can increase OR reduce risk for depression. Let me explain... 🧵(1/6)

Read the paper here: www.nature.com/articles/s44...

02.12.2024 20:11 — 👍 28    🔁 8    💬 2    📌 4

Resolution of ring chromosomes, Robertsonian translocations, and complex structural variants from long-read sequencing and telomere-to-telomere assembly Delineation of structural variants (SVs) at sequence resolution in highly repetitive genomic regions has long been intractable. The sequence propertie…

Researchers @TalkowskiLab used long-read sequencing and the T2T reference to characterize previously intractable genome rearrangements (e.g. ring chroms, Robertsonian translocations), shining light on their formation and consequences. @ajhgnews.bsky.social www.sciencedirect.com/science/arti...

29.01.2025 17:10 — 👍 1    🔁 1    💬 0    📌 0