Jonathan Wirsich

When @laurapritschet.bsky.social & Pavel Shapturenka set out to build the 28&Me + 28&He datasets, I don't think any of us could've predicted the spectacularly creative ways the datasets would be used years later. That's the power of open science. 👇🏼

The Cambridge Handbook of Human Affective Neuroscience Cambridge Core - Cognition - The Cambridge Handbook of Human Affective Neuroscience

#emotion
Armony, J., & Vuilleumier, P. (2025). The Cambridge handbook of human affective neuroscience (2nd ed.). Cambridge University Press. doi.org/10.1017/9781...

New layer-fMRI preprint using simultaneous layer-fMRI with EEG at 7T. Establishing an acquisition and analysis setup to capture layer-fMRI correlates of spontaneous alpha power variations.
By Marsh et al.
doi.org/10.1101/2025...

Normative framework of bigger tech

(aka, me trolling the tech audience)

Ever wondered if your interesting brain-behavior correlation was over- or under-estimated due to head motion, but were afraid to ask? We’ve created a motion impact score for detecting spurious brain-behavior associations, now available in Nature Communications!
doi.org/10.1038/s414...

Disentangling metabolic and neurovascular timescales supporting cognitive processes | PNAS The balance between neural excitation and inhibition (EIB), governed by glutamatergic and GABAergic neurotransmission, is an essential mechanism su...

Excited to share such a career milestone 🌟 Our new @pnas.org paper shows how E–I balance drives dynamic brain adaptation.

Thanks to @jorgejovicich.bsky.social, @dimitrivdv.bsky.social, @asiaferrari.bsky.social, @bcassone.bsky.social & amazing co-authors 🙏
🔗 www.pnas.org/doi/10.1073/...

good idea! any open datasets you could recommend from your group as a starting point?

This was my first paper with the new @elife.bsky.social model. Have to say, while I don't agree with all the reviewers' comments the new process is awesome. We can directly reply to their concerns and it'll be obvious what changed between revisions when we upload the revised version :) 4/4

We are hiring !

👩🏼‍🎓👨‍🎓🧑🏼‍🎓👨🏿‍🎓👩🏿‍🎓👩‍🎓

I am looking for a motivated person interested in a PhD in basic neuroscience, for a project at the edge between epilepsy and sleep.

If you are interested, check the job announcement:
jobs.unige.ch/www/wd_porta...

Maybe. But what would it mean anyways 😉:
bsky.app/profile/hyru...
2025.ccneuro.org/poster/?id=n...

Launched in 2023, Imaging Neuroscience is now firmly established, with full indexing (PubMed, etc.) and 700 papers to date.

We're very happy to announce that we are able to reduce the APC to $1400.

Huge thanks to all authors, reviewers, editorial team+board, and MIT Press.

The potential of laminar functional MRI in refining the understanding of epilepsy in humans Aitken et al. highlight laminar fMRI as a tool to connect the neural effects of anti-seizure medications with the microcircuits that generate seizures in e

Our review discussing the potential use of laminar fMRI for probing the role of cortical layers in epileptic seizure propagation and spread as well as it possible future clinical applications out in Brain (well as accepted manuscript!)

academic.oup.com/brain/advanc...

Happy to see this out: our new preprint shows that laminar GE-BOLD fMRI decoding isn’t immune to vascular draining biases. Simulations reveal false positives due to multivariate signal spread across layers, but oversampling + deconvolution can (sometimes) improve specificity.

New paper🥳

🧠 In TLE, brain changes go beyond the temporal lobe & beyond normal aging.

Our ENIGMA study (769 patients, 18 sites) found widespread gray & white matter decline, especially after 55. By Judy Chen and a terrific intl' team

Time for earlier diagnosis & deeper research
bit.ly/3HRYeQt

Data available via @ebrains.bsky.social : doi.org/10.25493/B3B... Also big thanks to their contribution :)

High-Density EEG Source Localisation of averaged interictal epileptic Discharges validated by surgical Outcome - Scientific Data Scientific Data - High-Density EEG Source Localisation of averaged interictal epileptic Discharges validated by surgical Outcome

Interested in Epileptic Discharges? In need of a data set to validate your source reconstruction models based on clinical outcome? Check out our newest: www.nature.com/articles/s41...
Big thanks to B. Vorderwülbecke, S. Vuillémoz et al. ! - @seeber.bsky.social @cibm.bsky.social

Poster titled "Neuromod: The Courtois Project on Neuronal Modelling" with logos from Université de Montréal and the Centre de recherche de l'Institut universitaire de gériatrie de Montréal. Large bold text reads: 6 BRAINS – 987H-fMRI – 18 TASKS Followed by the subtitle: Naturalistic & Controlled – Multimodal / Perception + Action Each letter in "18 TASKS" contains thumbnails from various visual tasks. The central table summarizes 32 datasets grouped by primary domain (Vision, Audition, Language, Memory, Action, Other). For each dataset, the table indicates which stimulus modalities were used (Vision, Speech, Audio, Motion), what responses were collected (Physiology, Eye tracking, Explanations, Actions), and how many sessions and subjects were scanned. The overall visual style is playful and bold, with rainbow colors for modality types and rich iconography indicating data types.

In 2019, the CNeuroMod team and 6 participants began a massive data collection journey: twice-weekly MRI scans for most of 5 years. Data collection is now complete! 1/🧵

5. It has been centuries since any one human could know everything that is known; understand everything that is understood.

This is a remarkable power of science. We delegate trust and authority to experts as internally established in ways that are remarkably resilient to mistakes and malfeasance.

Thanks to all (co)authors & reviewers for their contribution to this study on #layer specific changes in #sensory #cortex across the #lifespan in #humans & #mice now out in @natneuro.nature.com Here is a short summary of our findings 1/6

The names of the speakers in alphabetical order: Melanie Boly Ray Dolan Davide Folloni Laura Gwilliams Charles Hillman Hilleke Hulshoff Pol Jean-Rémi King Daniel Margulies Lucia Melloni

Get ready for a milestone! The 20th Alpine Brain Imaging Meeting (ABIM) will take place January 11-15, 2026. We have a fantastic lineup of speakers and many special events planned, from our ski races to scientific debates on the past (& next!) 20 years of neuroimaging research. #ABIM2026

A do-or-die moment for the scientific enterprise Reflecting on our paper “The entities enabling scientific fraud at scale are large, resilient, and growing rapidly”

Today, our article "The entities enabling scientific fraud at scale are large, resilient, and growing rapidly" is finally published in PNAS. I hope that it proves to be a wake-up-call for the whole scientific community.

reeserichardson.blog/2025/08/04/a...

New publishing models will only work if authors embrace them Complaints about the broken academic publishing system have been around for years and are getting louder. A common theme is that with the r...

Here's a quick blogpost about alternative publishing models. You can bring a horse to water, and indeed wave the bucket temptingly under its nose, but it is likely to gallop off elsewhere. deevybee.blogspot.com/2025/07/new-...
@ec.europa.eu @wellcometrust.bsky.social

No statement on the code availability... sharing the statistical maps of the group analysis is not restricted by privacy laws in Europe? It's the year 2025, this should be enforced more consistently by the editors

New paper in Imaging Neuroscience by Alice Giubergia, Denis Peruzzo, et al:

Multi-echo versus single-echo EPI sequences for task-fMRI: A comparative study

doi.org/10.1162/IMAG...

Brain Surfaces of 70 primate species

1
To predict the behaviour of a primate, would you rather base your guess on a closely related species or one with a similar brain shape? We looked at brains & behaviours of 70 species, you’ll be surprised!

🧵Thread on our new preprint with @r3rt0.bsky.social , doi.org/10.1101/2025...

In February 2024, I wrote Scientific Reports about a published meta-analysis claiming that mindfulness interventions affect neural plasticity, 'cementing the neuropsychological basis of mindfulness-based interventions'.

The paper was retracted yesterday—here a little summary of the process.🧵

New layer-fMRI preprint by Clauner et al.

Interleaved EEG and layer-fMRI is used to investigate feature-specific and unspecific correlates of alpha and gamma oscillations in superficial and deeper layers.

doi.org/10.1101/2024...

img/hdr analyze format ;)

I'm so happy someone finally compared fMRI to EEG correlations across datasets and fields strengths!
The study confirms that alpha power correlates negatively with the visual and dorsal attention networks and positively with the default mode network.