Frankly, I’d like for MBI to let ME know.

05.08.2025 19:13 — 👍 2    🔁 0    💬 0    📌 0

Glad to see this out in the world. We observe remarkable rescue in an HD mouse using an ASO targeting intron-1 of Huntingtin, rather than downstream. The intron-1 targeting ASO essentially completely eliminates aggregates, whereas the more distal ASO does nothing: www.biorxiv.org/content/10.1...

31.07.2025 17:57 — 👍 3    🔁 2    💬 1    📌 0

UW Human Resources University of Washington Human Resources

Scientists, especially Seattle ones! One of my research scientists is heading to her PhD and we're looking to fill her spot, if not replace her. If you know someone looking to do cool and impactful translational research give them this:

uwhires.admin.washington.edu/ENG/Candidat...

21.07.2025 18:56 — 👍 4    🔁 6    💬 1    📌 0

imagine cradling your newborn in your arms, looking into his eyes for the first time, and naming him Jeff

10.07.2025 13:41 — 👍 3044    🔁 157    💬 271    📌 42

Close To Jeff Sort of a perk, right? Okay, sure, you and Jeff aren’t that close these days, but in theory it might be nice to see him more often. He could, like, come over for beers in the garage sometimes. Reference #34675

12.05.2025 22:00 — 👍 1012    🔁 46    💬 20    📌 12

Scientist Can’t Forgive Himself For Pressuring Mouse To Try Drugs For The First Time ATLANTA—Expressing his deep regret for the effects of his past actions, scientist Gabriel Foster admitted to reporters Thursday that he can’t forgive himself for pressuring a young lab mouse to try dr...

Tough to choose, but I’ll go with:
theonion.com/scientist-ca...

01.04.2025 14:22 — 👍 49    🔁 7    💬 1    📌 0

NIH cuts are hitting young scientists the hardest. By David Baker. timmermanreport.com/2025/03/davi...

12.03.2025 12:58 — 👍 22    🔁 22    💬 0    📌 1

Not the neuroplasticity I was hoping for.

04.03.2025 01:48 — 👍 2    🔁 0    💬 0    📌 0

I love this.

02.03.2025 02:54 — 👍 0    🔁 0    💬 0    📌 0

A dark-brown mushroom that’s huge is growing out of some ferny woods.

Some stripey mushrooms growing out of a downed tree. Some lush green moss is also visible.

Shot from below of a mushroom growing out of a tree, its gills are visible through the mushroom’s body.

Some more stripey shrooms.

Went for a lovely, dark, wet walk in the woods with my kid today. Found lots of mushrooms, had a great time. Feel free to chime in if you know what they are, because I’m hopeless.
#pnw #mushrooms

17.02.2025 23:46 — 👍 6    🔁 0    💬 0    📌 0

Upon leaving Spotify Premium, you’re given a playlist with song titles: If, You, Leave Us, Now, You’ll, Take Away, The, Biggest, Part of Us.

Touché, Spotify

10.02.2025 04:31 — 👍 2    🔁 0    💬 0    📌 0

I am one of these NSF postdocs. NSF has frozen everyone’s access to their salaries and research stipends (that were already awarded) with no information about when they might be expected to be unfrozen. It still appears like we are expected to continue doing our work though.

31.01.2025 00:43 — 👍 1388    🔁 596    💬 37    📌 18

You may ask yourself, how do I work this?
You may ask yourself, where is that large automobile?
You may tell yourself, this is not my beautiful house!
You may tell yourself, this is not my beautiful data.

29.01.2025 16:47 — 👍 0    🔁 0    💬 0    📌 0

As the insanity creeps up in advance of this RO1 submission, we’ve realized that you can replace “water” with “data” in One in a Lifetime:

Letting the days go by, let the data hold me down
Letting the days go by, data flowing underground

29.01.2025 16:44 — 👍 0    🔁 0    💬 1    📌 0

FWIW, that coronal mouse brain image I use as a banner was taken on an NSF-funded confocal microscope at WWU. I used it to train well over a dozen undergraduate researchers in fluorescent mircroscopy-based coursework, in addition to using it for my own work. 🧪🔬🥼👩‍🔬🧬

29.01.2025 15:15 — 👍 1    🔁 0    💬 0    📌 0

I’m counting on you to get me through this, little buddy.

27.01.2025 03:24 — 👍 0    🔁 0    💬 0    📌 0

omg it worked. Discover feed is just talking about R packages now.

27.01.2025 01:48 — 👍 0    🔁 0    💬 0    📌 0

Learning about the Bsky feed:
One l¡nux post, and my discover feed is all about l¡nux.
One w@terfall pic: feed’s now just w@terfalls 🤣.

Let’s see if this moves the needle: molecular genetics, dataviz, neurodegeneration, neurogenetics, bioinformatics.

26.01.2025 15:57 — 👍 1    🔁 0    💬 1    📌 0

A photo of a waterfall running through moss-covered rocks, surrounded by trees.

A lovely waterfall from my ride today.

26.01.2025 01:35 — 👍 121    🔁 8    💬 1    📌 0

Thanks Gerr!

09.01.2025 02:59 — 👍 1    🔁 0    💬 0    📌 0

Dell re-names the XPS lineup on the same day I convert my ancient XPS 13 to Linux full-time. Coincidence?

07.01.2025 20:12 — 👍 0    🔁 0    💬 0    📌 0

Promoting this freshly revised HTT-chromatin interaction preprint that I've been working on with @jcarroll42.bsky.social as my first skeet. www.biorxiv.org/content/10.1...

07.01.2025 19:25 — 👍 1    🔁 0    💬 0    📌 1

No exceptions for involving JPH3?

21.12.2024 15:36 — 👍 1    🔁 0    💬 1    📌 0