New study reveals how M. tuberculosis PdtaS, a constitutively active kinase, senses both copper and nitric oxide by inhibiting dimerization, not binding.
A fresh twist on two-component signaling!
βοΈ @michaelglickman.bsky.social and coll. πππ
π shorturl.at/DiWXp
#Tuberculosis #MicroSky
20.05.2025 01:38 β π 18 π 7 π¬ 0 π 1
Join us in Tubingen as a Junior Research Group Leader if you do research on #ESKAPE pathogens and infections and are interested in the highly cooperative environment of @dzif.bsky.social⬠and @cmfi.bsky.social ! Please send your application or forward to colleagues!
uni-tuebingen.de/universitaet...
19.05.2025 09:18 β π 35 π 64 π¬ 1 π 2
Happy World tuberculosis day! Thanks to amazing collaborations between medicinal chemistry and microbiology at @pasteurlille.bsky.social we do our best to develop novel anti-tuberculosis therapies such as through our collaborative effort on the novel antibiotic class of TricyclicSpirolactams .
24.03.2025 14:54 β π 11 π 1 π¬ 1 π 0
Funding cuts impact access to tuberculosis (TB) services for millions.
Early reports to WHO from the 30 highest #tuberculosis (TB)-burden countries confirm that funding cuts from foreign aid, particularly from USAID, are already dismantling essential TB services.
Without urgent action, these setbacks will reverse decades of progress to #EndTB π bit.ly/4kvsu2i
06.03.2025 08:58 β π 654 π 287 π¬ 16 π 16
Science, research & public health face unprecedented attacks in the U.S.
We stand with our American colleagues & support the Stand Up for Science call.
Join the global march tomorrow, incl. in Paris! π§ͺβ
π March 7, 13:30 β Place Jussieu
π More info: standupforscience.fr
#StandUpForScience
06.03.2025 14:24 β π 264 π 82 π¬ 3 π 5
Research consortium developing new treatments for TB
European Regimen Accelerator for Tuberculosis
Grant Agreement no. 853989 β ERA4TB
era4tb.org
Relaying microbiology news, articles and comments relevant to aspects on bacteria, fungi, viruses and other microbes / microorganisms. Microbes are πͺ
Mycobacteriologist and Postdoctoral Fellow in the York Bioenergetics Lab, University Of York (@jnb-lab.bsky.social).
Formerly: @pembroke1347.bsky.social & @mrclmb.bsky.social. @mcbseattle.bsky.social PhD.
Scholar| Passionate about Mycobacterial adaptive mechanisms and how they can be targeted to improve TB treatment outcomes| Mycobacterial polyphosphate metabolism| Stress response | TB drug and drug targets Discovery
PhD candidate at @DukeMGM | Former lab tech at #UWMicro | UC Berkeley alum '18 #GoBears | Science enthusiast π©βπ¬ | Plush microbe collector | Views are my own | Treasure those little pockets of joy
Duke MGM PhD Student | Tobin Labπ π¦ π§«
Clemson Genetics and Microbiology β24
NSF GRFP '24
Professor in cell biology at NTNU, Trondheim, Norway. Research on host-pathogen, innate immunity, tuberculosis. Views are my own.
Professor Infectious Disease Epidemiology@Hannover Medical School and Head Department of Epidemiology@Helmholtz Centre for Infection Research, https://helmholtz-hzi.de/epidemiologie; President of the German Society for Epidemiology, https://www.dgepi.de/
PhD student @ i3S Porto | Tuberculosis research
Assistant Professor at Leiden University. Covalent inhibitors and chemoproteomics for antibiotics. Views my own. he/him/his. https://orcid.org/0000-0001-5420-4824
Tries to understand the cellular response against Mtb and improve antiTB drugs delivery. @inserm @InstitutPasteurLille France
Microbes & mucus π€© | Gut Microbial Ecology | Wageningen University, NL
Community of researchers interested in understanding the molecular & cellular mechanisms that pathogens use to colonize their hosts. #microbiology #infection
Section of the French Society for Microbiology
Postdoc at the CSSB Hamburg, studying mycobacterial secretion with #CryoEM and #CryoET. Generally something of a nerd. He/him.
Molecular parasitologist interested in all aspects of gene regulation. Research director at the Pasteur Institute in Lille.
TB researcher at University of Minnesota
PhD candidate in the Helaine lab at HMS BBS, studying salmonella, macrophages, and everything in between. Formerly @ Cambridge Pathology and Middlebury MBBC
Infectious Disease Epidemiologist - Nontuberculous mycobacteria: Research Fellow at the University of Queensland | Microbial Genomics | Also interested in evolution, pathogenesis and #AMR of clinically relevant bacterial pathogens | She/her | Cat lover