Claudia Matthaeus

Thrilled to share a new preprint! 📝 🎉 Lewis lab PhD student Casadora wondered: Do mtDNA synthesis and lipid droplet biogenesis co-occur at the same membrane contact sites? Or can we discern distinct ER-mito contact classes? Evidence suggests the latter, relevant in overnutrition!

Thank you Mike!

Hey Lipid droplet peeps: how can I block lipid droplet synthesis in an easy way? Is there a good working inhibitor that doesn’t mess up many other organelles/ trafficking?

Congrats Rachel!

Haahaa, my PhD Students call papers from 2000 „very old“ 😄, pre-2000 „ancient“

Great work by Mugagga, Lainy and Jess from the Simcox Lab! SCD1 is known to regulate the production of monounsaturated fatty acids and development of diabetes in response of high carbohydrate diet. We showed loss of SCD1 also controls acylcarnitine levels.

How to get tenure in three easy steps!

GBM Lunch: July 16, 12:30
Speaker: Volker Haucke (@volkerhaucke-lab.bsky.social, @fmp-berlin.de)
Title: "Lipid control of membrane dynamics in health and disease"
Chair: Johannes Herrmann (RPTU)
Organized by GBM Study Group "Cellular Organelles"
gbm-online.de/gbm-lunch.html
#GBMLunch

YouTube video by Lab katta Lab katta paperblitz 003 - Lipid transferring protein BLTP2 maintains flexibility of cell membrane

BLTP2 is often overexpressed in breast cancer, we were wondering why. Please check out the latest collaboration of the @retof.bsky.social lab with Subhrajit Banerjee and the Prinz lab:
www.nature.com/articles/s41...

Thank you Lab Katta for the YouTube summary
www.youtube.com/shorts/5Oih-...

Congrats!

Hello microscopy and imaging experts and enthusiasts!
We are looking for a staff scientist to join us here in Geneva to work on microscopy and image analysis projects! See the link for the job announcement (in French and in English).

Please apply and/or repost!

jobs.unige.ch/www/wd_porta...

SNAP-tag2 for faster and brighter protein labeling - Nature Chemical Biology SNAP-tag is a widespread tool for labeling protein for bioimaging. Now, Kühn et al. report SNAP-tag2 with increased labeling kinetics and brightness, which translates into a better performance in live...

📣Paper alert! Interested in faster and brighter protein labeling than before? 👀 @steffi-k.bsky.social & other colleagues have developed an improved tool for labeling proteins with synthetic fluorophores for bioimaging. Also works in STED microscopy 🤩🔬 Congratulations!🥳
www.nature.com/articles/s41...

The 3rd Berlin Single Molecule Biophysics Course will run from 8th to 12th September at the HU-Berlin, Institute of Biology.
Learn about single channels, single molecule TIRF, theory and analysis. Apply by 7th July at bsmbc@icloud.com. Fee waivers and bursaries available.

! Please share widely !

Haahaa, I felt the same way as you! Still waiting how AI solves all our cell biology problems..

Triglycerides are an important fuel reserve for synapse function in the brain - Nature Metabolism Kumar et al. show that under glucose-depleted conditions, neurons can use fatty acids as an alternative source of energy to support synaptic function.

Well what do you know!? This might be the most interesting unorthodox orthodox metabolism paper this year.

Key challenges and recommendations for defining organelle membrane contact sites - Nature Reviews Molecular Cell Biology Membrane contact sites between organelles facilitate the exchange of ions, lipids and metabolites. This Expert Recommendation highlights recent advances in defining the organelle contactome and discus...

Key challenges and recommendations for defining organelle membrane contact sites
www.nature.com/articles/s41...

📣 We also have a second call for a tenure-track Assistant Professor in the field of environmental stress and age-related diseases in our Department at UNIL!! Deadline is as well the 10th of August 2025! Please also re-post and check out this link for more details: wwwfbm.unil.ch/releve/appli...

University: a good idea | Patrick Porter | The Critic Magazine A former student of mine has penned an attack on universities, derived from their own disappointing experience studying Politics and International Relations at the place where I ply my trade. In short...

"A well-delivered lecture isn’t primarily a delivery system for information. It is an ignition point for curiosity, all the better for being experienced in an audience."

Marvellous defence of the increasingly maligned university experience by @patporter76.bsky.social
thecritic.co.uk/university-a...

🧵1/6 — Preprint Alert!
I am super proud to present the latest work of our lab. Earthlings and those just visiting, I introduce you…. EndoNB: A better, smarter and versatile way to study the dynamics of cell surface proteins. 🧪
www.biorxiv.org/content/10.1...

We have a preprint for you

EHD2 forms rings on caveolae necks, in contrast to most EHDs forming helices. We determined its structure on membranes and show that N-term acts as a spacer

By Elena, Vasya @vasiliimikirtumov.bsky.social, Jeff &Oli Daumke www.biorxiv.org/content/10.1...

Cell scientist to watch – Francesca Bottanelli ABSTRACT. Francesca Bottanelli is an Assistant Professor in the Department of Biochemistry at Freie Universität Berlin (Germany). Francesca graduated in Plant Biotechnology from the University of Mila...

Thank you @jcellsci.bsky.social, Sara Morais da Silva and Co for highlighting me as “cell scientists to watch”! It means a lot to me and I feel so honored as you guys are such a great community of amazing cell biologists! journals.biologists.com/jcs/article/...

Text reads "Congratulations to the 2025 Leading Edge Fellows" followed by the Leading Edge logo and www.leadingedgesymposium.org. Below are the headshots and names of the 40 new Leading Edge Fellows. They are Cel Welch Lianna Wat Maria Toro Moreno Sarah Talley Xulu Sun Ines Sturmlechner Virginia Savy Amelie Raz Kali Pruss Caterina Profaci Sarah Pierce Melissa Pamula Kehinde Odufowora Patricia Nano Ariana Musa de Aquino Nour El Houda Mimouni Kathleen Martin Brea Manuel Mable Lam Miri Krupkin Elaine Kouame Megan Kirchgessner Sumin Kim Shubhangini Kataruka Geraldine Jowett Andrea Jones Leanne Iannucci Emily Heckman Allison Girasole Florencia Fernandez Chiappe Tonie Farris Hannah Elam Erin Doherty Xiaoyun Ding Maria Bustillo Julia Brunner Debadrita Bhattacharya Lorena Benedetti Ashley Anderson Krisha Aghi

We are thrilled to announce the 2025 Leading Edge Fellows! 40 outstanding postdoctoral fellows doing pioneering research in a wide range of biological and biomedical disciplines.

Learn more about these exceptional scientists:

www.leadingedgesymposium.org/fellows

Congrats 🎉

I am very excited to share our latest preprint on peroxisome-Golgi interaction in dilp secretion. Great work by lab members @kucharowski.bsky.social, the incredible Marie, @darladr.bsky.social, @buelowt.bsky.social and fantastic collaboration with @jan-ache.bsky.social-Lab and Kuerschner-lab

Excited to share the new work from the Carvalho lab @dunnschool.bsky.social! 🎉This was part of my PhD & a collaboration with the @labvanni.bsky.social & Ernst labs!

Big thanks to everyone involved! 🙌 @jcb.org

Read more: doi.org/10.1083/jcb.... (1/2)

Excited to present first publication from the Joshi lab, now in @jcb.org

Here, we show that phosphatidic acid regulates Pex30 distribution at ER subdomains for lipid droplet biogenesis by binding to dysferlin domain.

rupress.org/jcb/article/...

Oh no! So sorry to hear that!

Molecular machineries shaping the mitochondrial inner membrane Nature Reviews Molecular Cell Biology, Published online: 14 May 2025; doi:10.1038/s41580-025-00854-zThe inner mitochondrial membrane forms cristae, which are crucial for mitochondrial function. This Review explores the protein complexes that regulate cristae dynamics, including remodelling and fusion, and discusses recent structural insights that have increased our understanding of mitochondrial architecture.

ICYMI: New Online! Molecular machineries shaping the mitochondrial inner membrane

The abstract submission deadline for the 2nd edition of our #EMBOLipidDroplets Workshop (21-26 September 2025) is approaching.

Check out the agenda with an amazing lineup of speakers and submit your abstract before 10 June 2025!

@embo.org
@biologists.bsky.social

meetings.embo.org/event/25-lip...

Check out our new roadmap for single cell analyses of adipose tissue at @natmetabolism.nature.com 🧐 Thrilled to share our work put together by great colleagues from Adipose Bionetwork in @humancellatlas.org 🤩 Huge thanks to my fellow co-coordinators @smandrup.bsky.social Evan Rosen and Margo Emont