Hector Peinado

Frontiers | Global hotspots and trends in pre-metastatic niche research: a bibliometric analysis(2005-2024) BackgroundThe pre-metastatic niche (PMN) represents the microenvironment established in target organs before primary tumor metastasis, playing a crucial role...

Proud of our impact in the field!, Special thanks to David and all colleagues 👏👏👏. www.frontiersin.org/journals/imm...

Proteostasis control via HSP90α sustains YAP activity to drive aggressive behaviours in cancer-associated fibroblasts Cancers adapt proteostasis to cope with the burden of misfolded proteins, stabilize key signalling nodes and sustain their malignant behaviour. Tumour stroma is subjected to similar stresses, but how ...

New preprint alert 🚨
We are pleased to share our most recent story about how #CAFs rely on stress responses and proteostasis control to maintain their aberrantly activated state. A work spearheaded by Silvia Dominguez in my lab🧪.
doi.org/10.1101/2025...
🧵1/11

La dieta alta en grasas favorece la metástasis del cáncer de mama en modelos animales La obesidad se asocia a un mayor riesgo de desarrollar cáncer de mama, y a más propensión a que el cáncer se disemine a otros órganos –haga metástasis–. Pero las causas de esta asociación todavía no se entienden bien. Investigadores del Centro Nacional de Investigaciones Oncológicas (CNIO) aportan ahora nuevos datos, al descubrir que una […]

Un estudio liderado por Héctor Peinado @hps2022.bsky.social , del #CNIOStopCancer, descubre que una dieta alta en grasas favorece la metástasis del cáncer de mama en modelos animales. Se publica en @naturecomms.bsky.social

High-fat diet promotes breast cancer metastasis in animal models Obesity is associated with an increased risk of developing breast cancer, and a greater probability for the cancer to spread to other organs – metastasize –. But the causes of this association are still not well understood. Researchers at the Spanish National Cancer Research Center (CNIO) have now provided new data by discovering that a […]

A study led by Peinado @hps2022.bsky.social, at #CNIOStopCancer, discovers that a high-fat diet promote breast cancer metastasis in animal models. It appears in @naturecomms.bsky.social.

Happy to share our latest work @cniostopcancer.bsky.social @naturecomms.bsky.social, defining the impact of a high fat diet on pre-metastatic niche formation - Thaks to my team members involved, collaborators and funding sources, specially @worldwidecancer.bsky.social. www.nature.com/articles/s41...

👉Vamos que nos vamos!! 🚨🚨Tienes hasta ESTE VIERNES 28 (🪐alineamiento de planetas🪐) para apuntarte un CURSO ON LINE sobre todo lo que siempre quisiste saber y nunca te atreviste a preguntar sobre VESICULAS EXTRACELULARES postgrado.ufv.es/curso-de-esp...

Cellular responses to RNA damage RNA plays a central role in protein biosynthesis and performs diverse regulatory and catalytic functions, making it essential for all processes of life. Like DNA, RNA is constantly subjected to damage...

Incredibly timely and informative review article @cp-cell.bsky.social by @jstingele.bsky.social and team on #RNA Damage

www.cell.com/cell/fulltex...

Self-assembling peptide with dual function of cell penetration and antibacterial as a nano weapon to combat intracellular bacteria A nanopeptide with “rapid reach” and “lethal strike” capabilities is identified as an executioner of intracellular bacteria.

Researchers have constructed self-assembled nanopeptides that penetrate cells and target intracellular bacterial infections, which are increasingly difficult to treat due to antibiotic resistance.

Learn more in #ScienceAdvances: scim.ag/414fw2q

If you are working in Extracellular vesicles and metastasis you may want to submit your work to this special issue on EVs in Clinical Experimental Metastasis Journal (Official Journal of the Metastasis Research Society)

link.springer.com/collections/...

Repetitive antigen stimulation in the periphery dictates the composition and recall responses of brain-resident memory CD8+ T cells
www.cell.com/cell-reports...
@cp-cellreports.bsky.social

Sexta edición del curso Online GEIVEX/UFV MOOCS en español - geivex.org/outreach/new... -

Un año más tenemos el Curso de Especialización en Vesículas Extracelulares online.

Nicholas Fabiano, MD
@NTFabiano
Academics are paid nothing for peer review.

Yet journals made a total of over $8.3 billion on article processing charges alone between 2019-2023.

Make it make sense.
x.com/NTFabiano/st...

More than 40% of postdocs leave academia, study reveals Publishing highly cited papers helps postdoctoral researchers to land a faculty job.

More than 40% of postdocs leave academia, study reveals www.nature.com/articles/d41...

Yay!