Teresa Thurston

Excellent opportunity to set up your lab at the Dunn School in Oxford as an ECR.

Excited to Salmonella effector SteE featured on the cover of EMBO reports www.embopress.org/journal/1469...

Salmonella Effector SteE Reprogrammes the Macrophage Regulatory Network to Drive Specific Hyperactivation of STAT3 Target Genes The ability of Salmonella Typhimurium to exploit macrophages as a niche for survival, replication and dissemination is central to its pathogenesis. The effector SteE, which polarises macrophages into ...

We have a new preprint on Salmonella effector SteE! Here we describe how kinase reprogramming drives transcriptional remodelling of the infected macrophage www.biorxiv.org/cgi/content/... - work led by @ines-ddo.bsky.social and fantastic collaboration with @peterwshill.bsky.social

Bacterial effectors mediate kinase reprogramming through mimicry of conserved eukaryotic motifs | EMBO reports imageimageA virulence protein from diverse bacteria switches the amino acid specificity of the eukaryotic kinase GSK3. This kinase reprogramming depends on several short linear motifs that each appear...

How can a Salmonella effector change the specificity of a host kinase? SteE mediates kinase reprogramming via mimicry of conserved eukaryotic-like motifs- doi.org/10.1038/s443... Great collaboration with @katrinrittinger.bsky.social + big thanks to all authors & congrats to lead PDRA Ioanna Panagi!

Yay! Excited for UK Cell Micro 2025

🚨 UK Cell Micro 2025 is here! 🚨

📅 2nd-3rd June 2025
📍 King’s College London

Join us for fun science, networking, and a rooftop social! 🌇🎉

💡 Submit your abstract by 10th April

ukcellmicro.org

We recently had a day of Salmonella-focused fun. Special thanks to @eadirectordndi.bsky.social and PhD student Kelvin Kerring for joining us from Kenya to discuss iNTS. All made possible via the Global hubs fund and @embo.org YIP networking fund. @jayhinton.bsky.social @katrinrittinger.bsky.social

Salmonella effector kinase SteC is activated by host-mediated phosphorylation The pathogen Salmonella , which causes significant human morbidity and mortality, encodes an effector kinase, SteC, which mediates actin polymerisation and cell migration. Given the minimal nature of ...

New preprint on how a minimal Salmonella kinase needs a host kinase to activate it. Work led by @timeshpillay.bsky.social and another great collaboration with @katrinrittinger.bsky.social @crick.ac.uk biorxiv.org/content/10.1...

During my PhD at @crick.ac.uk and @imperialcollegeldn.bsky.social, I explored the molecular interaction between host and pathogen. My question: How have pathogenic bacteria evolved to manipulate their host environment during infection? 🦠https://biorxiv.org/content/10.1101/2025.03.01.640964v1 1/11

The taxonomy & lifestyle of Salmonella Typhimurium

www.microbiologyresearch.org/content/jour...

ICYMI

We are recruiting a new Associate Professor in cell and molecular biology, with a preference for immunology, inflammation and/or infection - all defined broadly

Come and be our colleague!

Deadline 28 Feb, please spread the word!

www.path.ox.ac.uk/vacancy/asso...

Check out the ILESLA PhD programme in Oxford -a great opportunity for a PhD in Life science areas with rotation projects and industry experience too!

We just can't stop recruiting!

Associate professor in cell and molecular biology @dunnschool, with a preference for immunology, inflammation and/or infection - all defined broadly

Come and be our colleague

Deadline 28 Feb, please spread the word

www.path.ox.ac.uk/vacancy/asso...

The David Holden PhD Studentship in Bacterial Pathogenesis at Imperial College London: Molecular Mechanisms in Bacterial Pathogenesis at Imperial College London on FindAPhD.com PhD Project - The David Holden PhD Studentship in Bacterial Pathogenesis at Imperial College London: Molecular Mechanisms in Bacterial Pathogenesis at Imperial College London, listed on FindAPhD.com

Interested in a PhD in bacterial pathogenesis? Then consider applying to the inaugural David Holden PhD Studentship at Imperial inaugural David Holden PhD Studentship (home funded students only). Deadline Jan 31st! www.findaphd.com/phds/project...

Happy 2025 to all!

You want to learn about microbiology from a fantastic lineup of speakers on a beautiful Greek island? PhD students apply now for the @EMBO | @FEBSnews Lecture Course The New Microbiology!
Registration: 1 Apr 2025
Course: 03 – 11 Sep 2025 | Spetses, Greece
meetings.embo.org/event/25-new...

Thank you!

I am super excited that the Thurston Lab will join the #EMBO YIP programme and its amazing community.