SHARE CTD

Meta-analysis of individual participant data: rationale, conduct, and reporting The use of individual participant data instead of aggregate data in meta-analyses has many potential advantages, both statistically and clinically. Richard D Riley and colleagues describe the rational...

#PeerOnSky Article 2! "Meta-analysis of individual participant data: rationale, conduct, and reporting" by Riley et al. (2010). IPD boosts power for subgroups and adjusts for confounders. Read: doi.org/10.1136/bmj.... What challenges do you face in IPD meta-analyses? #OpenScience #MetaAnalysis

A must read work from our network. 👍

🔬 #PeerOnSky starts! “Clinical Trial Participants’ Views of the Risks and Benefits of Data Sharing” by Mello et al. (2018). They found participants value data sharing for science, but worry about privacy breaches. A 2018 perspective still relevant today! Does this reflect current views? #DataEthics

🎉 Hello all! Welcome to #PeerOnSky! It stands as 'Peer discussion on the Sky'. We will dive into cutting-edge research, sparking discussion on BlueSky using the articles discussed within our network. We’ll kick off with a 2018 gem on clinical trial data sharing. #OpenScience #Research #JournalClub

a must read article for the week!

BBQ under the rain

class dynamics

Gottingen City tour!

Group presentation

We worked heavily on coding and biostats exercises, and balanced it out with 'rainy' BBQ evening, City tours, and German/Italian feasts. Datathon1 had it all! 😍Big thanks to the organisers and all participants! #hackathon #OpenScience #ClinicalResearch #biostatistics

🌧️ Just wrapped Datathon1 at UMC Göttingen, from 07 to 11 July! Part of SHARE-CTD, this in-person event brought doctoral students, PIs, and lecturers together for clinical trials, biostats, and data mgmt. Check the Vibes! #SHARECTD #Datathon #Research #biostatistics

The paper @mrcctu.bsky.social offers 8 principles: proactively share results, give participants a choice, make it timely & accessible, involve patients in planning, and more. It’s a call to honor participants’ roles in research. So important for trust! #PatientVoice #OpenScience What do you think?

Sharing clinical trial results with participants: important, expected and possible - Trials Participants in clinical trials should be pro-actively offered the results of trials in which they have participated. This should be done in a way that is accessible and understandable for all partici...

💬 Participants deserve to know! This Trials paper (doi.org/10.1186/s130...) pushes for sharing clinical trial results with participants—because their contributions matter. From a patient’s view, it’s about respect & transparency. Let’s dive in! #ClinicalTrials #Transparency #ShareCTD

We are optimistic about this momentum! What do you think—can these 6 steps transform data sharing in Germany or globally? Share your views or tag a colleague. @sharectd.bsky.social is here to discuss! #ResearchEthics #OpenAccess #ShareCTD #DataSharing

The paper highlights barriers: low sharing rates, GDPR uncertainty, & researcher liability. Solutions include integrating data sharing in ethics applications, mainstreaming consent, & creating data clearing offices. A step toward patient benefit! #ClinicalResearch #Transparency

🔬 New paper alert! BMC study (doi.org/10.1186/s128...) proposes 6 solutions target ethics, registries, & governance to tackles Germany’s clinical data sharing crisis. Only 2% of medical research shares data—time for change! Read on! #OpenScience #DataSharing #ShareCTD

What's your take on this, guys? @cburgwinkel.bsky.social @giulia-varvar.bsky.social @minoo-matbouriahi.bsky.social @obinwanne.bsky.social @gregpapapostolou.bsky.social

Huge thanks for the shoutout, @floriannaudet.bsky.social ! 📊 This Nature paper on anonymization in biomedical research is spot-on for our mission at SHARE-CTD. Balancing data sharing with privacy is key—any thoughts on best practices? @kahin-tai.bsky.social @jifanw.bsky.social @yazidoxx.bsky.social

We enjoyed it too, participating online though. Kudos to the committe and all participants!

The study highlights how widely shared datasets like NHANES can be exploited. It is urging better oversight and that trust in data-sharing is key! What safeguards do you think we need? Drop your thoughts below or tag a colleague @plosbiology.org keen to hear your take! #SHARECTD #OpenData #Integrity

Explosion of formulaic research articles, including inappropriate study designs and false discoveries, based on the NHANES US national health database The combination of AI and national health databases offers opportunities, but may also be exploited by unethical agents. This study shows that there has been an explosion of formulaic research article...

🔍 Fascinating read! This PLOS Biology paper uncovers misuse of the NHANES dataset by potential paper mills—raising red flags on shared data integrity. Not about trials, but a must-discuss for research ethics. Check it: journals.plos.org/plosbiology/... #ResearchEthics #DataIntegrity #OpenScience

🎉 Today’s the day! ICTD 2025 - Rethinking Clinical Trials: Inclusivity in Practice, co-hosted by ECRIN @ecrin.bsky.social & SCReN in Madrid. How do we turn talk into action for inclusive study design? Tune in online—registration & waitlist are full! ecrin.org/ictd-2025 #ICTD2025 #ClinicalTrials

What does this mean for researchers? Share your take! Will this checklist item (e.g., Item No. 6) change how you handle trial data? Let’s discuss—tag a colleague or drop your insights below. #ResearchCommunity #OpenAccess #ShareCTD #DataSharing #ClinicalResearch

Why it matters: Only 57% of French trial results were shared (2012-2022, per STAT News). SPIRIT2025 & CONSORT2025 aim to fix this, aligning with SHARE-CTD’s mission. Better data sharing = reproducible science & public trust. What are your thoughts? #SHARECTD #DataSharing #OpenScience

🎉 Big news for clinical research! SPIRIT2025 just dropped, adding an Open Science section & a new Item No. 6 on data sharing. This pushes transparency in trials—where & how de-identified data, code, & materials will be accessible. Check it: www.consort-spirit.org #OpenScience #ClinicalTrials

It should be last Thursday! Sorry for the typo. #cheers

🎉 Kudos to Giulia @giulia-varvar.bsky.social for her speed talk at "Printemps de la Recherche" last Tuesday! She presented about SHARE-CTD, and her project on re-analysis of pivotal trials in Oncology, to Irset’s 350+ pros. A great moment to showcase open science in medicine!🔬
#SHARECTD #OpenScience

🙌 Big props to our SHARE-CTD scientist featured in STAT News! His insights on boosting clinical trial transparency in France (only 57% results shared, 2012-2022) are key to open science. 🔬 #SHARECTD #OpenScience #ClinicalTrials #DataSharing

For those of you who are interesed, please join and register

💬 We want to hear from YOU.
Are you a:
👨‍🔬 Researcher?
👩‍⚕️ Clinician?
🧑‍💼 Policymaker?
🤔 Just curious?
This space is for discussing how data sharing can shape better healthcare.

We’ll keep you posted right here on Bluesky.
Follow us to stay involved. Let’s share!
#ScienceCommunication #DataSharing

📊 What does this look like in practice?
🔁 Re-use of anonymized trial data
🔎 Meta-research and systematic reviews
🤝 Informed consent innovation
⚙️ Building FAIR & open platforms
All focused on ethical, efficient sharing.
#FAIRData #ClinicalResearch #DataSharing

🌍 We’re based all across Europe!
Our network includes:
@lmumuenchen.bsky.social | @bihatcharite.bsky.social |
@umcutrecht.bsky.social | @rennesuniv.bsky.social | @hcl-recherche.bsky.social | @meduniwien.ac.at
and others
Together, we’re training 11 diverse PhD students. #ResearchNetwork

🎯 Our goal is simple:
💬 Build a stronger culture of sharing in clinical research.
👩‍🎓 Train a new generation of young researchers who practice the value of openness and rigour.
📈 Improve public trust in science.
#FutureOfResearch #MetaResearch #DatSharing

But it’s not always easy :(
Data sharing comes with big challenges:
🧩 Complex regulations
🔒 Patient privacy
💾 Technical interoperability
⚖️ Ethical concerns
SHARE-CTD brings together young researchers, established institutions & policymakers to tackle them.
#ResearchEthics #DataAccess #Collaboration