Philip Fowler

Our team wore blue for World Antimicrobial Awareness Week 2025💙

Research into how resistance emerges, spreads and can be prevented is vital. Our group works to understand these processes and develop better tools to detect, monitor and combat antimicrobial resistance.

#WAAW @oxfordbrc.bsky.social

Subpopulations in clinical samples of M. tuberculosis can give rise to rifampicin resistance and shed light on how resistance is acquired AbstractObjectives. WGS has become a key tool for diagnosing Mycobacterium tuberculosis infections, but discrepancies between genotypic and phenotypic drug

For #WorldAntimicrobialAwarenessWeek, we introduce our recent paper on antibiotic-resistant subpopulations in TB.
TB may be one of humanity’s oldest diseases, yet it still kills over 1M people yearly. As resistance spreads, knowing each patient’s resistance profile before treatment is vital. 🧬💊

Antimicrobial resistance occurs when bacteria, viruses, fungi & parasites change over time - leading to medicines being less effective against them.
Here you see bacteria growing and antibiotics (the small discs) which kill the bacteria...unless they are resistant!
#WAAW #AMR @oxfordbrc.bsky.social

Bash The Bug (@BashTheBug) / X Bash The Bug (@BashTheBug) / X

Are you interested in infections, the micro-organisms that cause them and antimicrobial resistance? So are @bashthebug.net and they're looking for new members to join their patient & public group. More info: bashthebug.net/lay-represen... Deadline 27 Nov @ouhospitals.bsky.social @medsci.ox.ac.uk

New paper: What can subpopulations tell us about rifampicin resistance? Last Thursday this work which we'd previously preprinted looking at looking at rifampicin-resistant subpopulations in clinical M. tuberculosis samples was published in JAC-Antimicrobial Resistance. If...

New paper by @vbrunner.bsky.social looking at detecting rifampicin resistant subpopulations in M. tuberculosis infections using genetics and putting a lower limit on the proportion that arose due to secondary infections.

bit.ly/47rwf42

@modmedmicro.bsky.social
@oxfordbrc.bsky.social

Pleased to see this pre-printed, highlighting the completeness/accuracy of @nanoporetech.com long-read genome assembly for clinical Enterobacterales: www.biorxiv.org/content/10.1...

Thanks to colleagues @modmedmicro.bsky.social, @ukhsa.bsky.social, @genewiz.bsky.social and @oxfordbrc.bsky.social!

Nanopore long-read only genome assembly of clinical Enterobacterales isolates is complete and accurate Whole bacterial genome sequence reconstruction using Oxford Nanopore Technologies ('Nanopore') long-read only sequencing may offer a lower-cost, higher-throughput alternative for pathogen surveillance...

Great new work from #DotNagy @modmedmicro.bsky.social - she tool 96 clinical isolates from the NEKSUS study and sequenced with both Illumina and Nanopore - question was, can we do away with hybrid sequencing for the rest of the study?
www.biorxiv.org/content/10.1...

'Linking life expectancy to the bacteria in our gut: A final year undergraduate project'.

Akika investigated how the gut microbiome influences longevity, with fieldwork in Nagano, Japan—home to the country’s longest-living population.

Read the blog post here ➡️ bashthebug.net/2025/08/22/l...

I’ve just watched all of MurderBot and definitely recommend

Brilliant! Yes a timeless test which stops on Mondays instead of Sundays

Brilliant - signed up.

Always thought cycling shared with cricket the curious feature that one can listen to someone talking about what is going on (like TMS) and that is perhaps even better than watching it.

The TdF is after all even longer than a Test Match.

Bit over 24 hours left to apply for these two posts to help us develop pipelines to process pathogens..!

Senior Bioinformatic Engineer
bit.ly/4ecl0hF

Senior Biostatistical Researcher
bit.ly/4kRfZxI

Grade 8 or 7, depending on experience
closing date: noon Tues 8 July

Poster illustration showing the back of a bicycle rider riding on the side of a street and running out of room as a truck driver drives so close to the curb as to make the bicyclist lose control.

Mind That Cyclist! Give Him Room
1950
Artist: Roland Davies

Job advert to come and work with me on tuberculosis closes tomorrow (Friday) at noon!

Part of #OxCOD4TB

bit.ly/4ndKOhF

@ndm.ox.ac.uk @modmedmicro.bsky.social
@oxfordbrc.bsky.social

Congratulations to the winners of the poster prizes, Elliott Rogers and Iva Grujic, yesterday at the 3rd #Dx4LMIC conference at @reubencollege.bsky.social !

Andrew Singer gets day two underway at the #Dx4LMICs conference at @reubencollege.bsky.social

Lionel Tarassenko introducing Vivian Lee who is giving the after dinner speech at #Dx4LMICs conference at @reubencollege.bsky.social

Jospeth Matovu: HIV self testing among fishermen

@reubencollege.bsky.social #Dx4LMICs

Arjuna Sen talking about equity in epilepsy at @reubencollege.bsky.social

#Dx4LMICs

@gariclifford.bsky.social talking about how extensive cell phone coverage was in China 20 years ago:

“If you can drive a truck up a road there will be a cell phone tower at the end of it”

#Dx4LMICs @reubencollege.bsky.social

Joshua Kibera gets us underway at #DxLMICs at @reubencollege.bsky.social

Any questions DM me

All ready for day one of the third #Dx4LMICs conference at @reubencollege.bsky.social !

AlphaGenome: AI for better understanding the genome Introducing a new, unifying DNA sequence model that advances regulatory variant-effect prediction and promises to shed new light on genome function — now available via API.

deepmind.google/discover/blo...

Drowning Doesn’t Look Like Drowning Drowning is not the violent, splashing call for help that most people expect.

Thanks for the reminder @janemunday.bsky.social. Every summer, I repost this article DROWNING DOES NOT LOOK LIKE DROWNING. To date, I know of FOUR kids who were saved after someone who'd clicked on the link learnt how to spot actual drowning. Take time to read and pass on.

slate.com/technology/2...

And that's a wrap on #ESM2025! A huge thank you to our incredible community of scientists, speakers, and organizers who made this week unforgettable. The future of mycobacteriology is bright! See you all in 2026! 👋 #Tuberculosis #Science

Three posts all closing next week!

Senior Biostatistical Researcher bit.ly/4kRfZxI
Senior Bioinformatic Engineer bit.ly/4ecl0hF
both Grade 8 or 7, closing noon Wed 2 Jul

Computational Mycobacteriologist
Grade 7, closing noon Fri 4 Jul bit.ly/4ndKOhF

@medsci.ox.ac.uk

YouTube video by Eh!woza Healthcare in Rural South Africa | The Clinic that Crossed the River

[TRAILER]🎥 “The Clinic That Crossed the River” is a film by young men from Xhora Mouth, Bulungula in the Eastern Cape. This film tells a story of the Bulungula community and their long, difficult journey to access healthcare.

Check link for more: youtube.com/watch?v=Igh7...

Come and work with me and use the 53,897 samples of M. tuberculosis we have collated to help tackle this important disease!

We are part of the OxCoD4TB consortium that is developing new therapeutics for tuberculosis.

Grade 7, funding until 28 Feb 2028, deadline noon Fri 4 July

bit.ly/4ndKOhF

@vbrunner.bsky.social doing her pitch for her poster at #ESMyco!

@modmedmicro.bsky.social