Kevin Lynch

Nebraska 🪶

The structure of human sweetness A single taste receptor initiates our reactions to both sugars and artificial sweeteners, triggering a signaling process that drives our intense attraction to sweet foods. Single-particle cryo-EM reve...

🧪🍎📃
Attracted to sweet food? 🍬

Blame the sweet taste receptor in your mouth!

It recognizes sugars and artificial sweeteners, triggering the reactions behind our love for sweets.

And its structure was just revealed: www.cell.com/cell/fulltex...

Bonus: a nice graphical abstract!

Will you pease do 6 minutes Charlotte? 😂

Hey @mcuban.bsky.social, I know you're probably being inundated with funding requests right now, but this would be really fun and impactful. It's the kind of thing that could easily be an iconic moment for this era.

Brian Eno 2h. On the Arrest of Young People at a Quaker Meeting House Last night, six young people were arrested by police during a peaceful gathering at a Quaker Meeting House. They had assembled to talk, reflect, and organise around two issues of overwhelming moral gravity: the climate emergency, and the continuing destruction in Gaza. That the police chose to forcibly enter a Quaker space-a site known throughout history for its deep commitment to peace and nonviolence—is both alarming and telling. These young people were not disrupting the peace. They were enacting it. We live in a time where the greatest threats to our future go unchallenged by those in power, while those who speak out are increasingly met with suspicion, hostility, and force. When the state begins to treat moral concern as criminal intent, we should all be paying close attention. The people arrested last night were not extremists. They were citizens who care-young people who see the interconnected crises of climate collapse and human suffering and refuse to turn away. They gathered not in violent defiance, but in peaceful conscience. I stand with them. I believe their voices are not only valid, but vital. If the institutions meant to protect us cannot bear to hear these voices, then it is not the protesters who are disrupting order—it is the silence of those who look away. - Brian Eno

Worth sharing with alt text. Brian Eno's response to the Quaker arrests.

Read this.

I NEVER UNFRIEND PEOPLE OVER POLITICS A Handy Guide to Understanding my Social Media Behavior Here are some examples of Political Issues "Should we levy another School tax this year?" "Is the maximum building Height for this zone Appropriate, or should We alter it?" "Do we need a light rail For our city?" "How much of our state Budget should go to road Upkeep this year?" I don't unfriend people Over stuff like this Here are some examples of Not Political Issues "Are gay people human beings?" "Should women be paid the same As men?" "Are Nazis bad?" "Is extortion bad?" "Are war crimes bad?" "Why can't presidents abuse power?" "Are black people bad?" I unfriend people over stuff like this

A useful cheat sheet “I never unfriend people over politics”
(h/t; mastodon.world/@BrianJopek/...)

If you see this, quote post with a photo from your gallery

Normalize pronouncing DOGE as DOUCHE.

Blue Heron and Red Autumn Leaves

Spotted along Jordan Creek in North Whitehall Township.

#photography #wildlifephotography #birds
#lehighvalley

Prints: lehighvalleylandscapes.com/featured/blu...

How about a multi state AG compact to form a non-shadow prosecution engine, fill the courts with opposition

Darling and I are seeing the #Brutalist, 3 hours 15 minutes, at the theatre. I was told I should bring my CPAP 😴🥱

The image shows an old wooden bridge spanning a river. The bridge has a distinctive arched design with visible laminated beams supporting its structure. There are no people or vehicles on the bridge at this moment. The surrounding environment includes trees and what appears to be a roadway leading up to the bridge. The weather seems overcast

Eagle River, Keweenaw

"When we begin to care about creatures that most people think are lowly, we become better people. We weave ourselves more tightly into the tapestry of the world around us, and we arm ourselves for the fight to save the world."

@rosemarymosco.com: "When we begin to care about creatures that most people think are lowly, we become better people. We weave ourselves more tightly into the tapestry of the world around us, and we arm ourselves for the fight to save the world."

In the process of landing, hundreds of snow geese swirl downward into a harvested corn field

The Snow Geese came in from the east, large flocks are passing over #LehighValley #Birds

So, just yesterday, I loaded the laundry machines owners manuals PDFs into my ChatGPT and started to ask questions about doing laundry. It was quite helpful. Ever since the days of blinking 12:00, it’s the UI that is suffering, the machine is just a machine

Happy New Year friends, I am switching from mugs to cups for my coffee & tea!Make 2025 #YourSize #tea #coffee

I remember when… you could peg someone as not-smart for repeating a lie. Lying seems to be mainstream these days. I down-vote dishonest dealings

Heroes' Square

maps.apple.com?address=Hero... This become more real when I see it on my map, solidarity with folks asserting collective agency

Twenty years ago today, a massive earthquake struck the coast of Indonesia and sent a tsunami hurtling across the Indian Ocean. What followed was one of the most extraordinary online organizing campaigns I'd ever seen.

Israel Closes Embassy in Ireland

I support the worker right to unionize, I’ll return when equity is on the menu

An M dwarf star with the text: "I am not a toy. I am not a Christmas present. I am a 10 trillion year commitment"

Think twice before gifting someone an M dwarf this holiday season

Court order text. Link to follow

Court order text. Link to follow

Court order text. Link to follow

Court order text. Link to follow

BREAKING: court finds NSO Group liable for #Pegasus hacking of #WhatsApp users.

Big win for spyware victims.

Big loss for NSO.

Bad time to be a spyware company.

Landmark case. Huge implications. 1/ 🧵

A six-panel cartoon titled "real and implied birds". In the two panels in the top row, there's a rough legged-hawk sailing through the sky, next to a smooth legged hawk, which has smooth human legs. In the second row, there's a great-crested flycatcher looking dapper, next to an ok-crested flycatcher that has just a slightly less nice crest. In the third row, there's a mountain chickadee standing up on stones, next to a valley chickadee peeking out from a dip between stones. In the fourth row, there's a least bittern standing in some reeds, next to a most bittern that is enormous and stomping through a city, with people running in fear, helicopters overhead, and an overturned car on fire.

Another thing I made this year: Real and implied birds.

On my first visit to Taiwan, as I ascended in the elevator, it struck me that I was not only the tallest person there but also completely unable to read, write, or communicate with anyone around me.

Adding 10 provinces to the USA would likely change the balance, can we add PR and DC too?

Someone in editorial at Chemosphere should be ashamed of this - the authors too.

60 * 7,000 != 42,000

Not complicated math, and not a typo as the authors say - this is a conclusion that no longer applies. This is a “check your work” example up there with the “cite the crappy Gabor paper?” thing. 🧪

Hayden, as I watch the data flow across the map, patterns and convergences start to emerge—it’s fascinating. Building AI models to illuminate transit patterns seems like an exciting challenge. Do you have any recommendations on who might already be working on something like this?

These four men were going to be executed today by the Assad regime. “Our executions were going to be half an hour ago.”