ambrains

🚨Preprint!🚨 So excited to share my 1st major study as a postdoc at @holmeslab-bhi.bsky.social!🤘

www.biorxiv.org/content/10.1...

Using a transdiagnostic framework, we found that brain network dynamics were able to discriminate individualized psychiatric symptom profiles with high accuracy 🧵1/9👇

High–resolution laminar recordings reveal structure–function relationships in monkey V1 The relationship between the structural properties of diverse neuronal populations in the monkey primary visual cortex (V1) and their functional visual processing in vivo remains a critical knowledge ...

On behalf of Nicole Carr: new preprint from the Chand/Moore labs! High-resolution laminar recordings reveal structure-function relationships in monkey V1.

1/4

www.biorxiv.org/content/10.1...

Info theory offers powerful measures for capturing complexity & interaction among elements of a complex system, like the brain! 🧠 Here's our new unified reference for key info-theoretic time series measures ft. 📊 visuals, ➗equations, & 💬descriptions:

arxiv.org/abs/2505.13080

🧠💊New preprint differentiating antipsychotic medication vs. illness effects on cortical thickness in people w/ psychosis.

Finding: People receiving placebo show prominent cortical thinning over 1st year of illness, whereas those receiving antipsychotics do not. 1/3

www.medrxiv.org/content/10.1...

Check out our new special issue on cognitive flexibility @coolscontrol.bsky.social: authors.elsevier.com/a/1l4vl8MqMi...

Inferring macroscopic intrinsic neural timescales using optimal control theory The temporal evolution of brain activity relies on complex interactions within and between brain regions that are mediated by neurobiology and connectivity. To understand these interactions, many larg...

🧠 Check out the new preprint from Dr. Linden Parkes, Assistant Professor of Psychiatry at Rutgers Robert Wood Johnson Medical School and Core member of Rutgers Center for Advanced Human Brain Imaging Research (CAHBIR) and BHI! @lindenmp.bsky.social
www.biorxiv.org/content/10.1...

a man applauds with the words so proud of my team above him ALT: a man applauds with the words so proud of my team above him

Excited to share the first major piece of work and preprint from my lab! Led by Jason Kim! 🥳🎉🤘

www.biorxiv.org/content/10.1...

fMRI must break out of its silo We need to develop research programs that link phenomena across levels, from genes and molecules to cells, circuits, networks and behavior.

The scientific community needs to develop processes to support, hire and retain researchers whose work sits between traditional fields of study, writes @avramholmes.bsky.social

#neuroskyence

www.thetransmitter.org/future-of-fm...

fMRI must break out of its silo We need to develop research programs that link phenomena across levels, from genes and molecules to cells, circuits, networks and behavior.

Future of #fMRI:

To make a meaningful contribution to neuroscience, fMRI must break out of its silo

www.thetransmitter.org/future-of-fm...

#neuropsychology #cognition

The molecular and cellular underpinnings of human brain lateralization Hemispheric specialization is a fundamental characteristic of human brain organization, where most individuals exhibit left-hemisphere dominance for language and right-hemisphere dominance for visuosp...

🚨 New #preprint: The molecular and cellular underpinnings of human brain lateralization

🔗 doi.org/10.1101/2025...

🧠 We identify an acetylcholine-norepinephrine axis underlying functional lateralization, along with mitochondrial and cellular correlates. 🧵1/9👇

#neuroskyence

The molecular and cellular basis of human brain lateralization. Latest paper from @holmeslab-bhi.bsky.social led by @loiclabache.bsky.social. @rutgersbhi.bsky.social, @cahbir.bsky.social

The molecular and cellular underpinnings of human brain lateralization Hemispheric specialization is a fundamental characteristic of human brain organization, where most individuals exhibit left-hemisphere dominance for language and right-hemisphere dominance for visuosp...

Excellent preprint by a great team @loiclabache.bsky.social @sidchop.bsky.social @xi-hanzhang.bsky.social @avramholmes.bsky.social on the underpinnings of human brain lateralization: an Acetylcholine-Norepinephrine axis for functional lateralization + mitochondrial substrates & cellular correlates🧪

"To make a meaningful contribution to #neuroscience, #fMRI must break out of its silo."

My latest attempt to convince you of the importance of multi-scale approaches for the study of the human brain.

fMRI must break out of its silo We need to develop research programs that link phenomena across levels, from genes and molecules to cells, circuits, networks and behavior.

Until recently, in-vivo brain imaging has largely been absent from… integrative efforts, limiting the opportunities to contribute our discoveries, theories or vision toward a comprehensive view of brain function, writes @avramholmes.bsky.social.

#neuroskyence

www.thetransmitter.org/future-of-fm...

fMRI must break out of its silo We need to develop research programs that link phenomena across levels, from genes and molecules to cells, circuits, networks and behavior.

🧠 Featured Insights! Dr. @avramholmes.bsky.social, Associate Prof of Psychiatry at RWJMS and Core Member of BHI & CAHBIR, shares insights on #fMRI and the need for integration across #neuroscience disciplines in @thetransmitter.bsky.social
www.thetransmitter.org/future-of-fm...
#neuroimaging

New paper in Imaging Neuroscience by Vaanathi Sundaresan, Anastasia Yendiki, et al:

Self-supervised segmentation and characterization of fiber bundles in anatomic tracing data

doi.org/10.1162/imag...

Temporal fMRI Dynamics Map Dopamine Physiology Spatial variations in dopamine function are linked to cognition and substance use disorders but are challenging to characterize with current methods. Because dopamine influences blood vessel dilation,...

Interested in dopamine? Have fMRI data? We’ve identified a temporal BOLD feature that carries rich information about dopamine physiology. This measure, obtainable from resting-state and task fMRI, opens new ways to indirectly probe dopamine’s role in cognition and disease. 1/n tinyurl.com/bddyz67b

A network correspondence toolbox for quantitative evaluation of novel neuroimaging results - Nature Communications Here, the authors present the Network Correspondence Toolbox, which enables researchers to examine and report spatial correspondence between their neuroimaging results and widely used brain atlases.

It's finally here! Use the Network Correspondence Toolbox to help contextualize your neuroimaging findings 🧠

👇

Multimodal precision MRI of the individual human brain at ultra-high fields | bioRxiv www.biorxiv.org/content/10.1...

PsyPost covered @lydiaquq.bsky.social's new paper linking internalizing/externalizing symptoms to distinct features! Check it out ⬇️
🖇️https://www.psypost.org/scientists-identify-distinct-brain-patterns-linked-to-mental-health-symptoms

#SciComm #Neuroscience

🚨New lab preprint alert!🚨

Grab a drink, sit down, and let me walk you through the moment-by-moment process of how information loops through basal ganglia circuits during a decision.

(Link at the end of the thread)

1/9

🧩New study: "Network Constraints on 𝘪𝘯 𝘷𝘪𝘷𝘰 Synaptic Alterations in Schizophrenia"

medrxiv.org/content/10.1...

We map a prominent brain-wide pattern of synaptic defects in people with Schizophrenia using PET, then model the molecular, cellular & connectomic features shaping this pattern 🧵1/3👇

Connectivity profile and function of uniquely human cortical areas Determining the brain specializations unique to humans requires directly comparative anatomical information from other primates, especially our closest relatives. Human ( Homo sapiens ) (m/f), chimpan...

Always thought we should use connectivity blueprints to investigate differences between human, chimpanzee, and macaque brains? www.jneurosci.org/content/earl... For Katherine Bryant’s latest masterpiece.

New paper in Imaging Neuroscience by Yaotian Wang, Tingting Zhang, et al:

Analysis of functional connectivity changes from childhood to old age: A study using HCP-D, HCP-YA, and HCP-A datasets

doi.org/10.1162/imag...

Cerebral blood perfusion across biological systems and the human lifespan | doi.org/10.1101/2025...

How does blood perfusion map onto canonical features of brain structure and function? @asafarahani.bsky.social investigates ⤵️

Rhythms and communication in the brain
doi.org/10.1016/j.ti...

Current Directions in Psychological Science article entitled More Than Just a Phase: Adolescence as a Window Into How the Brain Generates Behavior

Excited to share this brief review where @katieinsel.bsky.social & I discuss studying adolescence to understand how brains work! We highlight avenues for future collaborative work at the intersection of cognitive, computational, & developmental neuroscience 🧠
journals.sagepub.com/doi/10.1177/...

I'm very excited to share my PhD work "Motifs of brain cortical folding from birth to adulthood: structural asymmetry and folding-functional links". We identified and characterised the lobe-wise folding patterns using both 1110 young adults (HCP) and 781 term-age neonates (dHCP & BIBS studies). 1/9

Noise in Cognition: Bug or Feature? pubmed.ncbi.nlm.nih.gov/40035520/ "We propose that the brain approximates probabilistic inference... using randomness to drive its exploration of alternative hypotheses"

There have been people less than helpful in my journey here. I wanted to acknowledge those too, bc I know I am not unique in this experience. No thank you to the physics study assoc that made me sing songs about how women couldn't study physics without sleeping with the professor, the day I stepped into university life. No thank you to the 5th year physics student that decided to assign me a stripper name within the first minute of meeting me in the physics coffee corner in my first year. No thank you to the technician that was responsible for onboarding me on the use of the cluster in my third year who raised his eyebrows and asked me if that meant I was some sort of computer girl. No thank you to the senior researcher that sent me utterly inappropriate texts after a conference, then proceeded to apologise months later by telling me they had not been meant for me anyway so no hard feelings remain hopefully And no thank you to him for attending every conference I've been to since. No thank you to the people who told me that it was surprising that I was doing a PhD since I was a girl. No thank you to the man who mistook me for a coffee lady at a conference, and after having to correct him two times that I did not work there, responded with you should consider it. No thank you to the researcher that asked me what I was wearing underneath my outfit during a conference. No thank you to the physicist who declared to a room full of other physicists that biologists don't know how to design an experiment. No thank you to the people who have called me scary instead of strong and intimidating instead of intelligent. And finally, no thank you to the exec board of the TU Delft, whose knee-jerk reaction to being held up a mirror about the social safety at the university, was to sue the party holding up the mirror instead of looking at the problems they highlighted. ... You have made me feel like I do not belong in science & I cannot forgive you for that.

A friend included this anti-acknowledgement section on her PhD thesis. She also added the proposition: “Systematic bullying and undermining of girls and women in STEM starts early on and is the reason why they do not stay in science and related fields.”
Absurd we still need to go through this
🧪👩‍🔬