Fantin Mesny's Avatar

Fantin Mesny

@mesny.bsky.social

Post-doctoral researcher in the group of Prof. Marcel van der Heijden (University of Zürich, Switzerland). Fungal biology | Soil & plant microbiota | Ecology & evolution | Plant-microbe-microbe interactions | Genomics | ...

602 Followers  |  403 Following  |  45 Posts  |  Joined: 05.01.2024  |  2.1831

Latest posts by mesny.bsky.social on Bluesky

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Starship giant transposons dominate plastic genomic regions in a fungal plant pathogen and drive virulence evolution Nature Communications - Giant transposons, known as ‘Starships’, mediate horizontal gene transfer between fungal genomes. Here, Sato et al. show that Starships occupy genome regions...

📣 Happy to see the journal publication 📄 of our work on Starships 🚀 in Verticillium fungi: terrific work led by @yukiyosato.bsky.social
rdcu.be/exBSp

24.07.2025 10:40 — 👍 103    🔁 56    💬 4    📌 1
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Finally, @adnroide.bsky.social presented his PhD work on receptor engineering by introducing pikobody domains in NLR proteins. This approach allowed him to generate potato plants that can recognize the effector Avrblb2 of Phytophtora infestans.

20.07.2025 16:41 — 👍 2    🔁 0    💬 0    📌 0
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Independent researcher @ccilelorrain.bsky.social presented how she used GWAS in the field to identify multiple novel effectors of Zymoseptoria tritici, which could be validated experimentally!

20.07.2025 16:37 — 👍 1    🔁 1    💬 1    📌 0
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Great presentation (and poster!) by @anikadamm.bsky.social, describing two nematode transcription factors that regulate effector gene expression at different infection stages.

20.07.2025 16:35 — 👍 1    🔁 1    💬 1    📌 0
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Young group leader Talia Karasov (University of Utah) gave an insightful plenary talk, showing that the genomes of Pseudomonas pathogens encode highly specific tailocins that drive intra-genus competition between pathogens. Non-pathogens seem mostly safe!

20.07.2025 16:32 — 👍 1    🔁 0    💬 1    📌 0
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Trang Phan (@zmbp-tuebingen.bsky.social) found that a Xanthomonas pathogen activates the expression in Citrus leaves of a fruit ripening enzyme that digests leaf xylan, which consequently triggers T2SS effector secretion.

20.07.2025 15:53 — 👍 3    🔁 1    💬 1    📌 0

In the same concurrent session, @mcdonaldmeganc.bsky.social (group leader at the University of Birmingham) showed how transposons drive effector gene evolution (gene multiplication and inactivation) in Pyrenophora fungi. Impressive findings!

20.07.2025 15:49 — 👍 1    🔁 0    💬 1    📌 0
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Great talk by @racquelsingh.bsky.social who presented how she dissects sequence variation in conserved "Hrp box" promoters of T3SS effector genes in Pseudomonas syringae.

20.07.2025 15:46 — 👍 4    🔁 0    💬 1    📌 0

Coming back from 5 days of great science at #2025ISMPMI, I wanted to share some of my highlights, and particularly to mention my favourite presentations by early career researchers.

A thread 🧵 ⬇️

20.07.2025 15:43 — 👍 30    🔁 8    💬 1    📌 0
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Aphid effectors suppress plant immunity via recruiting defense proteins to processing bodies Aphids hijack plant immunity via p-bodies, but plants fight back with a heat shock protein in an unexpected twist on defense.

Our paper is now online in Science Advances! Congrats @saskiahogenhout.bsky.social @johninnescentre.bsky.social and all coauthors!
www.science.org/doi/10.1126/...

17.07.2025 01:37 — 👍 58    🔁 24    💬 0    📌 0
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Great talk by @teamthomma.bsky.social who shows that effectors have antimicrobial activities that are ancesteral - other functions within the host have evolved later on to suppress immunity in plants #2025ISMPMI

17.07.2025 16:43 — 👍 26    🔁 8    💬 2    📌 0

#2025ISMPMI my poster is up! If you are interested in how a family of plant endogenous peptides can act as both signaling and antimicrobial peptides, pass by my poster P-222 on Thursday afternoon.

16.07.2025 08:49 — 👍 18    🔁 5    💬 0    📌 0
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My poster is up at #2025ISMPMI. Come by P-372 Thursday afternoon if you are interested in fungal evolution, effectors and microbial competitions!

More research by @teamthomma.bsky.social at P-091, P-170, P-299, P-317, P-337 and P-388.

16.07.2025 06:27 — 👍 43    🔁 10    💬 1    📌 1

I would be happy to join, if you agree!

15.07.2025 10:23 — 👍 1    🔁 0    💬 1    📌 0
The fungal effector AvrStb6 regulates the wheat pathobiome Zymoseptoria tritici, the causal agent of the foliar disease Septoria tritici blotch (STB), is a major wheat pathogen in Europe. Although several wheat resistance (R) genes have been identified, Z. tr...

🧪⚔️ When a fungal effector tries to coexist with plant apoplastic bacteria

My poster’s not up until Thursday, but you can already check it out on Zenodo 👀
📎 zenodo.org/records/1585...

🧾 Poster P-166, Thur 17th, 1:30 pm
#2025ISMPMI

14.07.2025 14:38 — 👍 17    🔁 9    💬 0    📌 0
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Happy to be back in Cologne for #2025ISMPMI !

13.07.2025 19:34 — 👍 14    🔁 1    💬 0    📌 0

Wow, congratulations Paloma! Well deserved 😊

08.07.2025 10:01 — 👍 1    🔁 0    💬 1    📌 0
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Hot off the printer!

Our lab will be introducing PHYTOMap to the MPMI community. Interested in spatially mapping both microbiomes and plant gene expression? Come see our posters at #2025ISMPMI

P-315 by @siyusong.bsky.social
P-441 by @hsuanpai.bsky.social

07.07.2025 17:45 — 👍 38    🔁 16    💬 2    📌 1
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The Swiss Mycology Symposium is getting started at @wslresearch.bsky.social in Birmensdorf!

27.06.2025 07:34 — 👍 7    🔁 1    💬 0    📌 0
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We are excited to share our new story with you! We show how losing a binding domain can flip an antimicrobial fungal effector into a host immune suppressor, highlighting functional specialization along the saprotrophy-to-symbiosis continuum. Read more: www.biorxiv.org/content/10.1...

20.06.2025 17:25 — 👍 29    🔁 12    💬 0    📌 0

Last week, our latest @biorxivpreprint.bsky.social preprint was released, a joint-venture of @antonkraege.bsky.social & @wolki95.bsky.social and co-directed by @nicksnelders.bsky.social a 🧵

16.06.2025 13:24 — 👍 34    🔁 23    💬 2    📌 0

Happy to share our work on a recombinant interspecific smut hybrid of two fungal maize pathogens which helped us to understand how the regulation of effector genes determines infection style and tumor formation. Thanks to Gunther Doehlemann, Weiliang Zuo & Tom Winkler!

www.cell.com/cell-reports...

15.06.2025 06:06 — 👍 9    🔁 4    💬 0    📌 1

Undermining the cry for help: The phytopathogenic fungus Verticillium dahliae secretes an antimicrobial effector protein to undermine host recruitment of antagonistic Pseudomonas bacteria https://www.biorxiv.org/content/10.1101/2025.06.09.658588v1

11.06.2025 23:03 — 👍 14    🔁 11    💬 0    📌 1

Cool story, congrats Lara!

07.06.2025 09:30 — 👍 0    🔁 0    💬 1    📌 0
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Cooperation between a root fungal endophyte and host-derived coumarin scopoletin mediates Arabidopsis iron nutrition Iron acquisition is a critical challenge for plants, especially in iron-deficient soils. Recent research underscores the importance of root-exuded coumarins in modulating the root microbiome community...

Curious about my PhD research @parkergroup.bsky.social? The paper is available as preprint on bioRxiv now!
🔬 The interaction between scopoletin and fungal endophyte F80 rescues plant growth under iron-limiting conditions by resolving the iron mobility bottleneck.
📝 www.biorxiv.org/content/10.1...

07.06.2025 08:27 — 👍 45    🔁 21    💬 2    📌 1

I can only recommend.

• Unique topic at the forefront of plant pathology
• Opportunities to develop your own research ideas
• Great scientific environment
• Definitely a lab where you get to learn a lot!

05.06.2025 07:02 — 👍 6    🔁 2    💬 1    📌 0
Legume-specific recruitment of rhizobia by hyphae of arbuscular mycorrhizal fungi The legume-rhizobia symbiosis possesses great potential for sustainable agriculture because of its ability to fix atmospheric nitrogen, reducing crop dependence on nitrogen fertilizers. Rhizobia recognize the host legume through flavonoids released by the roots. These signals are detected by bacteria typically over a few millimeters. Recent research has shown that arbuscular mycorrhizal fungi extend this recognition beyond 15 cm by transporting flavonoids along their hyphae. In soil, common mycorrhizal networks linking plants are formed by arbuscular mycorrhizal fungi. We hypothesized that such networks linking different legumes can transmit host-specific signals, guiding rhizobia to their appropriate hosts. Using in vitro and greenhouse microcosms, we linked Medicago truncatula and Glycine max via a common mycorrhizal network of Rhizophagus irregularis and inoculated GFP-labeled Sinorhizobium meliloti and mCherry-labeled Bradyrhizobium diazoefficiens on the hyphae. S. meliloti preferentially migrated towards M. truncatula, whereas B. diazoefficiens preferentially migrated towards G. max (155 ± 8 and 13 ± 3 nodules, respectively). This was confirmed in the greenhouse with a higher concentration of S. meliloti (2.1-2.5 × 105 CFU·g−1) near M. truncatula and a higher concentration of B. diazoefficiens (1.5-1.6 × 105 CFU·g−1) near G. max (71-82 and 15-18 nodules, respectively). Metabolomics revealed host-specific flavonoids in hyphal exudates: M. truncatula-connected hyphae released DL-liquiritigenin, naringenin, sakuranetin, and 3,7-dimethylquercetin, whereas G. max-connected hyphae released daidzin, 6”-O-malonyldaidzin, irilone, and erylatissin A. These findings establish that common mycorrhizal networks constitute a “navigation system”, using chemical signals to orient rhizobia towards their specific hosts, thereby improving nodulation with potential applications in agriculture.

Wow... Mycorrhizal fungal highways for plant signals and rhizobia  -> Legume-specific recruitment of rhizobia by hyphae of arbuscular mycorrhizal fungi | The ISME Journal | Oxford Academic

28.05.2025 18:33 — 👍 14    🔁 7    💬 0    📌 1
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The Increased Environmental Niche of Dual‐Mycorrhizal Woody Species Abiotic factors influence the global distribution of mycorrhizal host plants (ectomycorrhizal fungi and arbuscular mycorrhizal fungi), raising the possibility that dual associations with both mycorrh...

New paper! The Increased Environmental Niche of Dual‐Mycorrhizal Woody Species. Ecology Letters: onlinelibrary.wiley.com/doi/10.1111/...

Dual-host woody species occupy a broader geographical range and environmental niche space compared to those associating exclusively with either AM or EM.

22.05.2025 16:36 — 👍 11    🔁 6    💬 1    📌 0

It is sad that even basic research needs to be defended with utility. For me, basic research is in the same category as art: civilized societies can't do without it, because we all want to know who we are and what our place in the natural world is -- questions that only science can answer.

09.05.2025 21:09 — 👍 161    🔁 61    💬 7    📌 3
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Webinar Alert🌱
Want to learn cutting-edge studies in plant-microbe interaction? Join our webinar "Advances in Plant-Microbe Interactions: Insights from Asia to the World" with
@elifecommunity.bsky.social !
📅 May 19, 2025 | 🕝 JST 14:30–17:20 (UTC+9)
📌Register: u-tokyo-ac-jp.zoom.us/webinar/regi...

07.05.2025 02:30 — 👍 16    🔁 13    💬 1    📌 1

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