@gtsnexp.bsky.social
Erkennen was die Welt Im Innersten zusammenhält.
Work by Morgan Chevalier, Firas Fadel, Timea Majer, Daniel Magda, Ferenc Kilin, Lili Gerendás, and in collaboration with the labs of Zoltan Z Nagy, Szabo Arnold, and Botond Roska.
30.08.2025 08:42 — 👍 0 🔁 0 💬 0 📌 0#ProteinEngineering #TRPChannels #SyntheticBiology #VisionRestoration #Retina #GeneTherapy
30.08.2025 08:34 — 👍 0 🔁 0 💬 1 📌 0tl;dr: We trimmed human TRPV1 so it wakes up at ~41°C. Brief near‑IR “warm‑pulses” made ganglion cells in blind human retina explants fire graded spikes—no opsins, no nanoparticles, just AAV + human protein. Early‑stage, clean thermal control.
30.08.2025 08:34 — 👍 0 🔁 0 💬 0 📌 0
Just published:Engineering infrared light detection in blind human retina using ultrasensitive human TRPV1 channels.
www.sciencedirect.com/science/arti...
unobtanium
27.02.2025 12:17 — 👍 0 🔁 0 💬 0 📌 0
Hello Blue Sky, our first preprint on vision restoration is online:
www.biorxiv.org/content/10.1...
