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Simon Bullock

@simonbullock11.bsky.social

Molecular motors, mRNA localisation, microscopes4schools, MRC-LMB (Cambridge, UK)

1,364 Followers  |  422 Following  |  10 Posts  |  Joined: 12.08.2024
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Posts by Simon Bullock (@simonbullock11.bsky.social)

Research Support Officer - Cell Biology - Dr Madeline Lancaster - LMB 2788 - Medical Research Council Location: Cambridge. Vacancy: Research Support Officer - Cell Biology - Dr Madeline Lancaster - LMB 2788. Closing Date: 25/03/2026, 23:55

πŸ“£πŸ§  We're looking for someone to join the Lancaster Lab family as a Research Support Officer (maternity cover).

You'll be studying the origins of human brain specialisations using brain organoids, as part of a great team at one of the world's great research environments.

mrc.tal.net/vx/mobile-0/...

03.03.2026 13:52 β€” πŸ‘ 0    πŸ” 2    πŸ’¬ 0    πŸ“Œ 0

Join us in beautiful Portugal for the best & most comprehensive meeting on RNA localization and local translation! > 30 talks will be selected from abstracts. Held for over 30 years, this meeting is small enough to meet leaders in the field, yet big enough to cover a breadth of cutting-edge science.

03.03.2026 14:03 β€” πŸ‘ 3    πŸ” 3    πŸ’¬ 1    πŸ“Œ 0

Do you work on DNA or RNA protein complexes? 🧬

Come to Machines on Genes this June in Crete! β˜€οΈ

Super early discount is ending this Sunday so register now! πŸ˜ƒ

02.03.2026 22:08 β€” πŸ‘ 12    πŸ” 6    πŸ’¬ 0    πŸ“Œ 0

Join us!

02.03.2026 18:16 β€” πŸ‘ 15    πŸ” 6    πŸ’¬ 1    πŸ“Œ 0

Come and join us. It's such a great place to work.

02.03.2026 10:41 β€” πŸ‘ 19    πŸ” 14    πŸ’¬ 2    πŸ“Œ 0
2026 Cytoskeletal Motors Conference GRC The 2026 Gordon Research Conference on Cytoskeletal Motors will be held in Portland, Maine. Apply today to reserve your spot.

Cytoskeleton enthusiasts: join us for the Cytoskeletal Motors GRC, July 12-17, 2026, in Portland Maine. Abstracts submitted by April 5 will be considered for short talks. Please apply!
bit.ly/4cWxvzj

02.03.2026 02:52 β€” πŸ‘ 9    πŸ” 7    πŸ’¬ 0    πŸ“Œ 0
An intrinsically disordered region mediates RNA-binding selectivity and cellular activities of LARP6 - Nature Communications LARP6 is an EMT-associated RNA-binding protein with diverse RNA targets. Here, the authors show that the N-terminal disordered region of LARP6 promotes RNA-binding selectivity by modulating the adjace...

πŸŽ‰Proud to present our latest paper, out now in Nature Communications: www.nature.com/articles/s41...

RNA Binding Proteins (RBPs) are often full of intrinsically disordered regions (IDRs), but what these regions do during RNA recognition is often unclear. 1/10
#RNA #IDR #RBP

21.02.2026 23:31 β€” πŸ‘ 74    πŸ” 33    πŸ’¬ 1    πŸ“Œ 4

We are excited to be recruiting a new tenure track group leader in the Structural Studies Division at MRC LMB! It is an amazing place to start your own lab.
@mrclmb.bsky.social

Please get in touch if you have any questions.
www.nature.com/naturecareer...

25.02.2026 22:25 β€” πŸ‘ 49    πŸ” 52    πŸ’¬ 1    πŸ“Œ 0

thanks @lucksmith.bsky.social
15 years after your key paper with Nelson Lau showing the abundance & widespread nature of piRNAs from 3' UTRs, we now start to get the logic.

dissecting how the Yb protein reads out U-content, and talks to the Upf1-related SF2 helicase Armitage, will be interesting.

18.02.2026 07:30 β€” πŸ‘ 20    πŸ” 5    πŸ’¬ 1    πŸ“Œ 0
Figure showing transport dynamics of LAMP1- and LAMP2A-positive organelles.

Figure showing transport dynamics of LAMP1- and LAMP2A-positive organelles.

Reem Abouward, Giampietro Schiavo & team find that LAMP1 and LAMP2A localise to distinct axonal organelles with differential transport dynamics, but share overlapping total protein compositions.
Highlight: journals.biologists.com/jcs/article/...
Article: journals.biologists.com/jcs/article/...

17.02.2026 10:31 β€” πŸ‘ 14    πŸ” 7    πŸ’¬ 1    πŸ“Œ 0
Research Group Leader Tenure Track - Structural Studies - LMB 2775 - Medical Research Council Location: Cambridge. Vacancy: Research Group Leader Tenure Track - Structural Studies - LMB 2775. Closing Date: 16/03/2026, 23:55

Please spread the word: the Structural Studies Division @mrclmb.bsky.social is looking for a new tenure-track, independent group leader with an exciting plan in any area of Structural (Molecular & Cell) biology, in discovery biology and/or methods development. πŸ₯³

mrc.tal.net/vx/mobile-0/...

16.02.2026 12:09 β€” πŸ‘ 83    πŸ” 102    πŸ’¬ 1    πŸ“Œ 2
addison-wheeler-fellowship - Durham University

🚨 Postdoc opportunity to study memory or nutrition in #Drosophila πŸͺ°

I am looking for a candidate to support for a 3 year Addison Wheeler Fellowship application lnkd.in/e2rvNf5x

Interested? Please send a CV & cover letter with brief research outline by 20th February to vincent.croset@durham.ac.uk

12.02.2026 15:31 β€” πŸ‘ 14    πŸ” 21    πŸ’¬ 0    πŸ“Œ 1
Preview
Live-cell single-vRNP imaging identifies viral gene expression signatures that shape influenza infection heterogeneity In this study, an imaging technology, β€œVISUN,” is developed that allows live-cell visualization of unmodified influenza virus during infection with single-vRNP resolution. Combining VISUN with multipl...

Out now in Cell Systems: We develop a technique to visualize influenza A virus in live cells with single viral RNA resolution. Combined with precise readouts of viral transcription, we map the whole influenza A viral life cycle and identify key bottlenecks in infection.

www.cell.com/cell-systems...

12.02.2026 07:45 β€” πŸ‘ 42    πŸ” 9    πŸ’¬ 1    πŸ“Œ 1

Thanks @michaelboutros.bsky.social and @crisprflydesign.bsky.social for sharing! πŸ§ͺπŸ§¬βœ‚οΈπŸ”¬πŸͺ°
Multiplexed Cas12a editing plasmids here: www.addgene.org/browse/artic...

10.02.2026 17:43 β€” πŸ‘ 8    πŸ” 2    πŸ’¬ 0    πŸ“Œ 0

One week left to apply for the postdoc position at MRC-LMB in Cambridge. Join our team for an exciting project on transcription-coupled splicing to understand human gene regulation 🧬 Feel free to get in touch directly
#postdoc #cryoEM #biochemistry

05.02.2026 12:05 β€” πŸ‘ 8    πŸ” 8    πŸ’¬ 0    πŸ“Œ 0
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Searching for a human neural cell line with greater differentiation potential than SH-SY5Y cells? Check out the human #neural #stem_cell line HNSC.100. Differentiates into astrocytes, neurons & oligodendrocytes. On #BioRxiv, we provide protocols, markers, ABs, karyotyping & RNAseq: shorturl.at/y0aJG

09.02.2026 14:10 β€” πŸ‘ 4    πŸ” 1    πŸ’¬ 1    πŸ“Œ 0

Very happy to say that our work on how axonemes are generated is now available on bioRxiv: www.biorxiv.org/content/10.6... - if you’ve ever wondered how the incredibly beautiful, complex structures within motile #cilia are constructed then this is for you!

06.02.2026 11:20 β€” πŸ‘ 84    πŸ” 29    πŸ’¬ 8    πŸ“Œ 3
Postdoctoral Fellow - Cellular signalling and cytoskeletal function lab

Postdoc job alert in the Crick Institute in London. Are you interested in the actin cytoskeleton? I am looking for a postdoc to examine the cellular, developmental or physiological role of Arp2/3 iso-complex driven actin polymerisation. Multiple aspects available.
crick.ac.uk/WayPostdoc2026

06.02.2026 08:23 β€” πŸ‘ 26    πŸ” 29    πŸ’¬ 0    πŸ“Œ 4
Postdoctoral Fellow - Cellular signalling and cytoskeletal function lab

2nd postdoc job alert in the Crick Institute in London. Project will examine the role of motors & the cytoskeleton (actin, septins and microtubules) during vaccinia virus egress using biochemical, structural & cellular approaches + live cell imaging. spread the word.
crick.ac.uk/WayPostdoc20...

06.02.2026 08:29 β€” πŸ‘ 30    πŸ” 40    πŸ’¬ 0    πŸ“Œ 1

The registration deadline for this wonderful meeting is approaching! Be sure to reserve your spot before March 10!

04.02.2026 18:10 β€” πŸ‘ 10    πŸ” 8    πŸ’¬ 0    πŸ“Œ 0

This is for you – and a great opportunity – if you are establishing a group in Croatia, Czechia, Estonia, Hungary, Lithuania, Luxembourg, Poland, Portugal and TΓΌrkiye...

04.02.2026 08:42 β€” πŸ‘ 6    πŸ” 8    πŸ’¬ 0    πŸ“Œ 0
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Job alert! πŸ“£ I’m looking for a research assistant to join my new team @idrm.ox.ac.uk

Were using #zebrafish to understand gene-environment interactions that shape the heart πŸ«€generate natural diversity 🐸🐭 and contribute to congenital defects β€οΈβ€πŸ©Ή

Full info below, and please share! 🫢🏻

bit.ly/467TO0M

02.02.2026 14:01 β€” πŸ‘ 34    πŸ” 22    πŸ’¬ 0    πŸ“Œ 1
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The IGNITION PhD Programme is now open! We’re offering 13 fully funded PhD positions across 10 institutions in 8 EU countries to study immune mediated neurodegeneration.

If you're passionate about research, innovation & international collaboration, this is for you.

ignition-consortium.eu/home/

02.02.2026 09:31 β€” πŸ‘ 5    πŸ” 4    πŸ’¬ 0    πŸ“Œ 0

This is another tour de force from @crisprflydesign.bsky.social and colleagues with consideration of utility for the community at its heart. Great work!

29.01.2026 16:51 β€” πŸ‘ 0    πŸ” 1    πŸ’¬ 1    πŸ“Œ 0

More efficient CRISPR targeting in Drosophila, via Cas12a and easier synthesis of multiplexed gRNAs

29.01.2026 09:49 β€” πŸ‘ 2    πŸ” 1    πŸ’¬ 0    πŸ“Œ 0
Preview
RNA-binding proteins and ribonucleoproteins as determinants of immunity - Nature Reviews Immunology RNA-binding proteins (RBPs) considerably expand the information content of the genome and can determine the lifespan, localization and function of RNA, thereby controlling when, where and how much pro...

Just out @natrevimmunol.nature.com
RNA-binding proteins and ribonucleoproteins as determinants of immunity
www.nature.com/articles/s41...
gives our perspective on this growing area of research. Special thanks to the editor Alexandra, for streamlining the manuscript.

27.01.2026 07:32 β€” πŸ‘ 38    πŸ” 21    πŸ’¬ 1    πŸ“Œ 1
Suyang Zhang smiles in front of a blurred laboratory background

Suyang Zhang smiles in front of a blurred laboratory background

Exciting opportunity for a #postdoc to join @suyangzhang.bsky.social’s group in the LMB Structural Studies Division to investigate co-transcriptional splicing using cryo-EM and biochemistry.
Read more: www.nature.com/naturecareer...
Apply by 11 FEB
#PostdocJobs #ScienceJobs

27.01.2026 09:40 β€” πŸ‘ 5    πŸ” 11    πŸ’¬ 0    πŸ“Œ 0
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I’m happy to share the main result of my PhD, which you can find on bioRxiv www.biorxiv.org/content/10.6.... If you are interested in learning about a new way to perform DNA-PAINT multiplexing, which we call Combi-PAINT, or if you are interested in the study of mRNA conformation, keep reading! 1/10

26.01.2026 11:31 β€” πŸ‘ 74    πŸ” 26    πŸ’¬ 3    πŸ“Œ 5
Winship Postdoctoral Fellow Recruitment Event

Hitting the postdoc search? Consider applying to be part of the Winship postdoc recruitment cohort @winshipcancer.emory.edu

apps.winshipcancer.emory.edu/admin/Event/...

Eligibility requirements and participating faculty are listed in the linkβœ…

26.01.2026 15:25 β€” πŸ‘ 2    πŸ” 4    πŸ’¬ 0    πŸ“Œ 0

Tom Cech on RNA research in Davos (video): www.weforum.org/meetings/wor...

21.01.2026 21:24 β€” πŸ‘ 16    πŸ” 9    πŸ’¬ 0    πŸ“Œ 1