ASHE Journal

An outpatient antimicrobial stewardship needs assessment | Antimicrobial Stewardship & Healthcare Epidemiology | Cambridge Core An outpatient antimicrobial stewardship needs assessment - Volume 5 Issue 1

Outpatient providers at a tertiary care center were surveyed regarding their antibiotic prescribing practices and views on ASP. Many clinical and non-clinical factors shape their decision-making. Electronic medical record interventions were a favored stewardship strategy. doi.org/10.1017/ash....

Severe COVID-19, advanced age, and Chronic kidney disease are linked to bacterial infections in hospitalized patients. High antibiotic use (60%) was found in COVID-19 patients without confirmed bacterial infection highlighting an urgent need for antibiotic stewardship in LMICs.

Opportunities for early oral therapy for prosthetic hip and knee joint infections (PJI): clinical experience at a large health authority | Antimicrobial Stewardship & Healthcare Epidemiology | Cambridge Core Opportunities for early oral therapy for prosthetic hip and knee joint infections (PJI): clinical experience at a large health authority - Volume 5 Issue 1

In our study, we found that about half of patients with prosthetic joint infections are candidates for early oral switch therapy. This finding provides an opportunity for quality improvement in terms of antimicrobial and resource stewardship. doi.org/10.1017/ash....

Physician knowledge, attitudes, and perceptions of antibiograms: a pre-implementation study in southern Sri Lanka | Antimicrobial Stewardship & Healthcare Epidemiology | Cambridge Core Physician knowledge, attitudes, and perceptions of antibiograms: a pre-implementation study in southern Sri Lanka - Volume 5 Issue 1

From @thesillysci.bsky.social: Our study explores Sri Lankan physicians’ knowledge, attitudes, & practices around antibiograms in a public hospital. Findings: gaps in awareness, perceived barriers to implementation, the need for context-specific education and support tools. doi.org/10.1017/ash....

Business intelligence for detecting possible surgical site infections from post-cesarean section operation with a focus on antibiotic prescriptions in Ramathibodi Hospital, Thailand doi.org/10.1017/ash....

Applying the Learning Health System framework to overcome barriers in antimicrobial decision support: lessons from the Guidance redesign | Antimicrobial Stewardship & Healthcare Epidemiology | Cambridge Core Applying the Learning Health System framework to overcome barriers in antimicrobial decision support: lessons from the Guidance redesign - Volume 5 Issue 1

Read on in this letter to the editor--Applying the Learning Health System framework to overcome barriers in antimicrobial decision support: lessons from the Guidance redesign doi.org/10.1017/ash....

Candida auris surveillance in the Military Health System: a multidrug-resistant threat | Antimicrobial Stewardship & Healthcare Epidemiology | Cambridge Core Candida auris surveillance in the Military Health System: a multidrug-resistant threat - Volume 5 Issue 1

Case series of Candida auris identified in the US Military Health System. Includes cases identified in 6 hospitals with suspected domestic US and international acquisition, genetic and antimicrobial susceptibility analysis, and a review of hospital surveillance protocols.
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Collaboration to harmonize antimicrobial registry measures (CHARM) database analysis of antibiotic prescribing in urgent and non-urgent care: a retrospective study on demographic factors doi.org/10.1017/ash....

Antifungal use and appropriateness: a study of Australian Hospital National Antimicrobial Prescribing Survey data | Antimicrobial Stewardship & Healthcare Epidemiology | Cambridge Core Antifungal use and appropriateness: a study of Australian Hospital National Antimicrobial Prescribing Survey data - Volume 5 Issue 1

National analysis of 7,830 systemic antifungal prescriptions across 372 Australian hospitals (2014-24) found 88.4% guideline compliance, 92.3% appropriateness. Stewardship approval improved quality. Fluconazole showed lower appropriateness, highlighting areas for improvement.
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A quasi-experimental study in a tertiary hospital assessed an indication-based electronic prescribing intervention for meropenem. Use declined by 41.14% without compromising appropriate treatment, supporting its effectiveness in antimicrobial stewardship. doi.org/10.1017/ash....

Measuring the disinfection efficacy of the Tru-D iQ and Tru-D Legacy systems in acute patient care hospital rooms: a randomized experimental study | Antimicrobial Stewardship & Healthcare Epidemiology | Cambridge Core Measuring the disinfection efficacy of the Tru-D iQ and Tru-D Legacy systems in acute patient care hospital rooms: a randomized experimental study - Volume 5 Issue 1

In this randomized experimental study, Tru-D iQ and Legacy UV-C systems both reduced environmental contamination in hospital rooms. Both systems significantly reduced contamination, with the Tru-D iQ achieving comparable efficacy overall and significantly shorter cycle times. doi.org/10.1017/ash....

Impact of multifaceted clinical decision support and education on antibiotic duration in outpatients with respiratory tract infections in Saudi Arabia: a prospective pre- and postimplementation study | Antimicrobial Stewardship & Healthcare Epidemiology | Cambridge Core Impact of multifaceted clinical decision support and education on antibiotic duration in outpatients with respiratory tract infections in Saudi Arabia: a prospective pre- and postimplementation study…

Impact of multifaceted clinical decision support and education on antibiotic duration in outpatients with respiratory tract infections in Saudi Arabia: a prospective pre- and postimplementation study doi.org/10.1017/ash....

The fault in our SAAR: optimization and implementation of health-system dashboards for antimicrobial use and SAAR data | Antimicrobial Stewardship & Healthcare Epidemiology | Cambridge Core The fault in our SAAR: optimization and implementation of health-system dashboards for antimicrobial use and SAAR data - Volume 5 Issue 1

This healthcare system integrated SAAR data into their ASP customizing their EHR's tools. A dynamic dashboard for SAAR and AU data + a new SOP for SAAR analyssis = a game changer for ASPs! doi.org/10.1017/ash....

@brxad.bsky.social et al: Is AMR a topic confined to our small echo chamber? Here are 4 strategies to help engage the other 99.9% in the conversation about AMR (happy #WAAW week!) doi.org/10.1017/ash....

Candidiasis epidemiology and outcomes including emergence of Candida auris from a large, Southern US metro area: a six-year evaluation | Antimicrobial Stewardship & Healthcare Epidemiology | Cambridge Core Candidiasis epidemiology and outcomes including emergence of Candida auris from a large, Southern US metro area: a six-year evaluation - Volume 5 Issue 1

Candidiasis epidemiology and outcomes including emergence of Candida auris from a large, Southern US metro area: a six-year evaluation doi.org/10.1017/ash....

Temporal trends of inpatient oral penicillin challenges in a U.S. veteran cohort with a recorded penicillin allergy | Antimicrobial Stewardship & Healthcare Epidemiology | Cambridge Core Temporal trends of inpatient oral penicillin challenges in a U.S. veteran cohort with a recorded penicillin allergy - Volume 5 Issue 1

In an analysis of a U.S. veteran cohort with a listed penicillin allergy, we demonstrated both a temporal rise in the numbers of oral penicillin challenges performed and facilities involved in performing such challenges from 2014 to 2024. doi.org/10.1017/ash....

It’s QuizTime! The impact of web-based microlearning quizzes on guideline-concordant antibiotic duration for pediatric acute otitis media | Antimicrobial Stewardship & Healthcare Epidemiology | Cambridge Core It’s QuizTime! The impact of web-based microlearning quizzes on guideline-concordant antibiotic duration for pediatric acute otitis media - Volume 5 Issue 1

New study shows that repeated micro-learning quizzes improve guideline-concordant antibiotic prescribing for pediatric acute otitis media. QuizTime may be an effective, scalable, and low-effort way to deliver antimicrobial education to busy prescribers! doi.org/10.1017/ash....

Mandatory linking of penicillin allergy “safety alert” with beta-lactam medication history: correcting the automated inaccuracy of penicillin allergy labeling and beta-lactam antibiotic avoidance | Antimicrobial Stewardship & Healthcare Epidemiology | Cambridge Core Mandatory linking of penicillin allergy “safety alert” with beta-lactam medication history: correcting the automated inaccuracy of penicillin allergy labeling and beta-lactam antibiotic avoidance...

We present a durable, novel EHR intervention whose implementation can help decrease the pervasive harmful beta-lactam antibiotic avoidance behavior due to clinically inaccurate penicillin allergy alerts. doi.org/10.1017/ash....

Early de-escalation of empiric antibiotic therapy in neutropenic fever: a single-center, retrospective study | Antimicrobial Stewardship & Healthcare Epidemiology | Cambridge Core Early de-escalation of empiric antibiotic therapy in neutropenic fever: a single-center, retrospective study - Volume 5 Issue 1

Early de-escalation of empiric antibiotics in neutropenic fever at our urban medical center significantly reduced duration of therapy without increasing subsequent infections, clinical decompensation, or in-hospital mortality, supporting the safety of this approach. doi.org/10.1017/ash....

A review of nasal MRSA PCR screening practices across 9 institutions in Kentucky found most used it for pneumonia indications. None permitted pharmacists to discontinue anti-MRSA antibiotics per protocol, highlighting a stewardship gap. doi.org/10.1017/ash....

A research agenda for burn infection prevention: identifying knowledge gaps and prioritizing future directions | Antimicrobial Stewardship & Healthcare Epidemiology | Cambridge Core A research agenda for burn infection prevention: identifying knowledge gaps and prioritizing future directions - Volume 5 Issue 1

Patients with burn injuries are particularly susceptible to HAIs due to the loss of skin barrier and altered immune responses. Presented here is a research agenda that identifies key gaps and priorities for future investigation in this high-risk population. doi.org/10.1017/ash....

Retrospective cohort study of the microbiology and clinical outcomes of spontaneous bacterial peritonitis (SBP) within a US academic health system | Antimicrobial Stewardship & Healthcare Epidemiology | Cambridge Core Retrospective cohort study of the microbiology and clinical outcomes of spontaneous bacterial peritonitis (SBP) within a US academic health system - Volume 5 Issue 1

Within an academic health system, patients with spontaneous bacterial peritonitis who received empiric third-generation cephalosporin monotherapy had similar clinical outcomes as those who received empiric broad spectrum therapy, including similar 30 and 90-day mortality. doi.org/10.1017/ash....

@dvilarc.bsky.social: we review the introduction of gloves into medicine, their recommended use, and the issues of contamination and misuse. The final section examines the environmental impact of gloves and offers strategies to reduce glove-related contamination. doi.org/10.1017/ash....

Dynamics of respiratory virus spread indoors suggest a holistic approach for exposure risk mitigation | Antimicrobial Stewardship & Healthcare Epidemiology | Cambridge Core Dynamics of respiratory virus spread indoors suggest a holistic approach for exposure risk mitigation - Volume 5 Issue 1

Read on for holistic consideration of the importance of all transmission pathways and the corresponding need for targeted NPIs during virus outbreaks and pandemics: doi.org/10.1017/ash....

Evaluation of outpatient clindamycin prescriptions across a large military healthcare network | Antimicrobial Stewardship & Healthcare Epidemiology | Cambridge Core Evaluation of outpatient clindamycin prescriptions across a large military healthcare network - Volume 5 Issue 1

One year of outpatient clindamycin prescriptions at a military healthcare system demonstrated that less than half of patients had a beta-lactam allergy and that the top 2% of prescribers accounted for 18% of prescriptions. doi.org/10.1017/ash....

Efficacy of swish and gargle and other collection methods with the use of Abbott ID NOW in COVID-19 detection | Antimicrobial Stewardship & Healthcare Epidemiology | Cambridge Core Efficacy of swish and gargle and other collection methods with the use of Abbott ID NOW in COVID-19 detection - Volume 5 Issue 1

Diagnosing covid by "swish and gargle" method--read on! doi.org/10.1017/ash....

Implementation of a hospital-wide EHR-integrated antibiotic challenge order set | Antimicrobial Stewardship & Healthcare Epidemiology | Cambridge Core Implementation of a hospital-wide EHR-integrated antibiotic challenge order set - Volume 5 Issue 1

We implemented an EHR-integrated order set to standardize direct abx challenges. In the first year, 104 patients were challenged (79% oral; 39% two-step). Embedded antibiotic selection, dosage, monitoring parameters, and rescue medications facilitated uptake by clinicians. doi.org/10.1017/ash....

Predictors of antibiotic prescription for upper respiratory infections in cancer patients | Antimicrobial Stewardship & Healthcare Epidemiology | Cambridge Core Predictors of antibiotic prescription for upper respiratory infections in cancer patients - Volume 5 Issue 1

Almost one-third of ambulatory cancer patients were prescribed antibiotics for acute upper respiratory infections. Negative respiratory pathogen panel results or a negative influenza result were two predictors for antibiotic prescribing. doi.org/10.1017/ash....

Beyond the bugs: why toxin detection is key in two-tiered C. diff tests | Antimicrobial Stewardship & Healthcare Epidemiology | Cambridge Core Beyond the bugs: why toxin detection is key in two-tiered C. diff tests - Volume 5 Issue 1

Beyond the bugs: why toxin detection is key in two-tiered C. diff tests doi.org/10.1017/ash....

Antimicrobial changes made for suspected infectious diarrhea after positive gastrointestinal pathogen panel result | Antimicrobial Stewardship & Healthcare Epidemiology | Cambridge Core Antimicrobial changes made for suspected infectious diarrhea after positive gastrointestinal pathogen panel result - Volume 5 Issue 1

In a retrospective study of positive multiplex molecular gastrointestinal pathogen tests sent for evaluation of infectious diarrhea, approximately one-third were associated with a change in antimicrobial treatment. Most of these changes were consistent with IDSA guidelines. doi.org/10.1017/ash....