Abhishek Garg LAB

👏Looking frwd to talk: #Multiomics #spatial context in #Cancer: from #immunobiology to next-gen #therapies @myesmo.bsky.social (cslide.ctimeetingtech.com/coasis_21467...)
🔥Will reveal best-in-class #trispecific #macrophage #activator #antibody capable of >90% inhibition of #immunoresistant #tumours

Molecular analysis and immunological characterization of a founder mutation causing ARPC1B deficiency - Genes & Immunity Genes & Immunity - Molecular analysis and immunological characterization of a founder mutation causing ARPC1B deficiency

🚨 #Research #alert

#Molecular analysis and #immunological characterization of a #founder #mutation causing #ARPC1B #deficiency

#Genes & #Immunity @springernature.com
www.nature.com/articles/s41...

Spatiotemporal transcriptomic insights into ferroptosis and TFRC-linked immune interactions in ischemia-reperfusion acute kidney injury - Genes & Immunity Genes & Immunity - Spatiotemporal transcriptomic insights into ferroptosis and TFRC-linked immune interactions in ischemia-reperfusion acute kidney injury

💥 #Cool #Research #Alert

#Spatiotemporal #transcriptomic insights into #ferroptosis and TFRC-linked #immune #interactions in #ischemia-#reperfusion acute #kidney #injury

#Genes & #Immunity @springernature.com
www.nature.com/articles/s41...

Macrophage retrotransposon expression is associated with lupus - Genes & Immunity Genes & Immunity - Macrophage retrotransposon expression is associated with lupus

💥👁 #Exciting #research #alert
#Macrophage #retrotransposon expression is associated with #lupus

#genes & #Immunity @springernature.com
www.nature.com/articles/s41...

YTHDF1 mediates KLF2/VSIG4 axis to regulate Kupffer cell polarization to alleviate sepsis-induced liver injury - Genes & Immunity Genes & Immunity - YTHDF1 mediates KLF2/VSIG4 axis to regulate Kupffer cell polarization to alleviate sepsis-induced liver injury

💥 #YTHDF1 mediates #KLF2/ #VSIG4 axis to regulate #Kupffer #cell #polarization to alleviate #sepsis-induced #liver #injury

#genes & #Immunity @springernature.com
www.nature.com/articles/s41...

Effects of nucleic acid metabolism on prognosis and immune invasion of triple-negative breast cancer - Genes & Immunity Genes & Immunity - Effects of nucleic acid metabolism on prognosis and immune invasion of triple-negative breast cancer

🚨 Effects of #nucleic #acid #metabolism on #prognosis and #immune #invasion of triple-negative #breast #cancer

#genes & #Immunity @springernature.com www.nature.com/articles/s41...

Hspa8 modulation of immune responses mitigates ischemic brain injury - Genes & Immunity Genes & Immunity - Hspa8 modulation of immune responses mitigates ischemic brain injury

🚨 #Research #alert
#Hspa8 modulation of #immune #responses mitigates #ischemic #brain #injury

#Genes & #Immunity @springernature.com
www.nature.com/articles/s41...

Taxonomic variation in immune response strategies among primates - Genes & Immunity Genes & Immunity - Taxonomic variation in immune response strategies among primates

🔥 #Review #alert
#Taxonomic #variation in #immune #response strategies among #primates

#Genes & #immunity @springernature.com
www.nature.com/articles/s41...

Computational neoantigen prediction for cancer immunotherapy - Genes & Immunity Genes & Immunity - Computational neoantigen prediction for cancer immunotherapy

🔥 #Review #alert
#Computational #neoantigen #prediction for #cancer #immunotherapy

#Genes & #immunity @springernature.com
www.nature.com/articles/s41...

⏰#October issue of #Genes & #Immunity is online!
👉Read abt #autism, #viral #infection, #inflammatory #bowel #disease #IBD, #Alzheimer #disease, #interferon #responses, #colorectal #cancer, #periodontitis, #microRNA, #lupus, #thymocyte & #celiac #disease
www.nature.com/gene/volumes...

Abnormal activation of platelets and inflammation in smoking-induced rheumatoid arthritis is alleviated by 3,3′-diindolylmethane - Genes & Immunity Genes & Immunity - Abnormal activation of platelets and inflammation in smoking-induced rheumatoid arthritis is alleviated by 3,3′-diindolylmethane

#Abnormal #activation of #platelets and #inflammation in #smoking-induced #rheumatoid #arthritis is alleviated by 3,3′-diindolylmethane

#Genes & #immunity @springernature.com
www.nature.com/articles/s41...

Post-translational acylation modulates immunosuppression and immunotherapy efficacy in hepatocellular carcinoma - Genes & Immunity Genes & Immunity - Post-translational acylation modulates immunosuppression and immunotherapy efficacy in hepatocellular carcinoma

Post-translational #acylation modulates #immunosuppression and #immunotherapy #efficacy in #hepatocellular #carcinoma
#livercancer
#Genes & #immunity @springernature.com
www.nature.com/articles/s41...

αCGRP deficiency aggravates pulmonary fibrosis by promoting senescence in alveolar type 2 cells - Genes & Immunity Genes & Immunity - αCGRP deficiency aggravates pulmonary fibrosis by promoting senescence in alveolar type 2 cells

αCGRP deficiency aggravates #pulmonary #fibrosis by promoting #senescence in #alveolar type 2 #cells

#Genes & #immunity @springernature.com
www.nature.com/articles/s41...

PhD position on Cancer Immunology & Immunotherapy PhD position on Cancer Immunology & Immunotherapy

🚨 #JOBALERT
👉We r hiring! R u interested in #cuttingedge #kidneycancer #research aiming fr #highimpact #Immunotherapy w/ real #clinical #impact fr #Kidney #cancer #patients?
🧐Then this #PhD #doctoral position is 4u
👉Apply/spread it!
@kuleuvenuniversity.bsky.social
www.kuleuven.be/personeel/jo...

The epigenomic landscape of bronchial epithelial cells reveals the establishment of trained immunity - Genes & Immunity Genes & Immunity - The epigenomic landscape of bronchial epithelial cells reveals the establishment of trained immunity

The #epigenomic #landscape of #bronchial #epithelial cells reveals the establishment of #trained #immunity

#Genes & #Immunity @springernature.com
www.nature.com/articles/s41...

Dexmedetomidine relieves LPS-induced acute lung injury by boosting HIF-1a/ACOD1 driven anti-inflammatory macrophage polarization - Genes & Immunity Genes & Immunity - Dexmedetomidine relieves LPS-induced acute lung injury by boosting HIF-1a/ACOD1 driven anti-inflammatory macrophage polarization

#Dexmedetomidine relieves #LPS-induced #acute #lung #injury by boosting HIF-1a/ACOD1 driven anti-#inflammatory #macrophage #polarization

#Genes & #Immunity @springernature.com
www.nature.com/articles/s41...

Neoadjuvant PD-1 and LAG-3-targeting bispecific antibody and other immune checkpoint inhibitor combinations in resectable melanoma: the randomized phase 1b/2 Morpheus-Melanoma trial - Nature Medicine In the randomized phase 1b/2 Morpheus-Melanoma trial evaluating various neoadjuvant immune checkpoint inhibitor regimens in patients with resectable stage III melanoma, tobemstomig, an anti-PD-1/anti-LAG-3 bispecific antibody, showed the highest pathologic response rate with a better safety profile than the standard treatment approach of ipilimumab plus nivolumab.

💪#Power of #bispecifics in #cancer #patient #treatment?
✴️Anti-#PD1 x #LAG3 #bispecific had similar anti-#tumour #efficacy vs anti-#PD1/anti-#CTLA4 #combo but with better #safety #profile
⏲️Time to move #multispecifics vs #macrophages where #monos failed!
www.nature.com/articles/s41...

@natrevimmunol.nature.com
rdcu.be/eGXJH

TUG1 targeting enhances anticancer immunity thereby facilitating lenvatinib efficacy in hepatocellular carcinoma - Genes & Immunity Genes & Immunity - TUG1 targeting enhances anticancer immunity thereby facilitating lenvatinib efficacy in hepatocellular carcinoma

#TUG1 targeting enhances #anticancer #immunity thereby facilitating #lenvatinib efficacy in #hepatocellular #carcinoma

#Genes & #Immunity @springernature.com
www.nature.com/articles/s41...

Transcriptomics and eQTLs reveal inflammatory heterogeneity in the duodenal lining in coeliac disease - Genes & Immunity Genes & Immunity - Transcriptomics and eQTLs reveal inflammatory heterogeneity in the duodenal lining in coeliac disease

#Transcriptomics and #eQTLs reveal #inflammatory #heterogeneity in the #duodenal lining in #coeliac #disease

#Genes & #immunity @springernature.com
www.nature.com/articles/s41...

Transcriptional regulation of Ligase IV by an intronic regulatory element directs thymocyte development - Genes & Immunity Genes & Immunity - Transcriptional regulation of Ligase IV by an intronic regulatory element directs thymocyte development

#Transcriptional #regulation of #Ligase IV by an #intronic #regulatory #element directs #thymocyte #development

#Genes & #Immunity @springernature.com
www.nature.com/articles/s41...

Discovery of core genes for systemic lupus erythematosus via genome-wide aggregated trans-effects analysis - Genes & Immunity Genes & Immunity - Discovery of core genes for systemic lupus erythematosus via genome-wide aggregated trans-effects analysis

#Discovery of #core #genes for #systemic #lupus #erythematosus via #genome-wide aggregated #trans-#effects #analysis

#Genes & #Immunity @springernature.com
www.nature.com/articles/s41...

IRF3 in viral infections: more than just triggering the interferon response - Genes & Immunity Genes & Immunity - IRF3 in viral infections: more than just triggering the interferon response

#IRF3 in #viral #infections: more than just triggering the #interferon #response

#Genes & #immunity @springernature.com
www.nature.com/articles/s41...

IRF3 in viral infections: more than just triggering the interferon response - Genes & Immunity Genes & Immunity - IRF3 in viral infections: more than just triggering the interferon response

IRF3 in viral infections: more than just triggering the interferon response

www.nature.com/articles/s41...

Full access to the article is possible here:
links.springernature.com/f/a/s-eVfDXD...

📌In #September @natrevimmunol.nature.com issue, read our #comprehensive #Review: "The #Diversity of #CD8+ T #cell #dysfunction in #cancer and #viral #infection"

⏩Read: www.nature.com/articles/s41...

🤝Result of fruitful #Collaboration w/ @deadoc80.bsky.social @labliston.bsky.social & Kellie Smith!

🙏😇🙏

An efficient framework to decipher microRNA regulatory programs applied to T cells - Genes & Immunity Genes & Immunity - An efficient framework to decipher microRNA regulatory programs applied to T cells

An #efficient #framework to decipher #microRNA #regulatory #programs applied to #Tcells

#Genes & #Immunity @springernature.com
www.nature.com/articles/s41...

🚨#August #Genes & #Immunity is out: www.nature.com/gene/volumes...
⏩READ ABT: #metabolism #CD4 #Tcells #NKcells #colorectal #cancer, #nonalcoholic #steatohepatitis, #breastcancer #macrophages, #Immunology #kidneycancer #uveal #melanoma #fulminant #myocarditis; #pyroptosis #arthritis!

Academic language has become a proxy for European culture wars Some European governments are rethinking the use of English in universities, exposing tensions between internationalization and national priorities.

👍2 decades ago, #European #universities were racing to #internationalize
🧐Today, that #consensus has fractured
😓#European #governments are rethinking use of #English in universities, exposing tensions between internationalization & national priorities!
www.nature.com/articles/d41...