Marcus Kaiser

You need to be registered healthcare practitioner in the UK. If so, you can contact the programme manager Roxanne for the application form. The deadline is this Tuesday.

Are you a registered healthcare professional searching for a PhD position?

Using Zenbud #ultrasound #vagusnerve stimulation, the PhD position with me and Ben Marson is about 'Reducing pain reactivity for children in Emergency Departments'

midlandsmhndtp.ac.uk/uon-students...

We attended the London Great Exhibition Road festival over the weekend and 250+ people tried our Zenbud vagus nerve stimulation device!

One person suffering from anxiety/depression even came back on day 2 bringing a friend...

www.zenbud.health

#ultrasound #neuromodulation #vagusnerve
#ExRdFest

Our N3 Centre for Neurotechnology, Neuromodulation, and Neurotherapeutics has officially launched at @uniofnottingham.bsky.social

#neuromodulation #imaging #focusedultrasound @fusfoundation.bsky.social

www.nottingham.ac.uk/news/centre-...

30 April deadline approaching!

Last chance to apply...

Last chance to apply! Deadline: Monday 7 April...

Nice comparison of ultrasound and temporal interference stimulation in Table 3:
www.mrcbndu.ox.ac.uk/sites/defaul...

Ultrasound blinding option that is not mentioned is ventricle stimulation: doi.org/10.1016/j.br...

Join our lab for a year with the 'AI for Precision Neuromodulation' fellowship project!

Find out more at: encode.pillar.vc/projects/neu...

YouTube video by Brainbox Ltd Changing Connectomes: Improved Cognition Through Focused Ultrasound Neuromodulation

My Brainbox webinar talk that I gave yesterday on Focused Ultrasound Neuromodulation is now online:
www.youtube.com/watch?v=vJ3E...

@brainbox-neuro.bsky.social

Postdoctoral fellowship on developing human closed-loop noninvasive ultrasound and magnetic stimulation is now available!

Find out more and apply here:
jobs.nottingham.ac.uk/Vacancy.aspx...

In conclusion, our investigation in a high-powered awake non-human primate dataset shows that some FUS effects across the network last for an hour, maybe longer.

This approach could be translated to humans by using several acquisitions per subject or longer sequences.
doi.org/10.1016/j.cr...

5/5

Conversely, brain metrics related to activity (fALFF) and signal homogeneity (ReHo) are altered for much longer: Going outside our time window of 100 minutes.

doi.org/10.1016/j.cr...

4/5

We demonstrated that brain connectivity between the target and the rest of the brain was mostly changed for around 1h following the ultrasound
stimulation.

doi.org/10.1016/j.cr...

3/5

In this article, we present results about one animal who underwent around 50 MRIs, half of which followed ultrasound stimulation of the left anterior part of the hippocampus, a promising target since it is involved in so many brain dysfunctions.

doi.org/10.1016/j.cr...

2/5

I am very happy to share our latest work, led by C. Atkinson-Clement, C. Petkov, and M. Kaiser, on the temporal dynamics of brain changes following ultrasound stimulation in the rhesus monkey.

A huge thanks to all the team for making this work possible.

doi.org/10.1016/j.cr...

1/5

short video summary here: www.youtube.com/watch?v=-aeD...

Would recording all neurons reveal their interactions? For years, I was captivated by the idea that if we could record the activity of every neuron in the brain, we’d eventually crack the code…

If we could record all neurons we still would not know how they communicate: medium.com/@kording/628...

Our press release about the results is now online here:
www.nottingham.ac.uk/news/patient...

We are soon starting our 5-year MRC programme grant on novel noninvasive ultrasound or magnetic stimulation for brain and mental health (see press release below).

Watch out for our job advertisement for a postdoctoral fellow in neuromodulation later on...

www.nottingham.ac.uk/news/new-res...

A chance to join our Centre for Neurotechnology, Neuromodulation, and Neurotherapeutics by applying for a Newton postdoctoral fellowship from the Royal Society.

If you are interested in 11.7T human MRI, OPM-MEG, noninvasive neuromodulation (e.g. focused ultrasound), or mental health let us know...

Our survey article on how public and patients perceive interventions for brain and mental health, from implants and drugs to noninvasive focused ultrasound, is now published!

doi.org/10.1038/s415...

@fusfoundation.bsky.social @itrusst.bsky.social @brainbox-neuro.bsky.social

PhD position available for healthcare professionals on 'Mechanisms of action of ultrasound vagus nerve stimulation in generalised anxiety disorder'

midlandsmhndtp.ac.uk/project/2025...

Looks like I found the xmas tree option ;->

This Medical Device Went to Market... And the rest languished. A brief history.

Why do we have so many medical drugs and so few medical devices in outpatient mental health? And explanation.

open.substack.com/pub/thefront...

How measurement noise limits the accuracy of brain-behaviour predictions - Nature Communications Our ability to identify associations between behaviour and brain imaging is important for uncovering markers of cognition and disease. Here, the authors illustrate the importance of the reliability of...

The limiting factor for MRI based prediction of behavioral traits may be neither the imaging nor the pipeline or learning algorith but rather the reliability of the target phenotypes

Thought provoking work my Martin Gell et al:

www.nature.com/articles/s41...

A simulated annealing algorithm for randomizing weighted networks - Nature Computational Science This study proposes an algorithm for generating randomized networks that preserve the weighted degree sequence. The procedure outperforms standard rewiring algorithms and extends to multiple network t...

New paper in press! A simulated annealing algorithm for randomizing weighted networks | www.nature.com/articles/s43...

Yes, I saw that paper. Important to keep in mind that this was a test in M1. From other stimulation approaches we know that effects might differ between brain regions. In the same way parameter sets for excitation after ultrasound stimulation could be (slightly?) different in other brain regions...

The fully formatted article is now available at doi.org/10.1016/j.br...

What parameters enhance or suppress brain function for online and offline focussed ultrasound stimulation?

Find out from our review:
'Neuromodulation with Ultrasound: Hypotheses on the Directionality of Effects and a Community Resource'

doi.org/10.7554/eLif... @elife.bsky.social

The article on ventricle ultrasound stimulation as a gold-standard control condition is now in press at Brain Stimulation.

Brilliant work led and initiated by my colleague Dr JeYoung Jung:

doi.org/10.1016/j.br...

@fusfoundation.bsky.social