Bruce Verchere

Novel insights into the molecular underpinnings of islet cell dysfunction in #T1D highlighting pathways that may be leveraged to preserve residual β-cell function and modulate α-cell activity @bcellorg.bsky.social www.jci.org/articles/vie...

New Molecules and Indications for GLP-1 Medicines This Perspective explores recent progress and future directions in glucagon-like peptide-1 medicines.

The first GLP-1 medicine, twice daily exenatide was approved April 28 2005. Several decades later, the pace of innovation is expanding rapidly, encompassing new medicines and receptors, unique delivery options, and expanding therapeutic indications jamanetwork.com/journals/jam...

Congrats Meltem, that was an outstanding PhD defense!
Good luck in your next career steps!

Congratulations and thanks to both Sarah Cs @sarahcrome.bsky.social @sarahcolpitts.bsky.social for including us as part of this lovely study, showing a role or ILC2s in islet graft survival.

How nice! Proud to be part of that group of colleagues and child health researchers. What a lovely recognition of recipients and reminder of Dr Hammond's leadership at @bcchresearch.bsky.social.

Eukaryotic translation initiation factor 2A protects pancreatic beta cells during endoplasmic reticulum stress while rescuing global translation inhibition - Diabetologia Aims/hypothesis The endoplasmic reticulum (ER) stress-induced unfolded protein response helps determine beta cell survival rate in diabetes. The alternative eukaryotic translation initiation factor 2A...

New study on novel translation factor EIF2A led by Panzhinskiy as a collaboration between @jimjohnsonsci.bsky.social lab, Jan lab & @bruceverchere.bsky.social lab UBC Life Sciences Institute. Thanks Breakthrough T1D Canada for funding this project #DiabetesResearch link.springer.com/article/10.1...

and can play anywhere!

Join Us! | King Lab Are you interested in joining the King Lab? More information here!

Come join us at beautiful UBC! The King Lab is recruiting a Post-doc Fellow to develop mathematical theory on infectious disease evolution and emergence, together with Ben Ashby (SFU) #zoonoses #biodiversity www.zoology.ubc.ca/kinglab/join...

Always enjoy this discussion of islet biology and other things like reproducibility in science with @danieljdrucker.bsky.social and fantastic @cirtn.bsky.social grad students from across Canada each year!

Thanks for hosting us!
Such great diabetes and nutrition research, wonderful people, lovely location, outstanding trainee presentations, and fun social events!

Postdoctoral Research Fellow - Vancouver, British Columbia (CA) job with University of British Columbia Department of Surgery | 12837375 The successful candidate will work on a project developing cell-based therapies for those living with type 1 diabetes (T1D).

We're looking for postdoctoral scholars to join our team in Vancouver 🇨🇦. We work on cell-based approaches aimed at curing type 1 diabetes. Bring your own ideas for projects or work on one that's already funded! More details here: www.nature.com/naturecareer...

Mr Milchick is reviewer 3 though.

Outside picture in the snow of ~75 attendees at the A-BC Islet Workshop in Silver Star.

Beautiful sunrise at about 7:30 AM over the Monashee(?) Mountains to the east of Silver Star.

Kicking off the ~15th annual A-BC Islet Workshop at beautiful Silver Star resort in BC. Great islet talks from trainees and keynotes @linnemannlab.bsky.social and @soleimanpourlab.bsky.social
@ubcdiabetes.bsky.social

Fantastic opportunity for fellowship in an excellent T1D research training environment working in regenerative medicine and stem cells in the Breakthrough T1D Centre of Excellence at UBC. If you missed the NOI deadline, no worries, you can still apply! Reach out if you have any questions.

How a Canadian scientist and a venomous lizard helped pave the way for Ozempic - National | Globalnews.ca In 1984, Dr. Daniel Drucker, an endocrinologist from the University of Toronto, discovered a hormone that helped pave the way for popular diabetes drugs such as Ozempic.

This is the most relevant article to NIH and research cuts I’ve seen.

Imagine if this was today , how many people would be saying “Why are we studying Gila Monsters and their impact on diabetes ? That’s wasted money !”

globalnews.ca/news/9793403...

We have room and $ for postdoctoral fellows to join our team in beautiful Vancouver 🇨🇦. Get in touch if interested.

Well done Scott and team and Pat! Looks like a very nice prep!

Research Associate Academic Job Category Faculty Non Bargaining Job Title Research Associate Department Johnson Laboratory | Department of Cellular and Physiological Sciences | Faculty of Medicine (James Johnson) Postin...

ubc.wd10.myworkdayjobs.com/en-US/ubcfac...

We are looking for an imaging master to run a very cool shared microscope - Raman label-free, 2-photon, FLIM, high-res, fast capture, thick live tissue, organoids, high-content screening. We are a dynamic and supportive and fun environment.

Looking forward to the shipment, thanks for the support!

🚀 Excited to announce that our Lab @UBC is recruiting!
🌟 We're looking for passionate intern, graduate, and postdoc with strong coding/ML backgrounds to join us in advancing AI for single-cell biology & brain-computer interfaces.
🏔️ Vancouver awaits!
👉 tanglab.msl.ubc.ca
📧 xin.tang@msl.ubc.ca

Inceptor binds to and directs insulin towards lysosomal degradation in β cells - Nature Metabolism The insulin inhibitory receptor (inceptor) is found to bind to insulin and to regulate insulin stores by directing proinsulin and insulin towards lysosomal degradation.

Thrilled to share one of our biggest discoveries: “Inceptor binds to and directs insulin towards lysosomal degradation in beta cells”.
doi.org/10.1038/s422...
A tremendous collaborative effort led by JohannaSiehler, Sara Bilekova and other members of the Lickert lab @heikolickert.bsky.social

Great to have this paper out in diabetesjournals.org/diabetes! Appreciate the feedback from reviewers and funding from BreakthroughT1D that made this work possible. pubmed.ncbi.nlm.nih.gov/39561351/

And in an effort to build community (after I saw the Swiss starter pack! ) - here's one for scientists in Canada! Let me know who I missed.
go.bsky.app/4owyF32

@nictitate.bsky.social deservedly recognized for his outstanding mentorship at the 3rd Canadian Islet Research Training Network meeting in Halifax

@bruinjenny1.bsky.social kicking off the 3rd annual Canadian Islet Research Training Network (CIRTN) meeting in Halifax by thanking sponsors, including our BC Diabetes Research Network and Canucks for Kids Fund Childhood Diabetes Labs at BC Children's Hospital! Two days of trainee led islet biology!

Who doesn’t love talking #islet biology??!!!

wow what's that like?!

Keynote speaker Dr. Anna Gloyn kicking off our 11th Annual Vancouver Diabetes Research Day (VDRD) on Nov 14, World Diabetes Day, supported by the BC Diabetes Research Network