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Dita Gratzinger

@patholog.bsky.social

Physician-Scientist Hematopathologist Medsky

147 Followers  |  131 Following  |  8 Posts  |  Joined: 03.11.2024  |  2.0335

Latest posts by patholog.bsky.social on Bluesky

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Medicine Nobel goes to scientists who revealed secrets of immune system β€˜regulation’ Mary Brunkow, Fred Ramsdell and Shimon Sakaguchi discovered cells that protect the body from autoimmune diseases.

This year’s Nobel Prize in Physiology or Medicine has been awarded to Mary Brunkow, Fred Ramsdell, and Shimon Sakaguchi for discovering a class of immune cells that help to prevent the body from attacking its own tissues. #medsky πŸ§ͺ

06.10.2025 13:55 β€” πŸ‘ 77    πŸ” 25    πŸ’¬ 0    πŸ“Œ 1

Did you check a little ways behind you, amongst the ferns?

26.09.2025 04:31 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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AOC: We should be clear about who Charlie Kirk was. A man who believed that the civil rights act that granted black Americans the right to vote was a mistake… His rhetoric and beliefs were ignorant, uneducated, and sought to disenfranchise millions of Americans.

19.09.2025 16:19 β€” πŸ‘ 31145    πŸ” 7946    πŸ’¬ 638    πŸ“Œ 427
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The FG Phase and Transport Through Nuclear Pores In this Viewpoint, 2025 Albert Lasker Basic Medical Research Award winner Dirk GΓΆrlich describes discoveries that exposed the structures and functions of protein sequences of low complexity,…

In his own wordsβ€”#LaskerAward winner Dirk GΓΆrlich explains the scientific thinking behind discovering the critical functions of low-complexity domains within protein sequences. πŸ§ͺ
#Lasker2025 #phaseseparation
@JAMA.com @mpi-nat.bsky.social
jamanetwork.com/journals/jam...

17.09.2025 12:45 β€” πŸ‘ 4    πŸ” 2    πŸ’¬ 0    πŸ“Œ 0

New faculty position opening at @stanford-chemh.bsky.social . Especially interested in candidates with deep expertise and vision for the future of AI/ML/computational models of biomolecules. Please RT

17.09.2025 18:29 β€” πŸ‘ 15    πŸ” 8    πŸ’¬ 0    πŸ“Œ 0
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#StanfordWIM Ami Bhatt is reshaping microbiome science by leading the largest study of its kind in Africa. Her work has uncovered 1,000+ new bacterial genomes & 40,000+ viral genomes β€” expanding our global understanding of health & disease. https://stanford.io/4hlgmPd

17.09.2025 16:51 β€” πŸ‘ 6    πŸ” 1    πŸ’¬ 1    πŸ“Œ 0
JAMA article from September 11, 2025, features Lucy Shapiro, PhD, recipient of the 2025 Lasker-Koshland Special Achievement Award in Medical Science. The article, titled "The Logic of Cellular Life," details her career.

JAMA article from September 11, 2025, features Lucy Shapiro, PhD, recipient of the 2025 Lasker-Koshland Special Achievement Award in Medical Science. The article, titled "The Logic of Cellular Life," details her career.

2025 Lasker~Koshland Special Achievement Award in Medical Science winner Dr Lucy Shapiro discusses her discovery of how bacteria coordinate their genetic logic to generate distinct daughter cells.

#LaskerAward #Lasker25 @laskerfdn.bsky.social

ja.ma/46vPmcF

11.09.2025 13:15 β€” πŸ‘ 22    πŸ” 11    πŸ’¬ 0    πŸ“Œ 0
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@who.int is appalled by the latest evacuation order, demanding 1 million people to move from Gaza City to a β€œhumanitarian zone” in the south.

To civilians: WHO and partners remain in Gaza City.

To the intl. community: Act.

This catastrophe is human-made, & the responsibility rests with us all.

10.09.2025 19:04 β€” πŸ‘ 114    πŸ” 55    πŸ’¬ 2    πŸ“Œ 1
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Hematopoietic stem and progenitor cells as a reservoir for trained immunity Inflammation supports selection, differentiation bias, and epigenetic reprogramming of hematopoietic stem and progenitor cells to generate innate immune memory.

Central trained immunity is still a nascent fieldβ€” is there true reprogramming of hematopoietic progenitors to influence innate immunity, or is this selection for lineage biased cells? We explore the nuances in this new review. doi.org/10.7554/eLif... awesome collab with Eva Kaufmann and team!

08.09.2025 12:40 β€” πŸ‘ 2    πŸ” 2    πŸ’¬ 1    πŸ“Œ 0
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Acetaminophen remains a safe pain relief option during pregnancy. Despite recent unfounded claims, there’s no clear evidence linking prudent use to fetal development issues. ACOG's guidance remains. When needed in pregnancy, acetaminophen should be used in moderation, after consulting a doctor.

05.09.2025 20:20 β€” πŸ‘ 233    πŸ” 115    πŸ’¬ 6    πŸ“Œ 7
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Opinion | We Ran the C.D.C.: Kennedy Is Endangering Every American’s Health

This morning 9 former CDC Directors, whose tenures date back to 1977, published this warning in the NYT:

RFK Jr is a danger to public health.

www.nytimes.com/2025/09/01/o...

01.09.2025 10:45 β€” πŸ‘ 1401    πŸ” 532    πŸ’¬ 26    πŸ“Œ 23
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17x17K in Sunnyvale, CA!
17 miles of protest from Redwood City to San Jose. Sunnyvale represented!
#dumptrump #impeachtrump #17Γ—17k #indivisible #handsoff #50501movement #goodtrouble #protest #stopICE

01.09.2025 20:21 β€” πŸ‘ 25    πŸ” 6    πŸ’¬ 1    πŸ“Œ 1
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Massive protest in South Bay 17 miles of people

01.09.2025 19:58 β€” πŸ‘ 155    πŸ” 33    πŸ’¬ 1    πŸ“Œ 0
A red white and blue flier that reads "HISTORIC 17X17K 17 miles of resistance, 17,000+ resisters 

Join us on Labor day Sept 1, 2025 11am-1pm 
El Camino Real (south/west side of the street) from Santa Clara to Redwood City 

Join us for a 17-mile-long protest in place, pick your spot, amd help stretch the line! Bring flags, signs, lawn chairs, and friends. 

A link to RRVP is included 

Organized by Sally Lieber, IdaRose Sylvester, Together We Will, Mountain View Voices for Peace

A red white and blue flier that reads "HISTORIC 17X17K 17 miles of resistance, 17,000+ resisters Join us on Labor day Sept 1, 2025 11am-1pm El Camino Real (south/west side of the street) from Santa Clara to Redwood City Join us for a 17-mile-long protest in place, pick your spot, amd help stretch the line! Bring flags, signs, lawn chairs, and friends. A link to RRVP is included Organized by Sally Lieber, IdaRose Sylvester, Together We Will, Mountain View Voices for Peace

Heyo! Good morning!

It's Labor Day and that means this 17-mile protest along El Camino Real from #RedwoodCityCA to #SantaClaraCA is taking place.

01.09.2025 18:05 β€” πŸ‘ 40    πŸ” 10    πŸ’¬ 1    πŸ“Œ 2
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RFK Jr.’s damage to the CDC is β€˜past the point of no return,’ Dr. Demetre Daskalakis warns β€œThe CDC you knew is over,” the infectious diseases doctor told The Advocate. β€œUnless someone takes radical action, there is nothing there that can be salvaged.”

there is no question in my mind that rfk jr is the most dangerous person in this administration and that his eugenicist ideology threatens the lives of millions of people www.advocate.com/politics/dem...

29.08.2025 20:53 β€” πŸ‘ 28313    πŸ” 8921    πŸ’¬ 487    πŸ“Œ 466
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Fire risk to structures in California’s Wildland-Urban Interface - Nature Communications Wildfire risk in California’s WUI is rising. Analysis of past events shows home hardening and defensible space can reduce structure loss by up to 52%, but coordinated, community-scale action is essent...

California communities can reduce wildfire damage by half. Here’s how:
Our new study "Fire risk to structures in California’s Wildland-Urban Interface" was published in Nature Communications today! www.nature.com/articles/s41...
news.berkeley.edu/2025/08/28/c...

29.08.2025 16:57 β€” πŸ‘ 53    πŸ” 18    πŸ’¬ 3    πŸ“Œ 2
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Infants under six months old have the highest rates of #COVID19-related hospitalization save for adults 75 years and older. COVID-19 vaccination during pregnancy reduces the risk of severe illness and death. Encourage your patients to protect themselves and their newborns. Learn more: bit.ly/3RWsM3z

27.08.2025 17:33 β€” πŸ‘ 95    πŸ” 57    πŸ’¬ 2    πŸ“Œ 2

If you want to put back statues and memorials and names of Confederate traitors while tearing down museum exhibitions on slavery because they don't show the greatness of the nation... the nation whose history you're celebrating is whiteness. The kind of nationalist you are is a white nationalist.

19.08.2025 21:50 β€” πŸ‘ 17495    πŸ” 5056    πŸ’¬ 311    πŸ“Œ 196
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🚨New paper 🚨

Can protein language models help us fight viral outbreaks? Not yet. Here’s why πŸ§΅πŸ‘‡
1/12

17.08.2025 03:42 β€” πŸ‘ 42    πŸ” 19    πŸ’¬ 3    πŸ“Œ 0
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Platelets sequester and harbor cell-free tumor DNA, which could enhance our ability to make early, microscopic diagnosis of cancer
@science.org

science.org/doi/10.1126/...
science.org/doi/10.1126/...

14.08.2025 21:39 β€” πŸ‘ 253    πŸ” 57    πŸ’¬ 6    πŸ“Œ 1
Recommendations for Tumor Mutational Burden Assay Validation and Reporting Tumor mutational burden (TMB) has been recognized as a predictive biomarker for immunotherapy response in several tumor types. Several laboratories offer TMB testing, but there is significant variation in how TMB is calculated, reported, and interpreted among laboratories. TMB standardization efforts are underway, but no published guidance for TMB validation and reporting is currently available. Recognizing the current challenges of clinical TMB testing, the Association for Molecular Patholog...

#LegacyContent: Recommendations for Tumor Mutational Burden Assay Validation and Reporting: A Joint Consensus Recommendation of the @ampath.bsky.social, @pathologists.bsky.social

https://loom.ly/5ZvWjRw

11.08.2025 07:05 β€” πŸ‘ 2    πŸ” 2    πŸ’¬ 0    πŸ“Œ 0
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Congratulations to CAP President-Elect 2025–2027 Kalisha Ashara Hill, MD, MBA, FCAP.

08.08.2025 15:24 β€” πŸ‘ 1    πŸ” 1    πŸ’¬ 1    πŸ“Œ 0
Graphic requesting volunteers to co-moderate sessions at the AMP 2025 Annual Meeting & Expo in Boston in November. Applications due by August 11 at 11:59 p.m. Eastern.

Graphic requesting volunteers to co-moderate sessions at the AMP 2025 Annual Meeting & Expo in Boston in November. Applications due by August 11 at 11:59 p.m. Eastern.

There are only 3 days left to apply to co-moderate a session at #AMPath2025!

Early- to mid-career members with backgrounds in informatics, infectious diseases and tech topics are strongly encouraged to apply.

πŸ’‘Apply by Aug. 11 at 11:59 p.m. Eastern.

ampvolunteer.secure-...

08.08.2025 14:00 β€” πŸ‘ 1    πŸ” 1    πŸ’¬ 0    πŸ“Œ 0
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HHS scraps further work on life-saving #mRNA vaccine platform

Experts say the move risks national security by leaving the United States vulnerable to the next pandemic virus.

www.cidrap.umn.edu/c...

06.08.2025 18:49 β€” πŸ‘ 22    πŸ” 24    πŸ’¬ 1    πŸ“Œ 3
The Story of Pathology Workforce in Sub Saharan Africa
YouTube video by Pathologists Overseas The Story of Pathology Workforce in Sub Saharan Africa

If you are a pathologist or represent a pathology training program in Sub Saharan Africa your input is essential!

Complete the survey by clicking the link below:
redcapsurveys.med.usc.edu/surveys/?s=8...

#Africa #Lab #AfricaSky #PathSky #GlobalHealth #Pathology #PublicHealth

youtu.be/xnj0VgYplQc

06.08.2025 18:24 β€” πŸ‘ 3    πŸ” 2    πŸ’¬ 1    πŸ“Œ 0
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ACOG No Longer Accepting Federal Funding, Citing Policy Disputes May be the first physician organization to divest from federal funds this way

ACOG No Longer Accepting Federal Funding, Citing Policy Disputes www.medpagetoday.com/obgyn/genera...

01.08.2025 20:47 β€” πŸ‘ 69    πŸ” 29    πŸ’¬ 4    πŸ“Œ 4

Many big & alarming stories last week marking an acceleration in the unraveling of this country, but one not getting enough outrage is Trump accusing former President Obama of treason. Despicable, sick, unconscionable. A major line-crossing action that warranted loud & widespread denunciation.

27.07.2025 14:55 β€” πŸ‘ 2045    πŸ” 485    πŸ’¬ 46    πŸ“Œ 21

There’s nothing the slightest bit controversial about pointing out how terrible this is.

I know a lot of US doctors that are concerned about losing something from sharing their feelings on the matter and I implore you to not let that stop you.

27.07.2025 15:42 β€” πŸ‘ 27    πŸ” 3    πŸ’¬ 2    πŸ“Œ 0
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Outbreak of Salmonella Typhimurium Infections Linked ... This report describes a Salmonella outbreak linked to ...

The CDC describes this salmonella outbreak as β€œone of the largest foodborne outbreaks linked to raw milk in recent U.S. history.” Out of the 171 people who got sick, 70% were children. The median age was 7 years old. Even worse, 18 children had to be hospitalized. Please do not consume raw milk.

25.07.2025 10:16 β€” πŸ‘ 88    πŸ” 45    πŸ’¬ 7    πŸ“Œ 6
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Disease-associated loci share properties with response eQTLs under common environmental exposures Many of the genetic loci associated with disease are expected to have context-dependent regulatory effects that are underrepresented in the transcriptomes of healthy, steady-state adult tissues. To un...

If we want to connect genetic variation to disease, we need to move beyond baseline conditions. Our study shows that dynamic, context-specific regulation holds the key to understanding many unexplained GWAS signals. The preprint again:

www.biorxiv.org/content/10.1...

10.06.2025 14:20 β€” πŸ‘ 23    πŸ” 11    πŸ’¬ 1    πŸ“Œ 0

@patholog is following 20 prominent accounts