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Julia Ugras

@juliaugras.bsky.social

Cancer Biology PhD Candidate in the Lyssiotis Lab at the University of Michigan | Uridine & Pancreatic Cancer

65 Followers  |  98 Following  |  8 Posts  |  Joined: 18.11.2024  |  1.8299

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Uridine Uridine is a pyrimidine nucleoside composed of an uracil base and a ribose sugar. In cells, uridine is predominantly present in RNA (as uridine monophosphate, UMP). Uridine can be produced through de novo UMP synthesis or salvaged from the blood or intracellular sources like RNA. Under energy stress, uridine is catabolized by uridine phosphorylase (UPP1, UPP2) into uracil and ribose 1-phosphate, where the ribose enters central carbon metabolism to support bioenergetics. Uracil, once considered waste, may have extracellular signaling roles.

Online Now: Uridine #trends #endocrinology #metabolism

12.06.2025 12:23 โ€” ๐Ÿ‘ 0    ๐Ÿ” 1    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

Thanks for the highlight @frezzalab.bsky.social ! Check out our highlight on Uridine as the Metabolite of the Month in @cellpress.bsky.social ! @lyssiotislab.bsky.social ๐Ÿงฌ

17.06.2025 12:55 โ€” ๐Ÿ‘ 3    ๐Ÿ” 0    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 0

Thank you Federica!!!

17.06.2025 12:53 โ€” ๐Ÿ‘ 1    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

Go Caleb!!!

24.04.2025 19:14 โ€” ๐Ÿ‘ 1    ๐Ÿ” 0    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 0

Beyond grateful to share that my main PhD thesis project, Targeting PIKfyve-driven lipid metabolism in pancreatic cancer (@lyssiotislab.bsky.social + Arul Chinnaiyan lab), has just been published in @nature.com!

24.04.2025 15:19 โ€” ๐Ÿ‘ 12    ๐Ÿ” 6    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 2

Proud to be a part of this important NIH funded work with @mckinnonwalsh.bsky.social, @bailey-bye.bsky.social and other colleagues from the @vansaunlab.bsky.social!

27.03.2025 16:29 โ€” ๐Ÿ‘ 6    ๐Ÿ” 2    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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The @lyssiotislab.bsky.social and the Cancer Biology Program were out in full force at the One Day Closer to a Cure event. Annually, we host activities for high school students to learn about careers in cancer research and patient care. Special shoutout to Katie for an amazing patient story!

15.03.2025 17:44 โ€” ๐Ÿ‘ 8    ๐Ÿ” 5    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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Yesterday, the House passed an FY25 budget bill that slashes funding to the Pancreatic Cancer Research Program by 57%.

Research for pancreatic cancer is already woefully underfunded, and now the only program exclusively funding pancreatic cancer research is one step closer to devastating cuts.

13.03.2025 00:20 โ€” ๐Ÿ‘ 4    ๐Ÿ” 6    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 1
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Francis Collins, the NIH Director for 12 years, led the Human Genome Project and other NIH efforts for 32 years, resigned today. Key words from his resignation letter
www.nytimes.com/2025/03/01/u...

01.03.2025 18:07 โ€” ๐Ÿ‘ 3159    ๐Ÿ” 1398    ๐Ÿ’ฌ 62    ๐Ÿ“Œ 95

FLY EAGLES FLY ๐Ÿฆ…๐Ÿฆ…๐Ÿฆ…

10.02.2025 03:19 โ€” ๐Ÿ‘ 0    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
lab picture

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defense picture

defense picture

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Crazy that I defended on Friday! Really appreciate everything I learned from Yatrik and @lyssiotislab.bsky.social over the years! Can't ask for better mentors, labs, colleagues, friends, and support over the years!

Next step, postdoc with Kivanc Birsoy at Rockefeller University !๐Ÿงฟ๐Ÿ—ฝ

20.01.2025 16:17 โ€” ๐Ÿ‘ 32    ๐Ÿ” 3    ๐Ÿ’ฌ 4    ๐Ÿ“Œ 0

Super excited for @brandontwchen.bsky.social โ€˜s defense, but equally as sad to see him go ๐Ÿซถ๐Ÿฅฒ

03.01.2025 19:28 โ€” ๐Ÿ‘ 3    ๐Ÿ” 0    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 0

Carrie would love some multiplex

27.11.2024 02:38 โ€” ๐Ÿ‘ 1    ๐Ÿ” 0    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 0
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Undergrads, looking for a summer research opportunity in cancer biology? Consider applying for a CARSIP position! Details below ๐Ÿ‘‡๐Ÿผ
Please [re] circulate widely ๐Ÿ”!

25.11.2024 22:33 โ€” ๐Ÿ‘ 11    ๐Ÿ” 6    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
Image of multiplex immunofluoresence staining

Image of multiplex immunofluoresence staining

Getting some pretty IF images done with @mruckert.bsky.social on the @leicamicrosystems.bsky.social Stellaris before Thanksgiving break ๐Ÿคฉ๐Ÿ‚

26.11.2024 20:37 โ€” ๐Ÿ‘ 8    ๐Ÿ” 2    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

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