Nanion Technologies

Join the discussion at our #BPS2026 posters

We’ll be sharing and discussing data across ion channels, transporters & membrane biophysics.

And while you’re there, stop by Booth #528, we have special news to share 👀

About the posters: https://ow.ly/9rkT50Y7vkQ

#BPS2026 #Posters #APC #Biophysics

Looking back at MPS 2025 in Napa Valley

A meeting report published in Bioelectricity documents the scientific scope and discussions of the Membrane Physiology Symposium.

These principles continue to guide MPS 2026, returning to Napa Valley in April 14-15, 2026.

https://ow.ly/B14Q50YbxJJ

Live transporter recordings at #BPS2026

Real-time SSME on the SURFE²R N1, measured live on site.
Limited spots available, register to attend the live demos.
https://ow.ly/1svz50Y9g3R

#BPS2026 #Transporters #TMEM175 #SSME #Lysosomes #Electrophysiology #Collaboration

Join our exhibitor presentation at #BPS2026 🔬

We’ll be discussing electrophysiological tools advancing ion channel & transporter drug discovery.

Looking forward to the discussion with the community.

Learn about our activities at BPS: https://ow.ly/3JYw50Y7uuP

We’re hosting SURFE²R N1 live demo sessions at #BPS2026
𝗡𝗼𝘁 𝗽𝗿𝗲-𝗿𝗲𝗰𝗼𝗿𝗱𝗲𝗱. 𝗡𝗼𝘁 𝘀𝗶𝗺𝘂𝗹𝗮𝘁𝗲𝗱. 𝗥𝗲𝗰𝗼𝗿𝗱𝗲𝗱 𝗹𝗶𝘃𝗲 𝗮𝘁 𝗕𝗣𝗦.

📍 Moscone Center, Esplanade Room 158
📅 Two live sessions:
Sunday, Feb 22 | 12:30–2:00 PM
Monday, Feb 23 | 12:30–2:00 PM

Register here: https://ow.ly/B00250Y4SAi

Attending WSCC26 in Grindelwald? Let’s connect.

Feb 4–6, the global sodium channel community meets in person. Our Senior Scientist Markus Rapedius will be on site and presenting a poster on APC-based analysis of excitability in ALS iPSC-derived motor neurons (with Axol).

#WSCC26 #SodiumChannels

We’re pleased to announce Prof. Glenn King and his team at the Institute for Molecular Bioscience, The University of Queensland, as winners of the 2025 SyncroPatch 384 Research Grant.

Congratulations to Prof. King and team 👏

Learn more: https://ow.ly/NQVn50XZLzX

#IonChannels #Grant #APC

We’re pleased to announce Medha Pathak (UC Irvine, US) as a winner of the 2025 SyncroPatch 384 Research Grant, together with co-PIs Francesco Tombola, Jerome Lacroix, and Lyna Luo.

Congratulations to the entire team 👏

More details here: https://ow.ly/K3Pf50XZLic

#IonChannels #APC #Grant

𝗙𝗲𝗯𝗿𝘂𝗮𝗿𝘆 = 𝗕𝗶𝗼𝗽𝗵𝘆𝘀𝗶𝗰𝗮𝗹 𝗦𝗼𝗰𝗶𝗲𝘁𝘆 𝗺𝗼𝗻𝘁𝗵 🔬

We’re heading to #BPS2026 with a full program of activities.
Find us at Booth #528 for live demos and discussions on ion channels, transporters & biophysics.

Will you be there?
https://ow.ly/79Yi50XZBkg

#Events #APC #Biophysics

𝟮𝟰 𝘆𝗲𝗮𝗿𝘀 𝗼𝗳 𝗡𝗮𝗻𝗶𝗼𝗻, 𝗱𝗿𝗶𝘃𝗲𝗻 𝗯𝘆 𝘀𝗰𝗶𝗲𝗻𝗰𝗲 𝗮𝗻𝗱 𝗰𝗼𝗹𝗹𝗮𝗯𝗼𝗿𝗮𝘁𝗶𝗼𝗻 🎉

As we start 2026, we’re grateful for a year shaped by community, exchange, and shared progress. We’ve captured key moments from 2025 in our Annual Review.

Read more 👉 https://ow.ly/VmJC50XXc4z

#TeamNanion #Anniversary

Why early safety assessment needs a new approach

Animal models and simple assays often miss human-specific risk.
New Approach Methodologies (NAMs) combine human-relevant biology with scalable in vitro tools to enable earlier, more predictive safety insight.

Read more: https://ow.ly/Bm5650XWCKU

Renal ion channels have been linked to kidney disease for decades, yet they remain underexplored as drug targets.

This blog connects basic channel biology with ongoing drug discovery efforts, from APOL1 to TRPC and PKD.

Read the full blog: https://ow.ly/lJjg50XW5Eb

#APC #IonChannels

SyncroPatch 384 Research Grant - Nanion Technologies In 2025, we are offering the chance for you to win a SyncroPatch 384 for 9 months.

𝗔𝗽𝗽𝗹𝗶𝗰𝗮𝘁𝗶𝗼𝗻𝘀 𝗮𝗿𝗲 𝗼𝗽𝗲𝗻 𝗳𝗼𝗿 𝘁𝗵𝗲 𝗦𝘆𝗻𝗰𝗿𝗼𝗣𝗮𝘁𝗰𝗵 𝟯𝟴𝟰 𝗥𝗲𝘀𝗲𝗮𝗿𝗰𝗵 𝗚𝗿𝗮𝗻𝘁!

Get 9 months with the system, consumables, and full support to accelerate your research.

Deadline: Oct 31. Apply now!

ow.ly/9gx050X0OOW

#APC #IonChannels #Electrophysiology

Reduce variability in NaV studies with adaptive voltage clamp on the SyncroPatch 384.

Tailor Vhalf per well, gain better IC50 precision, and study state-dependent effects with confidence.

Check out the flyer to see how it works!
ow.ly/8QMU50WFXei

#APC #IonChannels #NaV #Electrophysiology

How do CaV1.2 mutations drive both arrhythmias and neuro symptoms in Timothy syndrome?

Join Ivy Dick on June 12 to learn how high-throughput patch clamp reveals mutation-specific gating changes tied to clinical outcomes.

📍https://ow.ly/PxZY50W72H7

#PatchClamp #Channelopathies #IonChannels

Automated patch clamp for ENaC drug discovery - Nanion Technologies The epithelial sodium channel (ENaC) plays a central role in regulating sodium balance, blood pressure, and pulmonary fluid clearance. Despite its clinical relevance, progress in discovering new ENaC-...

In a recent study, researchers developed and validated an automated #patchclamp ( #APC ) approach using the SyncroPatch 384 platform to detect #ENaC - mediated currents in a high-throughput format.

Read more here:
www.nanion.de/news/automat...

Most cardiac gene variants are still classed as “uncertain.”

Join us on Thursday to learn how APC is helping reclassify VUS and improve clinical decisions.

🗓️ May 8 | 16:00–17:00 CEST
🔗 ow.ly/RQfB50VFl93

Hope to see you there!
#CardiacGenetics #APC #VUS #LQTS #Brugada

How do beta-lactam antibiotics get into our cells, and how can we use that to design better drugs?

Join our webinar on May 14 to explore new insights into PepT2, drug uptake, and delivery.

🔗 Register: ow.ly/1mCL50Vo2j8

#PepT2 #DrugDesign #CryoEM #Webinar

Why is NHE9 active in endosomes but silent at the membrane?

A new Nature Communications study reveals a lipid switch: PI(3,5)P₂ stabilizes NHE9’s dimer only in endosomes.

🔗Read the full article to find out more: ow.ly/zrsR50VAAZW

#MembraneTransport #CryoEM #SSME

Webinar: Understanding antibiotic uptake via PepT2 - Nanion Technologies Date: May 14, 2025 Time: 16:00 – 17:00 CEST Location: Online via Zoom

Join us in exactly one month for our next transporters webinar!

Dr. Joanne Parker (University of Oxford) will present research insights on PepT2 (SLC15A2), a key player in beta-lactam antibiotic transport.

📅 May 14, 2025 | 🕓 16:00–17:00 CEST

🔗 Register here: ow.ly/1mCL50Vo2j8

#MembraneTransport

𝗖𝗮𝗻 𝘄𝗲 𝗶𝗺𝗽𝗿𝗼𝘃𝗲 𝘁𝗵𝗲 𝘄𝗮𝘆 𝘄𝗲 𝗶𝗻𝘁𝗲𝗿𝗽𝗿𝗲𝘁 𝗰𝗮𝗿𝗱𝗶𝗮𝗰 𝗴𝗲𝗻𝗲 𝘃𝗮𝗿𝗶𝗮𝗻𝘁𝘀?

Join Dr. Chai Ng (Victor Chang Cardiac Research Institute) on May 8 to explore APC’s role in variant classification for inherited arrhythmias.

🔗 ow.ly/XrnO50VymFI

#Webinar @chaiannng.bsky.social @victorchang.edu.au

iPSC-CMs are powerful, but their immaturity limits their predictive value. A recent study from TU Dresden shows how combining metabolic medium, nanopatterning, and electrostimulation significantly enhances structural and electrophysiological maturation.

🔗 lnkd.in/dipXpmyN

#Cardiac #iPSC #APC

TRPV3 is a temperature-sensitive, ligand-gated ion channel known for its role in warmth perception.

It can be activated by heat (~ 38˚C) or by 2-APB, and we have explored both activation modes using APC with temp control.

Read the app note: ow.ly/YMp850R6hwG
#TRPV3 #IonChannels #Electrophysiology

Cryo-EM reveals how cholesterol and sphingomyelin shape the structure and stability of a membrane pore formed by the toxin Fav.

Electrophysiology with the Orbit Mini confirms cholesterol reduces current noise.

🔗 Read more in the paper: ow.ly/sPmJ50VusCf

#CryoEM #MembraneBiophysics #Orbitmini

𝗛𝗼𝘄 𝗱𝗼 𝗯𝗲𝘁𝗮-𝗹𝗮𝗰𝘁𝗮𝗺 𝗮𝗻𝘁𝗶𝗯𝗶𝗼𝘁𝗶𝗰𝘀 𝗲𝗻𝘁𝗲𝗿 𝘁𝗵𝗲 𝗯𝗼𝗱𝘆?
And why does it matter for drug design?

Join us on May 14 as Joanne Parker (University of Oxford) presents new insights into the structure and function of PepT2, a key transporter in beta-lactam pharmacokinetics.
ow.ly/1mCL50Vo2j8

#MembraneTransport

Understanding cardiac function needs more than one readout

This flyer shows how combining electrophysiology, contractility & viability data offers deeper insights into drug effects & disease models.

Discover more in the flyer: ow.ly/LGRs50VnV0o

#CardiacResearch #iPSC

Studying pore-forming toxins? At Nanion, we provide advanced tools - parallel bilayer recording stations, GUVs, and planar patch clamp systems - to help researchers get a clearer picture of how these toxins work.

Learn more: www.linkedin.com/feed/update/...

#PFT #toxins #electrophysiology

Working with toxins & ion channels? Testing multiple fractions and screening channels with limited samples is tough. That’s why more scientists are turning to automated patch clamp for faster, reliable results. Curious? Learn more: www.nanion.de/application-... #ionchannels #toxins #patchclamp

𝗝𝗼𝗶𝗻 𝘂𝘀 𝗮𝘁 𝘁𝗵𝗲 𝗠𝗲𝗺𝗯𝗿𝗮𝗻𝗲 𝗣𝗵𝘆𝘀𝗶𝗼𝗹𝗼𝗴𝘆 𝗦𝘆𝗺𝗽𝗼𝘀𝗶𝘂𝗺!

From ion channels to drug discovery—discover what’s next in electrophysiology. Connect with leading experts in Napa Valley!

📅 Apr 30–May 1

𝗟𝗶𝗺𝗶𝘁𝗲𝗱-𝗧𝗶𝗺𝗲 𝗢𝗳𝗳𝗲𝗿: 𝟭𝟱% 𝗢𝗳𝗳 𝗧𝗶𝗰𝗸𝗲𝘁𝘀
Register now 🔗 ow.ly/SmfE50VgoHz

#MPS25 #MembranePhysiology

Venom-derived toxins offer unique precision in ion channel research. We tested Huwentoxin-IV, TTX, GsMTx4 & α-Conotoxin MI on NaV1.7 and nAChR to explore their blocking effects. Want to learn more?
Read more in the full study: ow.ly/bKoG50Vgpy3
#IonChannels #DrugDiscovery #APC