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Justin Lines

@jlines.bsky.social

Neuroscientist. Plays with microscopes and ECoG to study network activity in health and disease. Postdoc in the lab of Denise Cai. I also ๐ŸŽฎ and โ›น๏ธ

115 Followers  |  141 Following  |  4 Posts  |  Joined: 25.11.2024  |  1.3628

Latest posts by jlines.bsky.social on Bluesky

Did you see him help someone?
Did you see him try to run?
Did you see them six-on-one?
Did you see them take his gun?
Did you see that it was done?
Did you see him get shot a dozen times in broad daylight?

Do you think they'll kill again?

26.01.2026 15:08 โ€” ๐Ÿ‘ 0    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

Party ๐Ÿ‘€

18.11.2025 01:51 โ€” ๐Ÿ‘ 1    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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WOW! 372 "astrocyte" presentations this year at #SfN2023 @SfNTweets

Not enough talks - let's work on this for 2024. Full roundup below. I am SURE I have missed some, so please reply with more! Daily session roundups to come for each session. See you all soon.
#SocietyForGlia

10.11.2023 23:20 โ€” ๐Ÿ‘ 9    ๐Ÿ” 2    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 0
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#SfN25 #SocietyForGlia #Astrocytes

@borderbiologist.bsky.social presenting now!
Come and learn about a new function for a substate of reactive astrocytes - antigen presentation!

15.11.2025 20:33 โ€” ๐Ÿ‘ 13    ๐Ÿ” 1    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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#SocietyForGlia #SfN25 #Astrocytes

Astrocyte presentation round up for Day 1.
Sorry if I missed anyone, please comment below with others!

See you about the conference

15.11.2025 20:35 โ€” ๐Ÿ‘ 10    ๐Ÿ” 2    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 0
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It has been an immense honor to learn & grow with two of the greatest scientists I know: @zachtpennington.bsky.social & @joezaki.bsky.social ๐Ÿง‘โ€๐Ÿ”ฌ

Listen in on our conversation about mentorship, building trust and creating a safe space to disagree: neuronline.sfn.org/professional...

03.10.2025 20:33 โ€” ๐Ÿ‘ 18    ๐Ÿ” 5    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 2

Excited to share that I landed my dream job!๐ŸŽ‰๐ŸŽ‰๐ŸŽ‰ The Pennington Lab will be opening at the University of British Columbia in January 2026!
@ubcpsych.bsky.social @dmcbrainhealth.bsky.social

29.09.2025 16:31 โ€” ๐Ÿ‘ 156    ๐Ÿ” 29    ๐Ÿ’ฌ 29    ๐Ÿ“Œ 5
Screenshot of article entitled "Distinct changes to hippocampal and medial entorhinal circuits emerge across the progression of cognitive deficits in epilepsy" by Yu Feng, Keziah S. Diego, Zhe Dong, ..., Nadia N. Khan, Denise J. Cai, and Tristan Shuman. 

In brief: Feng et al. demonstrate that memory deficits in temporal lobe epilepsy involve multiple discrete mechanisms with distinct time courses. In epileptic mice, early-onset memory deficits are associated with disrupted hippocampal synchronization, while more severe, lateonset impairments are associated with disrupted synchrony of medial entorhinal cortex circuits.

Screenshot of article entitled "Distinct changes to hippocampal and medial entorhinal circuits emerge across the progression of cognitive deficits in epilepsy" by Yu Feng, Keziah S. Diego, Zhe Dong, ..., Nadia N. Khan, Denise J. Cai, and Tristan Shuman. In brief: Feng et al. demonstrate that memory deficits in temporal lobe epilepsy involve multiple discrete mechanisms with distinct time courses. In epileptic mice, early-onset memory deficits are associated with disrupted hippocampal synchronization, while more severe, lateonset impairments are associated with disrupted synchrony of medial entorhinal cortex circuits.

New paper out in Cell Reports! Led by @susieyufeng.bsky.social, we found that chronic epilepsy in mice drives distinct synchronization deficits in hippocampus and MEC, with early changes in HPC and late-onset changes in MEC that align with progressive memory impairment.
www.cell.com/cell-reports...

28.01.2025 20:17 โ€” ๐Ÿ‘ 53    ๐Ÿ” 21    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 1
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A spatial threshold for astrocyte calcium surge In astrocytes, there exists an intrinsic spatial threshold of subcellular calcium levels that triggers an astrocyte calcium surge throughout the cell, demonstrating cellular astrocyte calcium integrat...

Astrocyte physiologists and computationalists!

Imaging astrocyte structure and function, we discovered and quantified a spatial threshold to astrocyte calcium surge โญ

doi.org/10.7554/eLif...

20.01.2025 13:53 โ€” ๐Ÿ‘ 8    ๐Ÿ” 1    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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โ“ Do you know what the anterior hypothalamic nucleus (AHN) does? No? Neither did we! ๐Ÿง 

In a new preprint from the Cai Lab, learn how we discovered the AHNโ€™s central role in regulating stress vulnerability.

Read the paper here: www.biorxiv.org/content/10.1... (1/6)

22.11.2024 19:32 โ€” ๐Ÿ‘ 67    ๐Ÿ” 22    ๐Ÿ’ฌ 5    ๐Ÿ“Œ 5

SO EXCITED to share our latest work demonstrating that the anterior hypothalamic nucleus (AHN) regulates stress vulnerability!!!

22.11.2024 20:16 โ€” ๐Ÿ‘ 50    ๐Ÿ” 20    ๐Ÿ’ฌ 3    ๐Ÿ“Œ 0
Nature paper article with title and abstract

Nature paper article with title and abstract

๐ŸŒŸ Cai Lab Nature (@natureportfolio.bsky.social) paper alert! In work led by Joe Zaki, we find that rest periods after learning not only stabilize new memories BUT ALSO integrate new memories with older ones from days past! (1/10)

Read it here: www.nature.com/articles/s41...

19.11.2024 16:49 โ€” ๐Ÿ‘ 260    ๐Ÿ” 90    ๐Ÿ’ฌ 8    ๐Ÿ“Œ 4
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Just showing off some growth

28.11.2024 16:07 โ€” ๐Ÿ‘ 2    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

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