Discovery of functional NLRs using expression level, high-throughput transformation and large-scale phenotyping Nature Plants - Rapid discovery of functional resistance genes is enabled by a high-expression signature and high-throughput transformation. This approach identified 31 new resistance genes for...

Super excited to see our work on the NLRseek program finally published 🥳 Here we identify new NLRs against major wheat pathogens and present a pipeline for NLR identification. Huge thank you to all of the co-authors for bringing this work together! @matthewmoscou.bsky.social rdcu.be/eIGvv

29.09.2025 11:58 — 👍 47    🔁 32    💬 3    📌 0

The Annotated Blueprint: Integrated Functional Genomic Resources for a Model Tetraploid Wheat Triticum turgidum cv. Kronos Triticum turgidum cv. Kronos is a tetraploid wheat cultivar that underpins one of the richest community platforms for functional genomics. Over the past decade, about 3,000 exome- and promoter-capture...

New: ‘Kronos’ #wheat genome preprint
• PacBio+Hi-C; 99.9% BUSCO
• 2.3k curated NLR loci (1,089 high conf)
• 3k EMS datasets re-mapped; 📈 new mutations
• Curated smallRNA atlas
🔗 www.biorxiv.org/content/10.1...
zenodo.org/records/1021...
#genomics #openscience
team effort led by Dr Kyungyong Seong 💫

17.09.2025 17:58 — 👍 14    🔁 6    💬 0    📌 0

Independent Fellowship in Plant-Associated Microbial Interactions | John Innes Centre An exciting opportunity for an Independent Fellowship in Plant-Associated Microbial Interactions has arisen at the John Innes Centre. To read the full job description for this role…

Exciting opportunities to establish your group at JIC! Come join our vibrant research community in Norwich!

🔹 Independent Fellowship in Plant-Associated Microbial Interactions (path to tenure-track)
tinyurl.com/yk576jms
🔹 GL in Discovery Plant Sciences (tenure-track or tenured)
tinyurl.com/mwbs4dhn

21.07.2025 12:53 — 👍 14    🔁 20    💬 0    📌 0

Illustration of four diverse students presenting their final Python course projects in a classroom. A projector screen behind them displays the course title 'PYTHON COURSE' with four project topics: 'Extraction of Genomic Features', 'Development of Molecular Markers from Sequence Variants', 'Analysis of Large Citation Data Sets', and 'Cleaning of FASTA Files'. Two audience members are visible from behind, listening attentively. The students are holding laptops or notes and appear confident and engaged.

Wrapping up our #Python course with inspiring student project presentations! 🚀 Topics range from bioinformatics to big data.
📂 Materials on GitHub: github.com/bpucker/PyBo
#coding #OpenEducation #genomics
@puckerlab.bsky.social

02.05.2025 04:52 — 👍 7    🔁 3    💬 1    📌 0

Concept of MGSE for the estimation of a genome size based on a read mapping. See https://doi.org/10.1186/s12864-025-11640-8 for details

Excited to share the publication of MGSE, our new approach to genome size estimation, in BMC Genomics:
Mapping-based genome size estimation
doi.org/10.1186/s128...
#Genomics #Bioinformatics @puckerlab.bsky.social

21.05.2025 04:31 — 👍 12    🔁 6    💬 0    📌 0

Predicting gene expression from DNA sequence using deep learning models Nature Reviews Genetics, Published online: 13 May 2025; doi:10.1038/s41576-025-00841-2Barbadilla-Martínez et al. review recent progress in deep-learning-based sequence-to-expression models, which predict gene expression levels solely from DNA sequence. These models are providing new insights into the complex combinatorial logic underlying cis-regulatory control of gene expression.

New online! Predicting gene expression from DNA sequence using deep learning models

13.05.2025 17:44 — 👍 21    🔁 9    💬 0    📌 1

Day 3 at BLS meeting @umnplantpath.bsky.social. Proud of my PhD students Muhammad Ahmad and @tapishpwr.bsky.social whose talks on BLS host resistance in wheat were outstanding! Proud mentors Karl Glover, @shysol4u.bsky.social. @sdstate.bsky.social. Moment with a fellow Plant Pathologist- Borlaug!

15.04.2025 21:57 — 👍 6    🔁 2    💬 2    📌 0

Last week we @plantpath.bsky.social, Mural lab, & Toporek lab celebrated graduate student appreciation week bringing togather plant protection and genomics groups at @sdstate.bsky.social A loud shoutout to Sachin, Israel, Riya, and Nikhil. Awesome combination of Food,Fun,Gifts & Graduates.

15.04.2025 03:11 — 👍 1    🔁 1    💬 0    📌 0

German and US flags

To US colleagues who have lost or are in imminent danger of losing their jobs: please DM whether we can accommodate your research.

15.02.2025 13:18 — 👍 309    🔁 135    💬 3    📌 2

White House pauses all federal grants, sparking confusion The Trump administration has put a hold on all federal financial grants and loans, affecting tens of billions of dollars in payments.

I think some people hear “grants” and think that without them, scientists and government workers just have less stuff to play with at work. But grants fund salaries for students, academics, researchers, and people who work in all areas of public service.

“Pausing” grants means people don’t eat.

28.01.2025 03:03 — 👍 43619    🔁 14460    💬 1592    📌 949

Fun time in lab: Keyence BZ-X800 demo by Conor. I guess everyone likes it!

26.01.2025 05:36 — 👍 3    🔁 1    💬 0    📌 0

Viewpoint: Crop biotechnology is China’s next leap forward in ‘smart agriculture’ Between 1990 and 2009, China's agricultural labor decreased by 5 percent while agricultural productivity increased by 6.5 percent a year. However,

‘All major national academies of sciences say that genetically modified crops are as safe as traditional crops.’ Still, regulations have curbed GMO adoption, limiting gains for farmers.

26.01.2025 00:05 — 👍 2    🔁 1    💬 1    📌 0