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NayimGR

@nayim.bsky.social

I like large rocks and small proteins. BIF fellow doing cryoEM+Protein Design in the Llorca lab β„οΈπŸ”¬

408 Followers  |  584 Following  |  6 Posts  |  Joined: 11.10.2023  |  2.0519

Latest posts by nayim.bsky.social on Bluesky

IOPP: Title Detail: Single particle Cryo EM of Biological Macromolecules by Robert M Glaeser This is an edited book that provides a comprehensive, accessible and authoritative introduction to the field of high-resolution structure analysis by single-particle cryo-EM. It covers all necessary b...

This one:

store.ioppublishing.org/page/detail/...

28.09.2025 00:50 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

I think the SPA textbook by Nogales, Glaeser and Wah Chiu might work

28.09.2025 00:50 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0
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I am excited to share our new preprint on the CAGE complex, a mysterious hollow protein complex that I first saw years ago while surveying Tetrahymena ciliary lysate www.biorxiv.org/content/10.1... #cilia #protistsonsky 🧬πŸ§ͺ

23.09.2025 17:08 β€” πŸ‘ 166    πŸ” 54    πŸ’¬ 7    πŸ“Œ 13
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The structure of the complete extracellular bacterial flagellum reveals the mechanism of flagellin incorporation - Nature Microbiology Cryo-electron microscopy analysis of the extracellular flagellum structure, including the hook–filament junction and filament cap complex, reveals mechanisms of flagellin incorporation into the growin...

The peer-reviewed version of our article on the flagellum filament assembly is out!
A masterpiece from duo extraordinaire Kailin and Rosa, and an incredibly productive collaboration with Marc Erhardt and Morgan Beeby.

01.07.2025 10:38 β€” πŸ‘ 38    πŸ” 13    πŸ’¬ 1    πŸ“Œ 1
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Cryo-EM structure of the vault from human brain reveals symmetry mismatch at its caps The vault protein is expressed in most eukaryotic cells, where it is assembled on polyribosomes into large hollow barrel-shaped complexes. Despite its widespread and abundant presence in cells, the bi...

The amazing Sofia LΓΆvestam initiated the below project, when she became interested in the vault particles that we sometimes observe in #cryoEM images of brain-derived #amyloid filaments.
www.biorxiv.org/content/10.1...

28.05.2025 07:33 β€” πŸ‘ 60    πŸ” 23    πŸ’¬ 2    πŸ“Œ 0
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🦠🧠 MemBrain update! 🧠🦠
We’ve updated our preprint! It now covers the full MemBrain v2 pipeline for end-to-end membrane analysis in #CryoET: segmentation, particle picking, and spatial statistics.
πŸ”— Preprint: doi.org/10.1101/2024...
πŸ”— Code: github.com/CellArchLab/...
🧡(1/6) #TeamTomo

25.04.2025 07:28 β€” πŸ‘ 78    πŸ” 34    πŸ’¬ 2    πŸ“Œ 5

If you process each of your dataset halves in different floors at Lumon you achieve *actual* gold-standard FSCs

27.03.2025 08:26 β€” πŸ‘ 2    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0
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Mature #HIV-1 contains >2000 copies of β€œspacer peptide 2”, but we didn’t know why. We now see that SP2 binds the matrix protein and triggers the change into its mature arrangement. Summary video from @margotriggi.bsky.social

28.02.2025 14:04 β€” πŸ‘ 131    πŸ” 51    πŸ’¬ 1    πŸ“Œ 9
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REGISTRATION OPEN!! - CNIO meeting, Machines acting on DNA and RNA, 2025 May 28-30th in Madrid, organized by @nogaleslab.bsky.social , @rfleiro.bsky.social , and @oscarllorca.bsky.social

10.01.2025 10:52 β€” πŸ‘ 5    πŸ” 3    πŸ’¬ 1    πŸ“Œ 0
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Interested in joining us? The Green Algorithms project promotes environmentally sustainable computational science through an online calculator, training material and other tools.

🚨We're recruiting! Interested in making science and computing more environmentally friendly? Now's the time!

Very excited to build a research group at Cambridge Uni to expand our Green Algorithms work thanks to the support of the Wellcome Trust
www.green-algorithms.org/join-us
#AcademicSky #SciSky

11.11.2024 17:15 β€” πŸ‘ 28    πŸ” 20    πŸ’¬ 3    πŸ“Œ 5

Missing the #FSCwars?

17.11.2024 14:49 β€” πŸ‘ 2    πŸ” 1    πŸ’¬ 1    πŸ“Œ 0

Here is a starter pack for CryoEM/ET enthousiasts
To be completed
go.bsky.app/JmQksC

08.11.2024 22:01 β€” πŸ‘ 110    πŸ” 76    πŸ’¬ 73    πŸ“Œ 6

Spilling the elutions of the first purification I got to work nicely while showing off that it was "so concentrated that is yellowish" to my labmates :')

16.11.2024 21:04 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

Wouldn't mind to be added, and @rfleiro.bsky.social surely wouldn't either :) thanks!

16.11.2024 20:27 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0

@nayim is following 20 prominent accounts