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@themorrislab.bsky.social

86 Followers  |  108 Following  |  4 Posts  |  Joined: 11.03.2025  |  1.6461

Latest posts by themorrislab.bsky.social on Bluesky

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Professor Jo Morris to Chair Medical Research Council's Molecular and Cellular Medicine Board - University of Birmingham The MRC has announced that Birminghamโ€™s Professor Jo Morris will become the new Chair of the MRC Molecular and Cellular Medicine Board (MCMB).

Looking forward to support the UKโ€™s fundamental biomedical research with the MRC www.birmingham.ac.uk/news/2025/pr...

30.04.2025 15:16 โ€” ๐Ÿ‘ 3    ๐Ÿ” 1    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 0
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Professor Jo Morris to Chair Medical Research Council's Molecular and Cellular Medicine Board - University of Birmingham The MRC has announced that Birminghamโ€™s Professor Jo Morris will become the new Chair of the MRC Molecular and Cellular Medicine Board (MCMB).

Looking forward to support the UKโ€™s fundamental biomedical research with the MRC www.birmingham.ac.uk/news/2025/pr...

30.04.2025 15:12 โ€” ๐Ÿ‘ 0    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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PIN1-SUMO2/3 motif suppresses excessive RNF168 chromatin accumulation and ubiquitin signaling to promote IR resistance Nature Communications - The ubiquitin ligase, RNF168, promotes DNA break repair but must be regulated to prevent run-away ubiquitin signaling. Here, the authors identify a three-step...

Nice to see this one out in @natcomms.nature.com from @themorrislab.bsky.social, @leneyms.bsky.social, @anoopsinghchauhan.bsky.social, @profstewartlab.bsky.social. Still, plenty of surprises into how RNF168 works!
rdcu.be/eiXxy

23.04.2025 12:12 โ€” ๐Ÿ‘ 1    ๐Ÿ” 1    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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PIN1-SUMO2/3 motif suppresses excessive RNF168 chromatin accumulation and ubiquitin signaling to promote IR resistance - Nature Communications The ubiquitin ligase, RNF168, promotes DNA break repair but must be regulated to prevent run-away ubiquitin signaling. Here, the authors identify a three-step post-translational cascade regulating RNF...

How is RNF168 cleared from sites of DNA damage? Itโ€™s complicated; www.nature.com/articles/s41...

15.04.2025 10:08 โ€” ๐Ÿ‘ 2    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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SUMO4 promotes SUMO deconjugation required for DNA double-strand-break repair Garvin etย al. find that the poorly explored SUMO isoform, SUMO4, enhances the deSUMOylation activity of the SUMO protease SENP1. Consequently, SUMO4 acts to restrain excessive cellular SUMOylation. In...

We are delighted to announce our first-ever BlueSky post โ€“ and the latest paper from our lab. with the Leney Lab @leneyms.bsky.social
dlvr.it/TJN3yl
@cp-molcell.bsky.social
@unibirmingham.bsky.social

11.03.2025 13:53 โ€” ๐Ÿ‘ 37    ๐Ÿ” 16    ๐Ÿ’ฌ 3    ๐Ÿ“Œ 0
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SUMO4 promotes SUMO deconjugation required for DNA double-strand-break repair Garvin etย al. find that the poorly explored SUMO isoform, SUMO4, enhances the deSUMOylation activity of the SUMO protease SENP1. Consequently, SUMO4 acts to restrain excessive cellular SUMOylation. In the DNA damage response, this activity preventsโ€ฆ

SUMO4 promotes SUMO deconjugation required for DNA double-strand-break repair

06.03.2025 23:57 โ€” ๐Ÿ‘ 4    ๐Ÿ” 2    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 1

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