MiccrobioTAckle

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Stay tuned for the drop!

🧬 Meet WP1 students!
Their focus? How the microbiome impacts cachexia across cancer types.
👨‍🔬Tongkun: cross-cancer multi-omics & ML models for diagnosis
👩‍🔬Mariem: epidemiology and microbiome of cachexia in colon cancer
👩‍🔬Mia: microbiome & muscle wasting links
👩‍🔬Rahma: cytokines & microbiome links

Here we are!
MiCCrobioTAckle is a @Horizoneu.bsky.social doctoral network coordinated by @Leibniz-HKI.de. Our goal is to advance research at the intersection between gut #microbiota and #cancer cachexia.
Follow us for exciting research!
#MSCA
#DoctoralNetworks
#HorizonEurope

Happy #WorldMicrobiomeDay!
Today, our last WP: From discovery to real treatments
🧬WP4 turns microbiota science into therapy for cancer cachexia.
Sagnik: designs FMT-based therapies, Anna: leads oral vs. tube-FMT trial, Colleen: builds consortium-in-a-pill

#FMTinAPill #GutMicrobiome #CancerCachexia

#MiCCrobioTAckle #CancerCachexia #GutMicrobiome #PhDResearch #Chronobiology #MicrobiotaMedicine #HorizonEurope #TranslationalScience

WP3 connects the dots:
WP1 finds microbial signatures
WP2 engineers therapeutic strains
WP3 tests cause–effect in vitro & in vivo
WP4 will bring delivery and translation innovations

Together, advancing microbiota-driven solutions against cancer cachexia!

🕒 Parul Sharma (University College Cork, Ireland)
Investigating how gut microbes link with circadian rhythms and whether
microbial therapies can reset biological clocks to ease cachexia.

🧪Louise Diependaele (DTU, Denmark):Belgian bioengineer developing in vitro models to study gut–host interactions and therapeutic microbes.
💪Devat Kandoriya (UCC, Ireland) Indian Pharmacologist exploring microbial and polyphenol therapies in mouse models, focusing on muscle strength and survival.

🔬 Validating Microbiome–Cachexia Links

In MiCCrobioTAckle, we’re uncovering how microbial imbalances drive cancer cachexia (CC).

Work Package 3 (WP3) dives into causality—testing how native or engineered microbes affect cachexia in experimental models.

Meet the WP3 PhD researchers:

💻 𝗕𝗼 𝗦𝘂𝗻 (HKI) – Using computational tools to optimize strain performance
We’re creating metabolically rewired strains & consortia to be tested in WP3 models
WP1 → WP2 → WP3… and WP4 coming soon
#MiCCrobioTAckle #MicrobiomeTherapeutics #CancerCachexia #GutMicrobiome
#SynBio #SystemsBiology #PhDLife

🧪 𝗘𝗻𝗴𝗶𝗻𝗲𝗲𝗿𝗶𝗻𝗴 𝗧𝗵𝗲𝗿𝗮𝗽𝗲𝘂𝘁𝗶𝗰 𝗠𝗶𝗰𝗿𝗼𝗯𝗲𝘀 | 𝗪𝗣𝟮
In our project tackling cancer cachexia, WP2 focuses on developing next-gen microbial therapeutics restoring gut barrier function and regulate appetite.
🎓𝗠𝗲𝗲𝘁 𝘁𝗵𝗲 𝘀𝘁𝘂𝗱𝗲𝗻𝘁𝘀:
🔬 𝗔𝗱𝗮𝗺 𝗝𝗲𝗻𝗼𝗳𝗮𝗹𝘃𝗶 (DTU) – Engineering 𝘚. 𝘣𝘰𝘶𝘭𝘢𝘳𝘥𝘪𝘪 to deliver gut-targeted therapies

Together, they uncover microbiome signatures to inform biomarker discovery & therapy development. Stay tuned! #CancerCachexia
#Microbiome #PhDResearch

🧬 Meet WP1 students!
Their focus? How the microbiome impacts cachexia across cancer types.
👨‍🔬Tongkun: cross-cancer multi-omics & ML models for diagnosis
👩‍🔬Mariem: epidemiology and microbiome of cachexia in colon cancer
👩‍🔬Mia: microbiome & muscle wasting links
👩‍🔬Rahma: cytokines & microbiome links

#MiCCrobioTAckle #CancerCachexia #GutMicrobiome #MicrobiomeResearch #PersonalizedMedicine #PhDResearch #ScienceForHealth

END

The gut microbiome regulates inflammation, metabolism, and appetite — all disrupted in cancer cachexia.
Our work aims to improve patient outcomes and create personalized medicine solutions.

Join us in celebrating #WorldMicrobiomeDay and supporting microbiome science!

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Our mission:
🔍 Understand how the gut microbiome drives cancer cachexia
🧬 Find biomarkers for early diagnosis and prognosis
💡 Develop new microbiome-based treatments

But why the gut microbiome?

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We’re a European research consortium training 12 PhD students across microbiology, computational biology, clinical research, and synthetic biology.
We are coordinated by @mbdlab.bsky.social at @leibniz-hki.de

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🌍 World Microbiome Day is almost here — June 27!

Microbiomes are communities of bacteria, fungi, and viruses that impact our health in huge ways. At MiCCrobioTAckle, we’re researching how the gut microbiome affects cancer cachexia — a serious condition affecting over 80% of cancer patients.

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Here we are!
MiCCrobioTAckle is a @Horizoneu.bsky.social doctoral network coordinated by @Leibniz-HKI.de. Our goal is to advance research at the intersection between gut #microbiota and #cancer cachexia.
Follow us for exciting research!
#MSCA
#DoctoralNetworks
#HorizonEurope