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Epigenome Technologies, pioneering in epigenetic and single-cell analysis, offers advanced assay kits and optimization services.
Learn how we used Droplet Paired-Tag to assess RNA expression and histone modifications in individual brain cells and PBMCs to identify novel cell-type-specific CREs and heritability factors linked to AD
#Epigenetics #SingleCell #DropletPairedTag #PairedTag #Multiomics #Alzheimers
bit.ly/4kgWMF3
Epigenetics Update – Investigation of a global mouse methylome atlas reveals subtype-specific copy number alterations in pediatric cancer models go.nature.com/4rWwxIG
Marc Zuckermann/Ulrich Schüller in Nat Genet
#Epigenetic #DNAm #Cancer
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Gain deeper insights at epigenometech.com
Epigenetics Update - CDCA7 facilitates MET1-mediated CG DNA methylation maintenance in centromeric heterochromatin via linker histone H1 bit.ly/4pAjdbg
#Epigenetics #DNAm #Chromatin
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High-resolution insights without cell sorting; epigenometech.com
Download our poster to learn how we used single-cell CUT&Tag and Droplet Paired-Tag to profile PBMCs, generating over 70,000 single-cell profiles and identifying vast numbers of cis-regulatory elements
#Epigenetics #SingleCell #DropletPairedTag #PairedTag #Multiomics
bit.ly/4kgWMF3
Epigenetics Update - Single-cell spatiotemporal transcriptomic and chromatin accessibility profiling in developing postnatal human and macaque prefrontal cortex go.nature.com/4acm9WM
#Epigenetic #Chromatin #Macaque #SingleCell #Multiomics
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Discover the breakthrough at epigenometech.com
Epigenetic Update - HERVH-derived eRNA activates a super-enhancer–driven ALDH1A3/SAT1 axis to promote ferroptosis escape and pancreatic cancer development bit.ly/3YnTIxG
#Epigenetics #Chromatin #Cancer
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Empower your research with high-res epigenetic insights at epigenometech.com
Epigenetics Update - Generative epigenetic landscapes map the topology and topography of cell fates bit.ly/4515eml
Paul François (Université de Montréal) reporting in PNAS
#Epigenetics #Chromatin #CellFate
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Perfect for cancer, immunology, and aging research; epigenometech.com
Epigenetics Update - Epigenetic regulation of cocaine intake through dopaminergic control of cholinergic interneurons in male mice go.nature.com/3KCEYrI
Emiliana Borrelli (University of California, Irvine)
#Epigenetics #Cocaine
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Gain deeper insights into gene regulation; epigenometech.com
Epigenome Technologies offers an end-to-end single-cell Paired-Tag service, the first multiomic assay that simultaneously captures RNA expression and epigenetic marks - we run the entire workflow - from preparation to data analysis
#Epigenetics #SingleCell #PairedTag #Multiomics
bit.ly/3HWFoaw
Epigenome Technologies offers an end-to-end Single-Cell CUT&Tag service
Our expert scientists run the entire workflow on your samples - from preparation to data analysis
#Epigenetics #SingleCell #CUTandTag
Find out more at: bit.ly/4kPxe2i
Epigenetics Update - Rate-limiting enzymes in nucleotide metabolism synchronize nucleotide biosynthesis and
chromatin formation bit.ly/4plJIRF
Shashank Srivastava and Daniel R. Foltz (Northwestern University) in Mol Cell
#Epigenetics #Chromatin
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Discover the breakthrough at epigenometech.com
Epigenetics Update - NAT10 promotes cancer metastasis by modulating p300/CBP activity through chromatin-
associated tRNA bit.ly/3KbkiXF
Ruhul Amin and Kent W. Hunter (NCI, NIH)
#Epigenetics #Cancer #Chromatin
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High-resolution insights without cell sorting; epigenometech.com
New from Epigenome Technologies: the first fully validated Single-Cell CUT&Tag kit
Fully compatible with 10x Chromium® (ATAC) or Fluent PiP-seq®
#Epigenetics #SingleCell #CUTandTag
Find out more at: bit.ly/4lquJDv
Epigenetics Update - Peritumoral colonic epithelial cell-derived GDF15 sustains colorectal cancer via regulation of
glycolysis and histone lactylation go.nature.com/4oDUGkj
#Epigenetics #Lactylation #Cancer #GDF15
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Empower your research with high-res epigenetic insights at epigenometech.com
Epigenetics Update - Mapping single-cell diploid chromatin fiber architectures using DAF-seq go.nature.com/48O7lfF
Andrew B. Stergachis (University of Washington) reporting in Nat Biotech
#Epigenetics #Chromatin
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Perfect for cancer, immunology, and aging research; epigenometech.com
Learn more about single-cell epigenetic profiling by downloading our guide to single-cell CUT&Tag and single-cell Paired-Tag that provides comparisons to other methods and bioinformatic insight
bit.ly/4r7CGRD
#Epigenetics #Multiomics #CUTandTag #10XGgenomics #ChIPSeq #SingleCell #PairedTag
Epigenetics Update - The fibroblast epigenome underlies SS18::SSX-mediated transformation in synovial sarcoma go.nature.com/3MfBjR1
T. Michael Underhill (University of British Columbia) in Nat Commun
#Epigenetics #Cancer #Sarcoma
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Gain deeper insights into gene regulation; epigenometech.com
Epigenetics Update - Lineage-determining transcription factors constrain cohesin to drive multi-enhancer oncogene regulation go.nature.com/3Me82WO
#Epigenetics #Cohesin #Chromatin
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Discover the breakthrough at epigenometech.com
Our expansion of single-cell epigenetics assays continues!
The Epigenome Technologies scCUT&Tag assay is now compatible with the BD Rhapsody platform
Learn more here: bit.ly/4lquJDv
#Epigenetics #BDrhapsody #CUTandTag #Chromatin #Multiomics #Singlecell #CUTandRUN #ChIPseq #ATACseq
Epigenetics Update - Heterochromatin epimutations impose mitochondrial dysfunction to confer antifungal resistance bit.ly/3XupYPn
Robin C. Allshire/Alison L. Pidoux (Uni. Edinburgh) in EMBO J
#Epigenetics #Chromatin #AntiFungal
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High-resolution insights without cell sorting; epigenometech.com
Epigenetics Update - Reciprocal control of metabolic and chromatin regulators improves rice tolerance to heat go.nature.com/4iAFDX6
Dao-Xiu Zhou (Huazhong Agricultural University) reported in Nat Commun
#Epigenetics #Chromatin #Rice
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Empower your research with epigenometech.com
We have recently expanded our single-cell epigenetics assays!
Our Emulsion scCUT&Tag assay is now compatible with the Illumina PIPseq platform
Learn more at lnkd.in/g3YqPrWY
#SingleCell #EpigenomeTech #PairedTag #Multiomics #Epigenetics #scCUTandTag #PIPseq
Epigenetics Update - VGLL1 contributes to both the transcriptome and epigenome of the developing trophoblast compartment bit.ly/3KpCpcc
Francesca Soncin reporting in PNAS
#Epigenetics #Trophoblast
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Perfect for cancer, immunology, and aging research; epigenometech.com
Epigenetics Update - Widespread association of Polycomb complex–deposited histone H2A monoubiquitylation with enhancers and neuronal gene regulation bit.ly/4rw5p2I
Arneet L. Saltzman in Sci Adv
#Epigenetics #Polycomb
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Gain deeper insights into gene regulation; epigenometech.com
Download our poster to learn how we applied Droplet Paired-Tag to Alzheimer's disease post-mortem brain tissue to reveal specific cellular changes and potential therapeutic targets
#Epigenetics #SingleCell #DropletPairedTag #PairedTag #Multiomics #Alzheimers
bit.ly/4kgWMF3
Epigenetics Update - Single-molecule views of chromatin accessibility and structure during photomorphogenesis bit.ly/48GlI5z
Xing Wang Deng and Linhua Sun reported in PNAS
#Epigenetics #Chromatin #Plants #Photomorphogenesis
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Discover the breakthrough at epigenometech.com
Epigenetics Update - Thermodynamic principles link in vitro transcription factor affinities to single-molecule chromatin states in cells bit.ly/4iyvcDp
Emil Marklund and William J. Greenleaf in Cell
#Epigenetics #Chromatin
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High-resolution insights without cell sorting; epigenometech.com
Learn how we used Droplet Paired-Tag to assess RNA expression and histone modifications in individual brain cells and PBMCs to identify novel cell-type-specific CREs and heritability factors linked to AD
#Epigenetics #SingleCell #DropletPairedTag #PairedTag #Multiomics #Alzheimers
bit.ly/4kgWMF3
Epigenetics Update - NSD2 targeting reverses plasticity and drug resistance in prostate cancer go.nature.com/4imgShn
Chao Lu and Michael M. Shen (Columbia University) in Nature
#Epigenetics #ProstateCancer #NSD2 #H3K36me2
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Empower your research with: epigenometech.com
Epigenetics Update - Iron homeostasis and cell clonality drive cancer-associated intestinal DNA methylation drift in aging go.nature.com/4ijta9Y
Francesco Neri reporting in Nat Aging
#Epigenetics #DNAm #Cancer #Aging
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Perfect for cancer, immunology, and aging research; epigenometech.com
