@epigenometech.bsky.social
Epigenome Technologies, pioneering in epigenetic and single-cell analysis, offers advanced assay kits and optimization services.
Epigenetics Update - Acute NIPBL depletion reveals in vivo dynamics of loop extrusion and its role in transcription activation go.nature.com/4qIOxnH
Tessa M. Popay and Jesse R. Dixon (Salk) in Nat Genet
#Epigenetics #ChromatinLoops
---
Gain deeper insights into gene regulation; epigenometech.com
Some good news at the start of a new week β Epigenome Technologies is now on Substack!
Find us a epigenometech.substack.com, subscribe, and enjoy reading our blogs and articles!!!
#Substack #EpigenomeTech #Epigenetics #PairedTag #Epigenetics #SingleCell #Multiomics
Epigenetics Update - BRD4-mediated ER membrane contact creates functionally distinct mitochondrial subtypes
bit.ly/4kxXPSa
Costas A. Lyssiotis and Yatrik M. Shah (University of Michigan) reporting in Mol Cell
#Epigenetics #BRD4 #Mitochondria
---
Discover the breakthrough at epigenometech.com
Epigenetics Update - Cognitive rejuvenation through partial reprogramming of engram cells bit.ly/4qDqMgZ
Johannes GrΓ€ff and Gabriel Berdugo-Vega (EPFL) reporting in Neuron
#Epigenetics #Aging #Reprogramming
---
High-resolution insights without cell sorting; epigenometech.com
Download our poster to learn how we used single-cell CUT&Tag and Droplet Paired-Tag to profile PBMCs, generating over 70,000 single-cell profiles and identifying vast numbers of cis-regulatory elements.
#Epigenetics #SingleCell #DropletPairedTag #PairedTag #Multiomics
bit.ly/4kgWMF3
Epigenetics Update - Matrix-bound nanovesicles as epigenetic modulators of myeloid cells bit.ly/3O8T5GE
Stephen F. Badylak (University of Pittsburgh) reporting in Sci Adv
#Epigenetics #Nanovesicles #ExtracellularVesicles #Chromatin
---
Empower your research at epigenometech.com
Epigenetics News - Growth of Spreading Pancreatic Cancer Fueled By "Under-Appreciated" Epigenetic Changes bit.ly/4bOQzPx
#Epigenetics #News #Cancer #PancreaticCancer
---
Perfect for cancer, immunology, and aging research; epigenometech.com
Epigenome Technologies offers an end-to-end Single-Cell Paired-Tag service, the first multiomic assay that simultaneously captures RNA expression and epigenetic marks from preparation to data analysis
#Epigenetics #SingleCell #PairedTag #Multiomics
bit.ly/3HWFoaw
Epigenetics Update - The human BAF chromatin remodeler processes nucleosomes bound by pioneer transcription factors OCT4βSOX2 bit.ly/4aJoxDY
Nicolas H. ThomΓ€ (EPFL) reporting in Mol Cell
#Epigenetics #BAF #OCT4 #SOX2
---
Gain deeper insights into gene regulation; epigenometech.com
Epigenetics News - Worrying About Aging May Actually Age Women Faster bit.ly/46LletB
Anxiety about growing older, declining health linked to aging-related biological changes
#Epigenetics #News #Aging
---
Discover the breakthrough at epigenometech.com
New Epigenome Technologies Blog post! bit.ly/4a8XOR5
"Exploration of a Novel Epigenetic Mechanism Contributing to Cancer Metastasis"
Based on a Mol Cell study by Ruhul Amin and Kent W. Hunter
#Epigenetics #Blogs #Cancer #Metastasis #Chromatin
Epigenetics Update - TTNPB Promotes Human Pluripotent Stem Cell-to-Neural Stem Cell Transition via Modulation of Chromatin Accessibility and the S-(5β²-adenosyl)-L-homocysteine/Choline Metabolic Network bit.ly/3M3sWZd
#Epigenetics #PluripotentStemCells #Metabolism #NSCs
---
epigenometech.com
Epigenetics Update - The conserved N-terminal SANT1-binding domain (SBD) of EZH2 regulates PRC2 activity bit.ly/460jVa1
Agata L. Patriotis (Rockefeller University) reporting in Genes Dev
#Epigenetics #EZH2 #PRC2
---
Perfect for cancer, immunology, and aging research; epigenometech.com
New from Epigenome Technologies: Paired-Tag - the first single-cell multiomic assay that simultaneously captures RNA expression and epigenetic marks
#Epigenetics #SingleCell #PairedTag #Multiomics
Find out more at: bit.ly/4efqM1Y
Epigenetics Update - A microenvironment-determined risk continuum refines subtyping in meningioma and reveals determinants of machine learning-based tumor classification go.nature.com/4aHhxra
#Epigenetics #Meningioma #Cancer
---
Gain deeper insights into gene regulation; epigenometech.com
Epigenetics Update - Unbalanced chromatin binding of Polycomb complexes drives neurodevelopmental disorders bit.ly/3ObNmzE
Lluis Morey (University of Miami) reporting in Mol Cell
#Epigenetics #Chromatin #Polycomb #Neurodevelopment
---
Gain deeper insights into gene regulation; epigenometech.com
Learn more about single-cell epigenetic profiling by downloading our guide to scCUT&Tag and scPaired-Tag, which provides comparisons to other methods and bioinformatic insight
Learn more here: bit.ly/4r7CGRD
#Epigenetics #Multiomics #CUTandTag #10XGgenomics #ChIPSeq #SingleCell #PairedTag
Epigenetics Update - Precise control of transcription condensates across S phase balances linker histone expression with DNA replication, ensuring genome stability bit.ly/3NWpeB3
Joshua C. Saldivar in Mol Cell
#Epigenetics #Histones
---
Discover the breakthrough at epigenometech.com
Epigenetics Update - Transient histone deacetylase inhibition induces cellular memory of gene expression and 3D genome folding go.nature.com/4ae5JeL
#Epigenetics #Chromatin #GenomeFolding
---
High-resolution insights without cell sorting; epigenometech.com
We offer an end-to-end single-cell Paired-Tag service, the first multiomic assay that simultaneously captures RNA expression and epigenetic marks - our scientists run the entire workflow on your samples - from prep to data analysis
#Epigenetics #SingleCell #PairedTag #Multiomics
bit.ly/3HWFoaw
Epigenetics Update - DOT1L provides transcriptional memory through PRC1.1 antagonism go.nature.com/4qh5aXB
Chen Davidovich and Omer Gilan (Monash University) reporting in Nat Cell Biol
#Epigenetics #DOT1L #PolyComb
---
Gain deeper insights into gene regulation; epigenometech.com
Epigenetics Update - ZFTAβRELA ependymomas make itaconate to epigenetically drive fusion expression go.nature.com/49Ydk2b
Sriram Venneti (University of Michigan) reporting in Nature
#Epigenetics #Ependymoma #Itaconate
---
Discover the breakthrough at epigenometech.com
New from Epigenome Technologies: Paired-Tag - the first single-cell multiomic assay that simultaneously captures RNA expression and epigenetic marks
#Epigenetics #SingleCell #PairedTag #Multiomics
Find out more at: bit.ly/4efqM1Y
Epigenetics Update - Regulatory grammar in human promoters uncovered by MPRA-based deep learning go.nature.com/4agam7Y
Jeroen de Ridder and Bas van Steensel reporting in Nature
#Epigenetics #Model #MPRA
---
High-resolution insights without cell sorting; epigenometech.com
Epigenetics Update - Atlas-guided discovery of transcription factors for T cell programming go.nature.com/46mVZxz
H. Kay Chung (UNC), Susan M. Kaech (Allen Institute), and Wei Wang (UCSD) reporting in Nature
#Epigenetics #Reprogramming #Atlas
---
Empower your research at: epigenometech.com
New Epigenome Technologies Blog post! bit.ly/4khsu6a
"Single-Cell Epigenetic Analyses Implicate Dynamic Oligodendroglial Cell Activity during Multiple Sclerosis Progression"
Based on a Nat Neurosci study from Gonçalo Castelo-Branco
#Epigenetics #Blogs #MultipleSclerosis #SingleCell
Paired-Tag in the Wild! β βAn Integrated Single-Cell and Epigenomic Resource for Comparative Analysis of the Basal Gangliaβ bit.ly/49VSUXA
A bioRxiv article from Daofeng Li analyzes data from Paired-Tag from #EpigenomeTech
#Epigenetics #PairedTag #Multiomics #SingleCell #Chromatin
Paired-Tag in the Wild! β βSingle-Cell Atlas of Transcription and Chromatin States Reveals Regulatory Programs in the Human Brainβ bit.ly/4kbZdK2
A new bioRxiv article from Bing Ren/Lei Chang employs Droplet Paired-Tag from #EpigenomeTech
#Epigenetics #PairedTag #Multiomics #SingleCell #Chromatin
Epigenome Technologies offers an end-to-end Single-Cell CUT&Tag service
Our expert scientists run the entire workflow on your samples - from preparation to data analysis
#Epigenetics #SingleCell #CUTandTag
Find out more at: bit.ly/4kPxe2i
Epigenetics Update - EZH2 directs HER2+ breast cancer progression through the modulation of epithelial plasticity bit.ly/4qOfmYw
William J Muller (McGill University) reporting in EMBO Rep
#Epigenetics #EZH2 #BreastCancer
---
Perfect for cancer, immunology, and aging research; epigenometech.com
