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Rob O'Brien

@ascientistinvt.bsky.social

A scientist in VT. I'm into the outdoors, gardening, board games, D&D and books.

53 Followers  |  76 Following  |  6 Posts  |  Joined: 01.12.2024  |  1.5056

Latest posts by ascientistinvt.bsky.social on Bluesky

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Rock of Ages quarry ends tours and closes visitors center - VTDigger The Barre-based granite company has been a draw for locals and tourists for more than a century.

The Barre-based granite company has been a draw for locals and tourists for more than a century.

18.02.2025 22:34 β€” πŸ‘ 5    πŸ” 2    πŸ’¬ 0    πŸ“Œ 0

cool, we always wondered about the timing of microglia repopulation when you nuke them with the plexxikon molecule. Much more elegant to kill the xl-addicted cells. The question is always "do xl-addicted cells = senescent cells?" It's a harder question to answer than it seems, at least in vivo.

27.01.2025 20:37 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0

Cool stuff! I haven't read the paper yet, but I will.

Back in my Unity days we were very interested in senescent microglia, but decided to focus on the retina instead. Do you think you would get similar results with a molecule like Plexxikon's CSFR1 inhibitor, which generally wipes out microglia?

27.01.2025 18:59 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0
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Lake Champlain really has been exceptional this week

25.01.2025 21:01 β€” πŸ‘ 2    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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new ice with Whiteface in the background

22.01.2025 17:32 β€” πŸ‘ 2    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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I went skiing the other day and accidentally went up (the closed and unplowed) Honey Hollow road rather than the Honey Hollow trail. I was rewarded with a glimpse into someone's little slice of paradise in the hills of VT

22.01.2025 01:15 β€” πŸ‘ 2    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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Ok, guess it is time to make a post. This week has been great for skating here in Vermont. I'm lucky to have a family who loves to be outside as much as I do.

22.01.2025 01:08 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

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