Extrusion fountains are restricted by WAPL-dependent cohesin release and CTCF barriers
Abstract. Interphase chromosomes are mainly shaped by loop extrusion and compartmentalisation mechanisms. However, their temporal component and cause-effec
(1/n) Excited to present the latest work from the de Wit lab, where we identify and characterise loop extrusion-mediated fountains in mammalian genomes using acute depletion of 3D genome regulators: doi.org/10.1093/nar/.... A Bluetorialπ§΅:
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π’TOMORROW, APRIL 8THπ’ Join your coworkers at your local Kill the Cuts rally and fight to save lifesaving research, healthcare, and education!
07.04.2025 22:33 β π 16 π 6 π¬ 0 π 1
The @keystonesymposia.bsky.social Chromatin Architecture/Transcription Regulation meeting has been fascinating so far! Catch my talk Tuesday (last slot before dinner) and my poster #2501 to learn about how cohesin regulates enhancers.
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Hundreds rally in S.F. in support of science as Trump threatens jobs, funding
Hundreds of people rallied outside San Francisco's City Hall in support of science as Trump slashes jobs and funding
Hundreds of people gathered at a Stand Up for Science rally outside San Francisco City Hall on Friday, protesting in the face of widespread cuts and layoffs from the Trump administration.
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Feeling energized to call your elected officials? Here's a script and phone numbers (geared for California/UCSF but easily adaptable): shorturl.at/3ePi0
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Independent journalism with a BITE.
www.coyotemedia.org
Drosophila geneticist, mol-cell biol., professor, raconteur.
I love mutants.
Group leader at Institut Jacques Monod. When I say "epigenetics" what I really mean is "DNA methylation".
www.maximgreenberglab.com
Postdoctoral researcher in Nadav Ahituvβs lab at UCSF. Interested in genome instability, neurodegeneration, chromatin and transcription regulation.
CA State Senator, representing San Francisco & northern San Mateo County. Chair, Senate Budget Committee. Passionate about health care, climate, making it easier/faster to build good things like housing, transit, clean energy. Democrat π³οΈβπβ‘οΈποΈscottwiener.com
Lab head in stem cell and cancer epigenetics at PeterMac, UniMelb π¦πΊπ§¬
Scientist, mum, dreamer
She/her. Views are my own
www.eckmaslab.com
Clinic-minded genome + epigenome editor. Professor of Molecular Therapeutics, UC Berkeley. Director for Technology and Translation, Innovative Genomics Institute, ibid.
Beatles fan.
Art work credit: Fyodor Vasiliev "A Meadow in the Rain" (1872).
Asst Prof, U Maryland. Islamicate Affect/Emotion, Sufism, Digital Humanities, Persian literature, Lit of Islamic & Middle Eastern Revolutionary Movements, Labor. On Piscataway Land. Proud Member: AAUP (@aaup.bsky.social), AFT (@aftunion.bsky.social)
PhD student in Andrea Brand's lab at NYU Langone and University of Cambridge, studying epigenomics in neural stem cells π§¬π¬π§
LMCB Group Leader at UCL. Cis-regulatory control of cell fate choice in development.
https://delaslab.com/
Interested in chromatin dynamics during mammalian development
Founder of Liminal (LiminalCreations.com) & co-founder of Unbreaking (Unbreaking.org) Focused on turning knowledge into action. #science #communication #sensemaking #scicomm She/her. Married to Ed Yong.
shendure lab |. krishna.gs.washington.edu
Studying how transcription factor dosage is utilized in development and perturbed in disease. Faculty at Boston Childrenβs Hospital/Harvard Medical School. naqvilab.org
Uses functional genomics to study astrocytes in neurodegenerative disease π§ͺ. Neuroscience PhD candidate at UCSF (Kampmann Lab). He/him π³οΈβπ
Study genetic conflicts professionally. Try to avoid conflicts in personal life (with mixed results).
Fred Hutch Basic Sciences
(https://go.bsky.app/ReCeiC6)
UW Genome Sciences (go.bsky.app/L8RAbiJ)
HHMI (hhmi.bsky.social)
Posting in a personal capacity.
Epigenetic Inheritance, Neuroscience & anything biology-related
https://www.odedrechavilab.com/
TED: https://shorturl.at/myFTY
Huberman Lab Podcast: https://youtu.be/CDUetQMKM6g
Assistant Professor at @UCSF_BTS | @HHMINEWS HGF | | Loving membrane proteins every day https://www.wcoyotelab.com