Vladimir Volkov 🇺🇦

and if we imagine that the increase in the number of projects submitted may also be due to the use of AI, we will end up with an AI evaluating an AI 🫣

🫣

#LLPS #Droplets #phaseseparation

Congratulations to the new cohort of 28 EMBO Young Investigators! They are joining an international network of more than 800 life scientists – Welcome!

Read the press release here:
https://www.embo.org/press-releases/twenty-eight-group-leaders-become-embo-young-investigators/

From what I can read, the X scale is in Russian, which is certainly not the language the rest of the paper is written in..

Your periodic reminder that science is not done by a few selected "stars scientists". Science is done by hundred of thousands. Siloed money mean a few flashy discoveries and a lot of waste. Want to change things? Make funding accessible and stop funding calls with less than 2% success rate.

ERC success rates are tanking and the move is... even bigger grants for fewer people? smh

New preprint! We measured temperature- and pH-induced aggregation for over 18,000 natural and de novo designed protein domains!

A paper design for cutting out some sort of snowflake

On the first day of Christmas, a virus gave to me...

Write a letter of support to help keep Jalview funded! Jalview’s core funding from the Wellcome Trust ends in 2026, and we are now preparing an application to the UK’s BBSRC to support Jalview into the next decade. You can help us keep Jalview available ...

I just found this now. @jalview.bsky.social team needs your support for their BBSRC application. Deadline tomorrow!

discourse.jalview.org/t/write-a-le...

In situ structural mechanism of epothilone-B-induced CNS axon regeneration - Nature A combined cryo-electron tomography and cryo-electron microscopy pipeline was developed to inflict axonal damage and monitor the cellular response induced by epothilone B, revealing that mic...

In situ structural mechanism of epothilone-B-induced CNS axon regeneration www.nature.com/articles/s41...

Interested in pursuing a PhD by working on a long-neglected marine organism and making a lot of discoveries? Darwin Trust offers a PhD studentship for international students (anyone non-UK) www.findaphd.com/phds/project...

Screenshot of page 1 of Franklin and Gosling

Screenshot of page 2 of Franklin and Gosling

I am seeing a lot of posts about Rosalind Franklin that themselves ignore her publication record on DNA!

In fact Franklin and Gosling's paper, including the famous Photograph #51, was published, along with Wilkins's paper, back-to-back with the Watson and Crick paper in Nature in 1953.

Please repost - Multiple PhDs available

www.findaphd.com/phds/project...

www.findaphd.com/phds/project...

www.findaphd.com/phds/project...

‘Epigenetic serum’ makes you wonder !

Icecream: High-Fidelity Equivariant Cryo-Electron Tomography Cryo-electron tomography (cryo-ET) visualizes 3D cellular architecture in near-native states. Recent deep-learning methods (CryoCARE, IsoNet, DeepDeWedge, CryoLithe) improve denoising and artifact cor...

Our colleagues Vinith Kishore and Valentin Debarnot from the @ivandokmanic.bsky.social lab have come up with an amazing deep learning tool for denoising and filling the missing wedge in #cryoET data. I'm pleased to introduce Icecream🍧

Two back-to-back stories on mitosis led by my incredible postdoc @krunovuk.bsky.social at @institutrb.bsky.social, in which we challenge the gliding model of CENP-E-driven chromosome congression! Today in @natcomms.nature.com
doi.org/10.1038/s414...
doi.org/10.1038/s414...

Aging as a PI: I read less papers and have less people to talk to. I'm starting to think I'll get into LLMs at some point 🥲

Dick is one of the most thoughtful folks in cell biology--this is a must read for anyone interested in microtubules!

Perspective from Richard McIntosh describing the history of research on #microtubule polymerization in terms of the ideas, technologies, and observations that have emerged as countless researchers have studied the dynamics of these essential cytoskeletal polymers. rupress.org/jcb/article/...

Screenshot of LinkedIn’s menu: “How LinkedIn uses your data”. Near the bottom, is the option to turn off “Data for Generative AI improvement”, shown with a red arrow.

🤖 If you use LinkedIn, please be aware that they automatically use your profile to train their GenAI. To turn off, go to Settings > Data Privacy > Data for Gen AI improvements.

So when I hear of students being encouraged to use GPT in college I don’t hear innovation. I hear cognitive atrophy, the inability to think critically for oneself, and total dependence on vulnerable centralized repositories of data for knowledge without ever understanding how knowledge is generated.

Thousands more university jobs cut as financial crisis deepens University workers will vote on national strike action this month over a 1.4% pay offer made in the summer.

UK Universities cut 12,000 jobs, more on the way.

40% of Unis in financial crisis.

Major exporter destroyed by successive govts

Obstacles for foreign students.
Low fees in England, lack of govt funding.
£267bn student debt.
Home student numbers down.

How will the UK compete with other nations?

Thrilled to share that the lab has been awarded a @wellcometrust.bsky.social Discovery Award to keep exploring the evolution of 6-methyladenine #6mA in Eukaryotes. We'll open postdoc (3️⃣) and tech (1️⃣) positions to start in 2026, please share with candidates or reach out if you’d like to join us.

The year 1984 is unfairly maligned. Have we considered changing the title of George Orwell’s classic to 2025?

Screenshot of text from the article.

Interesting article on public misconceptions about HE, including the value to the economy.

And yet our govt seem happy to sit back and let it all go to shit. 🤷🏻‍♂️ www.theguardian.com/education/20...

Immigrants, particularly on H1Bs, are the lifeblood of American innovation. If you wanted to hurt US competitiveness in the next century, I can think of few more effective ways than a move like this

Even when found illegal, the mere intent will have irreparably harmed our future

Can ChatGPT help science writers?

Tl;dr = No.

www.science.org/content/blog...

Genetically encoded FerriTag as a specific label for cryo-electron tomography Wang et al. present an optimized labeling strategy for cryo-electron tomography based on genetically encoded FerriTag. This system uses rapamycin to recruit iron-loaded ferritin to target proteins, en...

Paper alert🚨
Label your protein of interest and localize it in cryoET 👁️❄️

Genetically encoded FerriTag as a specific label for cryo-electron tomography: Structure www.cell.com/structure/fu...

These passages about what the UK gov is preparing for the HE sector are quite terrifying:

This reminds me how much I hate it when I have to watch a video tutorial. The reason books and libraries have been successful is that you can parse the information they contain many times faster than with a linear media or someone talking