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Jan Beumer, PharmD PhD DABT

@beumercancer.bsky.social

Pharmacology and drug development at Johns Hopkins University

49 Followers  |  265 Following  |  5 Posts  |  Joined: 10.02.2025  |  1.4506

Latest posts by beumercancer.bsky.social on Bluesky

Happy to have this work come to light based on Joshua Deppas and Brian Kiesel graduate work at @upmchillmancc.bsky.social

authors.elsevier.com/a/1l3Ro,xhCD...

08.05.2025 17:23 โ€” ๐Ÿ‘ 0    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

As usual, nuance and understanding the context is importantโ€ฆ Iโ€™ve seen some good examples of the importance of studying both sexesโ€ฆ but the policy has been interpreted rather strictly

25.02.2025 15:51 โ€” ๐Ÿ‘ 3    ๐Ÿ” 0    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 0

Often it is due to sex differences in drug metabolism in rodents, which do not replicate in humans. So the blanket duplication of experiments may needlessly increase animal use, or worse (if mixing male and female animals) will increase within-group variability and diminish statistical power.

25.02.2025 15:49 โ€” ๐Ÿ‘ 3    ๐Ÿ” 0    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 0

And then return the change due

12.02.2025 21:01 โ€” ๐Ÿ‘ 1    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

Wasnโ€™t the snow asbestos?

12.02.2025 20:58 โ€” ๐Ÿ‘ 0    ๐Ÿ” 0    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 0

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